Publications by authors named "Sing-Ru Lin"

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Dissociation of the nuclear WWOX/TRAF2 switch renders UV/cold shock-mediated nuclear bubbling cell death at low temperatures.
Szu-Jung Chen, Cheng-Chang Tsai, Sing-Ru Lin, Ming-Hui Lee, Shenq-Shyang Huang

Cell Commun Signal· October 2024

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Therapeutic Zfra4-10 or WWOX7-21 Peptide Induces Complex Formation of WWOX with Selective Protein Targets in Organs that Leads to Cancer Suppression and Spleen Cytotoxic Memory Z Cell Activation In Vivo.
Wan-Pei Su, Wan-Jen Wang, Jean-Yun Chang, Pei-Chuan Ho, Tsung-Yun Liu, Hsiang-Ling Kuo, Sing-Ru Lin

Cancers (Basel)· August 2020

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WWOX Possesses -Terminal Cell Surface-Exposed Epitopes WWOX and WWOX for Signaling Cancer Growth Suppression and Prevention In Vivo.
Wan-Jen Wang, Pei-Chuan Ho, Ganesan Nagarajan, Yu-An Chen, Hsiang-Ling Kuo, Sing-Ru Lin

Cancers (Basel)· November 2019

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A p53/TIAF1/WWOX triad exerts cancer suppression but may cause brain protein aggregation due to p53/WWOX functional antagonism.
Pei-Yi Chou, Sing-Ru Lin, Ming-Hui Lee, Lori Schultz, Chun-I Sze

Cell Commun Signal· July 2019

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Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation.
Ming-Hui Lee, Yao-Hsiang Shih, Sing-Ru Lin, Jean-Yun Chang, Yu-Hao Lin

Alzheimers Dement (N Y)· June 2017

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Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed.
Li-Jin Hsu, Qunying Hong, Shur-Tzu Chen, Hsiang-Lin Kuo, Lori Schultz, Sing-Ru Lin, Zih-Ling Li

Oncotarget· March 2017

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Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain.
Jean-Yun Chang, Ming-Hui Lee, Sing-Ru Lin, Li-Yi Yang, H Sunny Sun, Yee-Shin Lin

Oncotarget· February 2015

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Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.
Ming-Hui Lee, Wan-Pei Su, Wan-Jen Wang, Sing-Ru Lin, Chen-Yu Lu

Oncotarget· February 2015

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Identification of an In Vivo MEK/WOX1 Complex as a Master Switch for Apoptosis in T Cell Leukemia.
Hsin-Ping Lin, Jean-Yun Chang, Sing-Ru Lin, Ming-Hui Lee, Shenq-Shyang Huang

Genes Cancer· May 2011

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Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats.
Meng-Yen Li, Feng-Jie Lai, Li-Jin Hsu, Chen-Peng Lo, Ching-Li Cheng, Sing-Ru Lin

PLoS One· November 2009

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Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1.
Li-Jin Hsu, Lori Schultz, Qunying Hong, Kris Van Moer, John Heath, Sing-Ru Lin, Yee-Shin Lin

J Biol Chem· June 2009

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Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells.
Qunying Hong, Chun-I Sze, Sing-Ru Lin, Ming-Hui Lee, Ruei-Yu He

PLoS One· June 2009

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Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.
Li-Jin Hsu, Qunying Hong, Lori Schultz, Emory Kuo, Sing-Ru Lin, Yee-Shin Lin

Cell Signal· July 2008

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MPP+-induced neuronal death in rats involves tyrosine 33 phosphorylation of WW domain-containing oxidoreductase WOX1.
Chen-Peng Lo, Li-Jin Hsu, Meng-Yen Li, Se-Yei Hsu, Jih-Ing Chuang, Sing-Ru Lin

Eur J Neurosci· April 2008

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