Publications by authors named "Siquan Sun"

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Retraction: The PAR2 signal peptide prevents premature receptor cleavage and activation.
Belinda Liu, Grace Lee, Jiejun Wu, Janise Deming, Chester Kuei, Siquan Sun

PLoS One· June 2024

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Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
Aaron A Thompson, Michael B Harbut, Pei-Pei Kung, Nathan K Karpowich, Jeffrey D Branson, Siquan Sun

Proc Natl Acad Sci U S A· May 2023

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Identification and characterization of select oxysterols as ligands for GPR17.
Anthony W Harrington, Changlu Liu, Naomi Phillips, Diane Nepomuceno, Chester Kuei, Siquan Sun

Br J Pharmacol· February 2023

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Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse.
William A Eckert, John J M Wiener, Hui Cai, Michael K Ameriks, Jian Zhu, Siquan Sun

Eur J Pharmacol· August 2020

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The PAR2 signal peptide prevents premature receptor cleavage and activation.
Belinda Liu, Grace Lee, Jiejun Wu, Janise Deming, Chester Kuei, Siquan Sun

PLoS One· April 2020

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LC/MS/MS Profiling of Tissue Oxysterols and its Application in Dextran Sodium Sulphate Induced Mouse Colitis Models.
Jiejun Wu, J Eric McDuffie, Jiao Song, Michael C Harris, Holly Raymond, Siquan Sun

Curr Top Med Chem· September 2017

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Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability.
Xiaohu Deng, Siquan Sun, Jiejun Wu, Chester Kuei, Victory Joseph

Bioorg Med Chem Lett· October 2016

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7α, 25-dihydroxycholesterol-mediated activation of EBI2 in immune regulation and diseases.
Siquan Sun, Changlu Liu

Front Pharmacol· April 2015

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Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.
Pejman Soroosh, Jiejun Wu, Xiaohua Xue, Jiao Song, Steven W Sutton, Siquan Sun

Proc Natl Acad Sci U S A· August 2014

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Pyrazole-based arylalkyne cathepsin S inhibitors. Part III: modification of P4 region.
John J M Wiener, Alvah Tyson Wickboldt, Steven Nguyen, Siquan Sun, Raymond Rynberg

Bioorg Med Chem Lett· February 2013

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Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site.
Li Zhang, Amy Y Shih, Xia V Yang, Chester Kuei, Jiejun Wu, Siquan Sun

Mol Pharmacol· December 2012

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Oxysterols direct B-cell migration through EBI2.
Changlu Liu, Xia V Yang, Jiejun Wu, Chester Kuei, Neelakandha S Mani, Siquan Sun

Nature· July 2011

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Cathepsin S inhibitors: 2004-2010.
Alice Lee-Dutra, Danielle K Wiener, Siquan Sun

Expert Opin Ther Pat· March 2011

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Recent advances in the design of cathepsin S inhibitors.
John J M Wiener, Siquan Sun, Robin L Thurmond

Curr Top Med Chem· July 2010

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Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors.
Michael K Ameriks, Scott D Bembenek, Matthew T Burdett, Ingrid C Choong, James P Edwards, Siquan Sun

Bioorg Med Chem Lett· July 2010

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Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors: part 1.
Alice Lee-Dutra, Danielle K Wiener, Kristen L Arienti, Jing Liu, Neelakandha Mani, Siquan Sun

Bioorg Med Chem Lett· April 2010

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Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors. Part 2: Modification of P3, P4, and P5 regions.
John J M Wiener, Alvah T Wickboldt, Danielle K Wiener, Alice Lee-Dutra, James P Edwards, Siquan Sun

Bioorg Med Chem Lett· April 2010

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Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors.
Danielle K Wiener, Alice Lee-Dutra, Scott Bembenek, Steven Nguyen, Robin L Thurmond, Siquan Sun

Bioorg Med Chem Lett· April 2010

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Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements.
Michael K Ameriks, Frank U Axe, Scott D Bembenek, James P Edwards, Yin Gu, Siquan Sun

Bioorg Med Chem Lett· November 2009

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Pyrazole-based arylalkyne cathepsin S inhibitors. Part II: optimization of cellular potency.
Michael K Ameriks, Hui Cai, James P Edwards, Damara Gebauer, Elizabeth Gleason, Siquan Sun

Bioorg Med Chem Lett· November 2009

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TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disorders.
Siquan Sun, Navin L Rao, Jennifer Venable, Robin Thurmond, Lars Karlsson

Inflamm Allergy Drug Targets· December 2007

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Pyrazole-based cathepsin S inhibitors with improved cellular potency.
Jianmei Wei, Barbara A Pio, Hui Cai, Steven P Meduna, Siquan Sun

Bioorg Med Chem Lett· October 2007

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The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors.
Cheryl A Grice, Kevin Tays, Haripada Khatuya, Darin J Gustin, Christopher R Butler, Siquan Sun

Bioorg Med Chem Lett· April 2006

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CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion.
Miguel A Sanjuan, Navin Rao, Kuei-Tai A Lai, Yin Gu, Siquan Sun

J Cell Biol· March 2006

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Cathepsin S inhibitors as novel immunomodulators.
Robin L Thurmond, Siquan Sun, Lars Karlsson, James P Edwards

Curr Opin Investig Drugs· May 2005

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