Publications by authors named "Siteng Fang"

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Dissecting the Efficacy and Immunogenicity of TLR7 Agonist-Antibody Conjugates through the Lens of Fc Effector Function, Conjugation Strategies, and Linker Cleavability.
Siteng Fang, Samantha R Benjamin, Lina Wu, Mohammad Asikur Rahman, Kayla K Elder

J Med Chem· December 2025

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ValCitGlyPro-dexamethasone antibody conjugates selectively suppress the activation of human monocytes.
Justin M Howe, Siteng Fang, Kelsey A Watts, Fanny Xu, Samantha R Benjamin

RSC Med Chem· November 2023

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Synthesis and Optimization of 1-Substituted Imidazo[4,5-]quinoline TLR7 Agonists.
Emma G DeYoung, Justin M Howe, Siteng Fang, Mullapudi Mohan Reddy, Jillian P Handel

ACS Med Chem Lett· October 2023

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Evaluation of an ester-linked immunosuppressive payload: A case study in understanding the stability and cleavability of ester-containing ADC linkers.
Courtney P Jackson, Siteng Fang, Samantha R Benjamin, Tchilabalo Alayi, Yetrib Hathout

Bioorg Med Chem Lett· November 2022

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Design and Characterization of Immune-Stimulating Imidazo[4,5-c]quinoline Antibody-Drug Conjugates.
Siteng Fang, Brittany M Brems, Emmanuel O Olawode, Jared T Miller, Tracy A Brooks

Mol Pharm· September 2022

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Enzyme-Agnostic Lysosomal Screen Identifies New Legumain-Cleavable ADC Linkers.
Jared T Miller, Caitlin N Vitro, Siteng Fang, Samantha R Benjamin, L Nathan Tumey

Bioconjug Chem· April 2021

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Thiolation of Q295: Site-Specific Conjugation of Hydrophobic Payloads without the Need for Genetic Engineering.
Samantha R Benjamin, Courtney P Jackson, Siteng Fang, Dane P Carlson, Zhongyuan Guo

Mol Pharm· June 2019

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