Publications by authors named "Slava Epelman"

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Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk.
Xiangyu Zhang, Divya Kapoor, Se-Jin Jeong, Alan Fappi, Jeremiah Stitham, Vasavi Shabrish, Ismail Sergin, Eman Yousif, Astrid Rodriguez-Velez, Yu-Sheng Yeh

February 2024

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Loss of ADAM17 in smooth muscle cells enhances their transformation to macrophage-like cells leading to more severe atherosclerosis in mice.
Ilamaran Meganathan, Tolga Kilic, Razoan Al Rimon, Tushar Naiya, Vidhya Krishnan, Slava Epelman

Atherosclerosis· December 2025

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Glyoxal is a superior fixative to formaldehyde in promoting antigenicity and structural integrity in murine cardiac tissues.
Allen C T Teng, Dev Mehangrey, Ava Vandenbelt, Karl Vearncombe, Justin D Callahan, Slava Epelman

J Mol Cell Cardiol Plus· June 2025

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Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis.
Alex Lac, Slava Epelman

Nat Rev Immunol· May 2025

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Endothelial dysfunction drives atherosclerotic plaque macrophage-dependent abdominal aortic aneurysm formation.
Danya Thayaparan, Takuo Emoto, Aniqa B Khan, Rickvinder Besla, Homaira Hamidzada, Slava Epelman

Nat Immunol· May 2025

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New Minimally Invasive Myocardial Ischemia/Reperfusion Approach.
Danielle Altieri, Kristina Lorenz, Slava Epelman

Circ Res· May 2025

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A heart-brain-spleen axis controls cardiac remodeling to hypertensive stress.
Sara Perrotta, Lorenzo Carnevale, Marialuisa Perrotta, Fabio Pallante, Tomasz P Mikołajczyk, Slava Epelman

Immunity· March 2025

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Heart-on-a-Chip Model of Epicardial-Myocardial Interaction in Ischemia Reperfusion Injury.
Dawn Bannerman, Simon Pascual-Gil, Qinghua Wu, Ian Fernandes, Yimu Zhao, Slava Epelman

Adv Healthc Mater· August 2024

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Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms.
Shira Landau, Yimu Zhao, Homaira Hamidzada, Gregory M Kent, Sargol Okhovatian, Slava Epelman

Cell Stem Cell· August 2024

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Myocardial Extracellular Volume Fraction Varies With Hemodynamic Load and After Pulmonary Valve Replacement in TOF.
Ayako Ishikita, Gauri R Karur, Kate Hanneman, Darren A Yuen, Rajiv R Chaturvedi, Slava Epelman

JACC Cardiovasc Imaging· July 2024

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Dissecting and Visualizing the Functional Diversity of Cardiac Macrophages.
Megan Holt, Julia Lin, Markus Cicka, Anthony Wong, Slava Epelman

Circ Res· June 2024

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Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways.
Homaira Hamidzada, Simon Pascual-Gil, Qinghua Wu, Gregory M Kent, Stéphane Massé, Slava Epelman

Nat Cardiovasc Res· May 2024

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CaSSiDI: novel single-cell "Cluster Similarity Scoring and Distinction Index" reveals critical functions for PirB and context-dependent Cebpb repression.
Robert Nechanitzky, Parameswaran Ramachandran, Duygu Nechanitzky, Wanda Y Li, Andrew C Wakeham, Slava Epelman

Cell Death Differ· March 2024

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Chimeric antigen receptor macrophages target and resorb amyloid plaques.
Alexander B Kim, Qingli Xiao, Ping Yan, Qiuyun Pan, Gaurav Pandey, Slava Epelman

JCI Insight· February 2024

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Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells.
Ian Fernandes, Shunsuke Funakoshi, Homaira Hamidzada, Slava Epelman, Gordon Keller

Nat Commun· December 2023

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Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling.
Pailin Chiaranunt, Kyle Burrows, Louis Ngai, Siu Ling Tai, Eric Y Cao, Slava Epelman

Sci Immunol· August 2023

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Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling.
Xiangyu Zhang, Trent D Evans, Sunny Chen, Ismail Sergin, Jeremiah Stitham, Slava Epelman

Circ Res· July 2023

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Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer's Disease.
Qiuyun Pan, Ping Yan, Alexander B Kim, Qingli Xiao, Gaurav Pandey, Slava Epelman

bioRxiv· May 2023

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Myocardial Inflammation on FDG PET/MRI and Clinical Outcomes in Symptomatic and Asymptomatic Participants after COVID-19 Vaccination.
Constantin Arndt Marschner, Paaladinesh Thavendiranathan, Dakota Gustafson, Kathryn L Howe, Jason E Fish, Slava Epelman

Radiol Cardiothorac Imaging· April 2023

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Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.

JAMA· April 2023

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Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis.
Xiangyu Zhang, Santosh Kumar Misra, Parikshit Moitra, Xiuli Zhang, Se-Jin Jeong, Slava Epelman

Autophagy· March 2023

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Unchecked autoreactive CD8 T cells wreak havoc in cancer immunotherapy.
Anthony Wong, Slava Epelman

Nat Cardiovasc Res· December 2022

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The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis.
Christiane Pleuger, Dingding Ai, Minea L Hoppe, Laura T Winter, Daniel Bohnert, Slava Epelman

Elife· December 2022

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Resident cardiac macrophages: Heterogeneity and function in health and disease.
Rysa Zaman, Slava Epelman

Immunity· September 2022

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Diversity in the Expressed Genomic Host Response to Myocardial Infarction.
Augustin Toma, Claudia Dos Santos, Beata Burzyńska, Monika Góra, Marek Kiliszek, Slava Epelman

Circ Res· June 2022

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