Publications by authors named "Sofia Guzzetti"

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Hierarchical cluster analysis and nonlinear mixed-effects modelling for candidate biomarker detection in preclinical models of cancer.
David Hodson, Hitesh Mistry, James Yates, Sofia Guzzetti, Michael Davies

Eur J Pharm Sci· June 2024

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Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.
Anna D Staniszewska, Domenic Pilger, Sonja J Gill, Kunzah Jamal, Natacha Bohin, Sofia Guzzetti

Clin Cancer Res· April 2024

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Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway.
David Hodson, Hitesh Mistry, Sofia Guzzetti, Michael Davies, Anna Staniszewska

CPT Pharmacometrics Syst Pharmacol· November 2023

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An integrated modelling approach for targeted degradation: insights on optimization, data requirements and PKPD predictions from semi- or fully-mechanistic models and exact steady state solutions.
Sofia Guzzetti, Pablo Morentin Gutierrez

J Pharmacokinet Pharmacodyn· October 2023

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Radiation in Combination with Immune Checkpoint Blockade and DNA Damage Response Inhibitors in Mice: Dosage Optimization in MC38 Syngeneic Tumors via Modelling and Simulation.
David Hodson, Hitesh Mistry, James Yates, Paul Farrington, Anna Staniszewska, Sofia Guzzetti

J Pharmacol Exp Ther· October 2023

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