Publications by authors named "Somnath Mahapatra"

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TRIM63 Overexpression in FISH-Negative MiTF Family Altered Renal Cell Carcinoma (MiTF RCC).
Rahul Mannan, Ying-Bei Chen, Xiaoming Wang, Yuping Zhang, Noshad Hosseini, Somnath Mahapatra

Mod Pathol· November 2025

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Solid-Supported Synthesis of Azine-Bridged Unsymmetrically Functionalized Ferrocenyl Architecture, Device Fabrication, and Sensing of Toxic Agents in Aqueous Medium and Gas Phase.
Biplob Halder, Madhusri Jana, Akriti Bhutia, Sougata Kumar Kar, Somnath Mahapatra

Chem Asian J· November 2025

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Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer.
Jie Luo, Zhixiang Chen, Yuanyuan Qiao, Jean Ching-Yi Tien, Eleanor Young, Somnath Mahapatra

Nat Genet· October 2025

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Divergent FOXA1 mutations drive prostate tumorigenesis and therapy-resistant cellular plasticity.
Sanjana Eyunni, Rahul Mannan, Yuping Zhang, Eleanor Young, Qiuyang Zhang, Somnath Mahapatra

Science· September 2025

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Cellular cartography reveals mouse prostate organization and determinants of castration resistance.
Hanbyul Cho, Yuping Zhang, Jean C Tien, Rahul Mannan, Jie Luo, Somnath Mahapatra

Proc Natl Acad Sci U S A· September 2025

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CDK12/13 inactivation triggers STING-mediated antitumor immunity in preclinical models.
Yi Bao, Yu Chang, Jean Ching-Yi Tien, Gabriel Cruz, Fan Yang, Somnath Mahapatra

J Clin Invest· September 2025

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Targeting PIKfyve-driven lipid metabolism in pancreatic cancer.
Caleb Cheng, Jing Hu, Rahul Mannan, Tongchen He, Rupam Bhattacharyya, Somnath Mahapatra

Nature· June 2025

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Defining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma.
Jean Ching-Yi Tien, Yali Zhai, Rong Wu, Yuping Zhang, Yu Chang, Somnath Mahapatra

Proc Natl Acad Sci U S A· June 2025

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Discovery of : A Potent and Highly Selective Irreversible CDK12/13 Inhibitor with Synergistic Effects in Combination with Akt Inhibition.
Jianzhang Yang, Yu Chang, Kaijie Zhou, Weixue Huang, Jean Ching-Yi Tien, Somnath Mahapatra

J Med Chem· March 2025

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The UBA1-STUB1 Axis Mediates Cancer Immune Escape and Resistance to Checkpoint Blockade.
Yi Bao, Gabriel Cruz, Yuping Zhang, Yuanyuan Qiao, Rahul Mannan, Somnath Mahapatra

Cancer Discov· February 2025

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Cellular cartography reveals mouse prostate organization and determinants of castration resistance.
Hanbyul Cho, Yuping Zhang, Jean C Tien, Rahul Mannan, Jie Luo, Somnath Mahapatra

bioRxiv· December 2024

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NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis.
Abhijit Parolia, Sanjana Eyunni, Brijesh Kumar Verma, Eleanor Young, Yihan Liu, Somnath Mahapatra

Nat Genet· October 2024

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Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition.
Yu Chang, Xiaoju Wang, Jianzhang Yang, Jean Ching-Yi Tien, Rahul Mannan, Somnath Mahapatra

Cell Rep Med· October 2024

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CDK12 loss drives prostate cancer progression, transcription-replication conflicts, and synthetic lethality with paralog CDK13.
Jean Ching-Yi Tien, Jie Luo, Yu Chang, Yuping Zhang, Yunhui Cheng, Somnath Mahapatra

Cell Rep Med· October 2024

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Discovery of ZLC491 as a Potent, Selective, and Orally Bioavailable CDK12/13 PROTAC Degrader.
Licheng Zhou, Kaijie Zhou, Yu Chang, Jianzhang Yang, Bohai Fan, Somnath Mahapatra

J Med Chem· October 2024

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Clinically Relevant Humanized Mouse Models of Metastatic Prostate Cancer Facilitate Therapeutic Evaluation.
Raymond J Kostlan, John T Phoenix, Audris Budreika, Marina G Ferrari, Neetika Khurana, Somnath Mahapatra

Mol Cancer Res· September 2024

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Expression of L1 Cell Adhesion Molecule, a Nephronal Principal Cell Marker, in Nephrogenic Adenoma.
Rahul Mannan, Xiaoming Wang, Somnath Mahapatra, Susanna Wang, Anya K Chinnaiyan

Mod Pathol· August 2024

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Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies.
Tongchen He, Lanbo Xiao, Yuanyuan Qiao, Olaf Klingbeil, Eleanor Young, Somnath Mahapatra

Cancer Cell· August 2024

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Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies.
Tongchen He, Lanbo Xiao, Yuanyuan Qiao, Olaf Klingbeil, Eleanor Young, Somnath Mahapatra

bioRxiv· May 2024

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p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer.
Jie Luo, Zhixiang Chen, Yuanyuan Qiao, Jean Ching-Yi Tien, Eleanor Young, Somnath Mahapatra

bioRxiv· May 2024

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Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer.
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Somnath Mahapatra

Proc Natl Acad Sci U S A· April 2024

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Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer.
Tongchen He, Caleb Cheng, Yuanyuan Qiao, Hanbyul Cho, Eleanor Young, Somnath Mahapatra

bioRxiv· March 2024

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Bleeding with vascular endothelial growth factor tyrosine kinase inhibitor: A network meta-analysis.
Avash Das, Somnath Mahapatra, Dhrubajyoti Bandyopadhyay, Santanu Samanta, Sandipan Chakraborty

Crit Rev Oncol Hematol· January 2021

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Retinal Nerve Fibre Layer Thinning in Patients with Thalassaemia, Iron Deficiency Anaemia, and Anaemia of Chronic Diseases.
Suhana Datta, Krishnapada Baidya, Madhumita Banerjee, Somnath Mahapatra, Sudeb Mukherjee

J Ophthalmol· November 2020

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