Publications by authors named "Sondra L Downey"

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Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells.
Robert J Allaway, Matthew D Wood, Sondra L Downey, Stephanie J Bouley, Nicole A Traphagen

Oncotarget· March 2018

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Use of proteasome inhibitors.
Sondra L Downey, Bogdan I Florea, Herman S Overkleeft, Alexei F Kisselev

Curr Protoc Immunol· April 2015

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Cell-line-specific high background in the Proteasome-Glo assay of proteasome trypsin-like activity.
Owen M Wilkins, Sondra L Downey, Emily S Weyburne, David A Williams, Anne C Mirabella

Anal Biochem· April 2014

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Molecular basis of differential sensitivity of myeloma cells to clinically relevant bolus treatment with bortezomib.
Tamer B Shabaneh, Sondra L Downey, Ayrton L Goddard, Michael Screen, Marcella M Lucas

PLoS One· September 2013

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Phosphorylation of ΔNp63α via a novel TGFβ/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGFβ.
Pratima Cherukuri, Andrew J DeCastro, Amanda L Balboni, Sondra L Downey, Jennifer Y Liu

PLoS One· April 2013

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Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib.
Anne C Mirabella, Alexandre A Pletnev, Sondra L Downey, Bogdan I Florea, Tamer B Shabaneh

Chem Biol· May 2011

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Nature of pharmacophore influences active site specificity of proteasome inhibitors.
Michael Screen, Matthew Britton, Sondra L Downey, Martijn Verdoes, Mathias J Voges

J Biol Chem· December 2010

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Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites.
Paul P Geurink, Nora Liu, Michiel P Spaans, Sondra L Downey, Adrianus M C H van den Nieuwendijk

J Med Chem· March 2010

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Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites.
Matthew Britton, Marcella M Lucas, Sondra L Downey, Michael Screen, Alexandre A Pletnev

Chem Biol· December 2009

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