Publications by authors named "Song-Iee Han"

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Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia.
Yasuhisa Furuta, Yoshinori Osaki, Yoshimi Nakagawa, Song-Iee Han, Masaya Araki

J Atheroscler Thromb· September 2024

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Single-Cell Transcriptome Profiling of Pancreatic Islets From Early Diabetic Mice Identifies Anxa10 for Ca2+ Allostasis Toward β-Cell Failure.
Kaori Motomura, Takashi Matsuzaka, Shigeyuki Shichino, Tatsuro Ogawa, Hao Pan, Song-Iee Han

Diabetes· January 2024

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Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids.
Song-Iee Han, Masanori Nakakuki, Yoshimi Nakagawa, Yunong Wang, Masaya Araki

PNAS Nexus· November 2023

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Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity.
Kenji Saito, Motohiro Sekiya, Kenta Kainoh, Ryunosuke Yoshino, Akio Hayashi, Song-Iee Han

J Biol Chem· July 2023

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Identification of key microRNAs regulating and glioblastoma tumorigenesis.
Nurani Istiqamah, Takashi Matsuzaka, Momo Shimizu, Kaori Motomura, Hiroshi Ohno, Song-Iee Han

BBA Adv· January 2023

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Hepatocyte- or macrophage-specific SREBP-1a deficiency in mice exacerbates methionine- and choline-deficient diet-induced nonalcoholic fatty liver disease.
Masaya Araki, Yoshimi Nakagawa, Hodaka Saito, Yasunari Yamada, Song-Iee Han

Am J Physiol Gastrointest Liver Physiol· December 2022

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Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance is impaired in diabetic db/db mice.
Yuka Okajima, Takashi Matsuzaka, Shun Miyazaki, Kaori Motomura, Hiroshi Ohno, Song-Iee Han

Biochim Biophys Acta Mol Basis Dis· April 2022

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Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition.
Yoshimi Nakagawa, Yunong Wang, Song-Iee Han, Kanako Okuda, Asayo Oishi

Cell Mol Gastroenterol Hepatol· March 2022

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Protocol for rapid manipulation of mitochondrial morphology in living cells using inducible counter mitochondrial morphology (iCMM).
Takafumi Miyamoto, Song-Iee Han, Hitoshi Shimano

STAR Protoc· September 2021

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CREBH Systemically Regulates Lipid Metabolism by Modulating and Integrating Cellular Functions.
Yoshimi Nakagawa, Masaya Araki, Song-Iee Han, Yuhei Mizunoe, Hitoshi Shimano

Nutrients· September 2021

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Rapid manipulation of mitochondrial morphology in a living cell with iCMM.
Takafumi Miyamoto, Hideki Uosaki, Yuhei Mizunoe, Song-Iee Han, Satoi Goto

Cell Rep Methods· August 2021

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Starvation-induced transcription factor CREBH negatively governs body growth by controlling GH signaling.
Yoshimi Nakagawa, Kae Kumagai, Song-Iee Han, Yuhei Mizunoe, Masaya Araki

FASEB J· June 2021

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Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice.
Takashi Matsuzaka, Motoko Kuba, Saori Koyasu, Yuta Yamamoto, Kaori Motomura, Song-Iee Han

Hepatology· May 2020

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CREBH Improves Diet-Induced Obesity, Insulin Resistance, and Metabolic Disturbances by FGF21-Dependent and FGF21-Independent Mechanisms.
Aoi Satoh, Song-Iee Han, Masaya Araki, Yoshimi Nakagawa, Hiroshi Ohno

iScience· March 2020

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Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism.
Rahul Sharma, Takashi Matsuzaka, Mahesh K Kaushik, Takehito Sugasawa, Hiroshi Ohno, Song-Iee Han

Sci Rep· March 2019

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The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice.
Masaya Araki, Yoshimi Nakagawa, Asayo Oishi, Song-Iee Han, Yunong Wang

Int J Mol Sci· July 2018

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Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.
Hiroshi Ohno, Takashi Matsuzaka, Nie Tang, Rahul Sharma, Kaori Motomura, Song-Iee Han

Endocrinology· June 2018

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Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα.
Yuta Yamamoto, Kenta Takei, Sundaram Arulmozhiraja, Vladimir Sladek, Naoya Matsuo, Song-Iee Han

Biochem Biophys Res Commun· May 2018

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Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice.
Noriko Suzuki-Kemuriyama, Takashi Matsuzaka, Motoko Kuba, Hiroshi Ohno, Song-Iee Han

PLoS One· July 2017

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Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.
Kenta Takei, Song-Iee Han, Yuki Murayama, Aoi Satoh, Fusaka Oikawa

J Diabetes Investig· July 2017

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Elovl6 Deficiency Improves Glycemic Control in Diabetic / Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.
Hui Zhao, Takashi Matsuzaka, Yuta Nakano, Kaori Motomura, Nie Tang, Song-Iee Han

Diabetes· July 2017

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Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice.
Kenta Takei, Yoshimi Nakagawa, Yunong Wang, Song-Iee Han, Aoi Satoh

J Pharmacol Sci· April 2017

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CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.
Yoshimi Nakagawa, Aoi Satoh, Hitomi Tezuka, Song-Iee Han, Kenta Takei

Sci Rep· December 2016

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Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing expression.
Takuya Kikuchi, Kana Orihara, Fusaka Oikawa, Song-Iee Han, Motoko Kuba

Mol Metab· November 2016

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Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system.
Yoshimi Nakagawa, Fusaka Oikawa, Seiya Mizuno, Hiroshi Ohno, Yuka Yagishita, Song-Iee Han

Sci Rep· June 2016

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