Publications by authors named "Sonya Lam"

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Insulin receptor loss impairs mammary tumorigenesis in mice.
Lauren Podmore, Yekaterina Poloz, Catherine Iorio, Samar Mouaaz, Kevin Nixon, Sonya Lam

Cell Rep· November 2023

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Ultrasensitive Detection of NOTCH1 c.7544_7545delCT Mutations in Chronic Lymphocytic Leukemia by Droplet Digital PCR Reveals High Frequency of Subclonal Mutations and Predicts Clinical Outcome in Cases with Trisomy 12.
Catherine Hoofd, Steven J Huang, Samuel Gusscott, Sonya Lam, Rachel Wong

J Mol Diagn· April 2020

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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity.
Vincenzo Giambra, Samuel Gusscott, Deanne Gracias, Raymond Song, Sonya H Lam

Cell Stem Cell· November 2018

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Population-based phase II trial of stereotactic ablative radiotherapy (SABR) for up to 5 oligometastases: SABR-5.
Robert Olson, Mitchell Liu, Alanah Bergman, Sonya Lam, Fred Hsu

BMC Cancer· October 2018

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IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias.
Samuel Gusscott, Catherine E Jenkins, Sonya H Lam, Vincenzo Giambra, Michael Pollak

PLoS One· August 2017

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Metformin Pharmacokinetics in Mouse Tumors: Implications for Human Therapy.
Ryan J O Dowling, Sonya Lam, Christian Bassi, Samar Mouaaz, Ahmed Aman

Cell Metab· April 2016

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CD44 promotes chemoresistance in T-ALL by increased drug efflux.
Catherine Hoofd, Xuehai Wang, Sonya Lam, Catherine Jenkins, Brent Wood

Exp Hematol· March 2016

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Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling.
Vincenzo Giambra, Catherine E Jenkins, Sonya H Lam, Catherine Hoofd, Miriam Belmonte

Blood· June 2015

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Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progression.
Trisha Rao, Jill J Ranger, Harvey W Smith, Sonya H Lam, Lewis Chodosh

Breast Cancer Res· January 2014

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NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.
Vincenzo Giambra, Christopher R Jenkins, Hongfang Wang, Sonya H Lam, Olena O Shevchuk

Nat Med· November 2012

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IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein.
Catherine E Jenkins, Olena O Shevchuk, Vincenzo Giambra, Sonya H Lam, Joan M Carboni

Exp Hematol· September 2012

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Receptor tyrosine kinase signaling favors a protumorigenic state in breast cancer cells by inhibiting the adaptive immune response.
Josie Ursini-Siegel, Sean Cory, Dongmei Zuo, William R Hardy, Elton Rexhepaj, Sonya Lam

Cancer Res· October 2010

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ShcA signalling is essential for tumour progression in mouse models of human breast cancer.
Josie Ursini-Siegel, W Rod Hardy, Dongmei Zuo, Sonya H L Lam, Virginie Sanguin-Gendreau

EMBO J· March 2008

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Distinct ErbB-2 coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles.
Babette Schade, Sonya H L Lam, Daniela Cernea, Virginie Sanguin-Gendreau, Robert D Cardiff

Cancer Res· August 2007

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