Publications by authors named "Souren Mkrtchian"

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Changes in circulating extracellular vesicle cargo are associated with cognitive decline after major surgery: an observational case-control study.
Souren Mkrtchian, Maria Eldh, Anette Ebberyd, Susanne Gabrielsson, Ákos Végvári

Br J Anaesth· June 2025

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Calcium-Regulating Hormonal System and HMGB1 in Cardiomyopathies.
Knarik R Harutyunyan, Hermine T Abrahamyan, Satenik H Adamyan, Souren Mkrtchian, Anna S Ter-Markosyan

Endocr Metab Immune Disord Drug Targets· March 2023

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Surgical Trauma in Mice Modifies the Content of Circulating Extracellular Vesicles.
Souren Mkrtchian, Anette Ebberyd, Rosanne E Veerman, María Méndez-Lago, Susanne Gabrielsson

Front Immunol· March 2022

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Whole blood gene expression signature in patients with obstructive sleep apnea and effect of continuous positive airway pressure treatment.
Eva Christensson, Souren Mkrtchian, Anette Ebberyd, Åsa Österlund Modalen, Karl A Franklin

Respir Physiol Neurobiol· December 2021

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Biomarkers for oxidative stress and organ injury during Transnasal Humidified Rapid-Insufflation Ventilatory Exchange compared to mechanical ventilation in adults undergoing microlaryngoscopy: A randomised controlled study.
Ida-Maria Forsberg, Souren Mkrtchian, Anette Ebberyd, Johan Ullman, Lars I Eriksson

Acta Anaesthesiol Scand· October 2021

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Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine.
Yitian Zhou, Gabriel Herras Arribas, Ainoleena Turku, Tuuli Jürgenson, Souren Mkrtchian

Sci Adv· September 2021

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Can the calcium-regulating hormones counteract the detrimental impact of pro-inflammatory damage-associated molecular patterns in the development of heart failure?
Satenik H Adamyan, Knarik R Harutyunyan, Hermine T Abrahamyan, Drastamat N Khudaverdyan, Souren Mkrtchian

J Investig Med· August 2021

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Association between cerebrospinal fluid biomarkers of neuronal injury or amyloidosis and cognitive decline after major surgery.
Mattias Danielson, Andreas Wiklund, Fredrik Granath, Kaj Blennow, Souren Mkrtchian

Br J Anaesth· February 2021

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The impact of damage-associated molecular patterns on the neurotransmitter release and gene expression in the ex vivo rat carotid body.
Souren Mkrtchian, Jessica Kåhlin, Marta Gómez-Galán, Anette Ebberyd, Takashi Yoshitake

Exp Physiol· September 2020

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Neuroinflammatory markers associate with cognitive decline after major surgery: Findings of an explorative study.
Mattias Danielson, Andreas Wiklund, Fredrik Granath, Kaj Blennow, Souren Mkrtchian

Ann Neurol· March 2020

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Hypoxia Regulates MicroRNA Expression in the Human Carotid Body.
Souren Mkrtchian, Kian Leong Lee, Jessica Kåhlin, Anette Ebberyd, Lorenz Poellinger

Adv Exp Med Biol· July 2019

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An optimized prediction framework to assess the functional impact of pharmacogenetic variants.
Yitian Zhou, Souren Mkrtchian, Masaki Kumondai, Masahiro Hiratsuka, Volker M Lauschke

Pharmacogenomics J· April 2019

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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data.
Yitian Zhou, Kohei Fujikura, Souren Mkrtchian, Volker M Lauschke

Front Pharmacol· December 2018

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Calcium Signaling in Liver Injury and Regeneration.
Nuria Oliva-Vilarnau, Simona Hankeova, Sabine U Vorrink, Souren Mkrtchian, Emma R Andersson

Front Med (Lausanne)· July 2018

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Integrating rare genetic variants into pharmacogenetic drug response predictions.
Magnus Ingelman-Sundberg, Souren Mkrtchian, Yitian Zhou, Volker M Lauschke

Hum Genomics· May 2018

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Hypoxia regulates microRNA expression in the human carotid body.
Souren Mkrtchian, Kian Leong Lee, Jessica Kåhlin, Anette Ebberyd, Lorenz Poellinger

Exp Cell Res· March 2017

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The role of microRNAs in liver injury at the crossroad between hepatic cell death and regeneration.
Volker M Lauschke, Souren Mkrtchian, Magnus Ingelman-Sundberg

Biochem Biophys Res Commun· January 2017

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Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation.
Volker M Lauschke, Sabine U Vorrink, Sabrina M L Moro, Fatemah Rezayee, Åsa Nordling, Souren Mkrtchian

Hepatology· November 2016

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Sedation with Dexmedetomidine or Propofol Impairs Hypoxic Control of Breathing in Healthy Male Volunteers: A Nonblinded, Randomized Crossover Study.
Åse Lodenius, Anette Ebberyd, Anna Hårdemark Cedborg, Eva Hagel, Souren Mkrtchian

Anesthesiology· October 2016

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The CYP2W1 enzyme: regulation, properties and activation of prodrugs.
Jia Guo, Inger Johansson, Souren Mkrtchian, Magnus Ingelman-Sundberg

Drug Metab Rev· August 2016

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Expression and Function of mARC: Roles in Lipogenesis and Metabolic Activation of Ximelagatran.
Etienne P A Neve, Harald Köfeler, Delilah F G Hendriks, Åsa Nordling, Vladimir Gogvadze, Souren Mkrtchian

PLoS One· May 2016

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Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
Catherine C Bell, Delilah F G Hendriks, Sabrina M L Moro, Ewa Ellis, Joanne Walsh, Souren Mkrtchian

Sci Rep· May 2016

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Developmental regulation and induction of cytochrome P450 2W1, an enzyme expressed in colon tumors.
Eva Choong, Jia Guo, Anna Persson, Susanne Virding, Inger Johansson, Souren Mkrtchian

PLoS One· April 2016

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Membrane topology and search for potential redox partners of colon cancer-specific cytochrome P450 2W1.
Jia Guo, Stefanie Thiess, Inger Johansson, Souren Mkrtchian, Magnus Ingelman-Sundberg

FEBS Lett· February 2016

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The Human Carotid Body Gene Expression and Function in Signaling of Hypoxia and Inflammation.
Jessica Kåhlin, Souren Mkrtchian, Anette Ebberyd, Lars I Eriksson, Malin Jonsson Fagerlund

Adv Exp Med Biol· January 2016

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