Publications by authors named "Srinivas Akula"

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Recirculating glass pipettes constitute a high risk when working with freshly isolated immune cells - the presence of bacterial pyrogenic material.
Srinivas Akula, Sandra Lara, Anna-Karin Olsson, Lars Hellman

Front Cell Infect Microbiol· December 2025

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"Smart agriculture: a climate-driven approach to modelling and forecasting fall armyworm populations in maize using machine learning algorithms".
Vani Sree Kalisetti, Upendhar Sudharshanam, Nagesh Kumar Mallela Venkata, Rajashekhar Mandla, Srinivas Akula

Front Plant Sci· November 2025

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Exploring a pico-well based scRNA-seq method (HIVE) for simplified processing of equine bronchoalveolar lavage cells.
Kim Fegraeus, Miia Riihimäki, Jessica Nordlund, Srinivas Akula, Sara Wernersson

PLoS One· May 2025

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Targeting carboxypeptidase A/B activity with the phosphinic inhibitor C28 reduces the asthmatic response in a mouse model of house dust mite-induced asthma.
Venkata Sita Rama Raju Allam, David Montpeyó, Fabrice Beau, Sowsan Taha, Ida Waern, Srinivas Akula

Inflamm Res· May 2025

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Monensin Suppresses Multiple Features of House Dust Mite-Induced Experimental Asthma in Mice.
Venkata Sita Rama Raju Allam, Srinivas Akula, Ida Waern, Sowsan Taha, Sara Wernersson

Inflammation· April 2025

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Characterization of Freshly Isolated Human Peripheral Blood B Cells, Monocytes, CD4+ and CD8+ T Cells, and Skin Mast Cells by Quantitative Transcriptomics.
Srinivas Akula, Abigail Alvarado-Vazquez, Erika Haide Mendez Enriquez, Gürkan Bal, Kristin Franke

Int J Mol Sci· December 2024

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Disruption of the mast cell carboxypeptidase A3 gene does not attenuate airway inflammation and hyperresponsiveness in two mouse models of asthma.
Ida Waern, Srinivas Akula, Venkata Sita Rama Raju Allam, Sowsan Taha, Thorsten B Feyerabend

PLoS One· April 2024

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Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology.
Srinivas Akula, Shiva Raj Tripathi, Kristin Franke, Sara Wernersson, Magda Babina

Cells· January 2024

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Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar ().
Paolo Valentini, Srinivas Akula, Abigail Alvarado-Vazquez, Jenny Hallgren, Zhirong Fu

Int J Mol Sci· January 2024

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The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells.
Michael Thorpe, Srinivas Akula, Zhirong Fu, Lars Hellman

Int J Mol Sci· December 2023

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Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity.
Erdem Aybay, Mamoun Elkhalifa, Srinivas Akula, Sara Wernersson, Lars Hellman

Dev Comp Immunol· November 2023

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Identification of the Major Protein Components of Human and Cow Saliva.
Srinivas Akula, Charlotte Welinder, Zhirong Fu, Anna-Karin Olsson, Lars Hellman

Int J Mol Sci· November 2023

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Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma.
Miia Riihimäki, Kim Fegraeus, Jessica Nordlund, Ida Waern, Sara Wernersson, Srinivas Akula

Sci Rep· September 2023

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Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity.
Erdem Aybay, Jinhye Ryu, Zhirong Fu, Srinivas Akula, Erika Mendez Enriquez

Front Immunol· July 2023

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Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity.
Venkata Sita Rama Raju Allam, Ida Waern, Sowsan Taha, Srinivas Akula, Sara Wernersson

Front Immunol· May 2023

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Quantitative Transcriptome Analysis of Purified Equine Mast Cells Identifies a Dominant Mucosal Mast Cell Population with Possible Inflammatory Functions in Airways of Asthmatic Horses.
Srinivas Akula, Miia Riihimäki, Ida Waern, Magnus Åbrink, Amanda Raine

Int J Mol Sci· November 2022

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Mast Cell and Basophil Granule Proteases - Targets and Function.
Lars Hellman, Srinivas Akula, Zhirong Fu, Sara Wernersson

Front Immunol· July 2022

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Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation.
Srinivas Akula, Sandra Lara, Anna-Karin Olsson, Lars Hellman

Int J Mol Sci· May 2022

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Chicken cathepsin G-like - A highly specific serine protease with a peculiar tryptase specificity expressed by chicken thrombocytes.
Zhirong Fu, Srinivas Akula, Anna-Karin Olsson, Lars Hellman

Dev Comp Immunol· April 2022

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Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases.
Jinhye Ryu, Zhirong Fu, Srinivas Akula, Anna-Karin Olsson, Lars Hellman

Dev Comp Immunol· March 2022

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The Human Monocyte-A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation.
Sandra Lara, Srinivas Akula, Zhirong Fu, Anna-Karin Olsson, Sandra Kleinau

Int J Mol Sci· March 2022

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Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems.
Aida Paivandy, Srinivas Akula, Sandra Lara, Zhirong Fu, Anna-Karin Olsson

Int J Mol Sci· January 2022

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Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases.
Zhirong Fu, Srinivas Akula, Anna-Karin Olsson, Jukka Kervinen, Lars Hellman

Int J Mol Sci· November 2021

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The Evolutionary History of the -a Locus Encoding Several of the Major Hematopoietic Serine Proteases.
Srinivas Akula, Zhirong Fu, Sara Wernersson, Lars Hellman

Int J Mol Sci· October 2021

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Putative role of prosthetic dental implants in the development of cardiac sarcoidosis: A case-control study.
Muthiah Subramanian, Debabrata Bera, Jospeh Theodore, Jugal Kishore, Akula Srinivas

Sarcoidosis Vasc Diffuse Lung Dis· September 2021

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