Publications by authors named "Srinivas Chatla"

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ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination.
Huan Li, Srinivas Chatla, Xiaolei Liu, Zhen Tian, Umeshkumar Vekariya

Cancer Lett· March 2025

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R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription-Replication Conflicts.
Zhiyan Silvia Liu, Sayantani Sinha, Maxwell Bannister, Axia Song, Erica Arriaga-Gomez, Srinivas Chatla

Cancer Res· February 2024

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LepR+ niche cell-derived AREG compromises hematopoietic stem cell maintenance under conditions of DNA repair deficiency and aging.
Limei Wu, Qiqi Lin, Srinivas Chatla, Surya Amarachintha, Andrew F Wilson

Blood· November 2023

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DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Umeshkumar Vekariya, Monika Toma, Margaret Nieborowska-Skorska, Bac Viet Le, Marie-Christine Caron, Srinivas Chatla

Blood· May 2023

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Haploinsufficiency of ZNF251 causes DNA-PKcs-dependent resistance to PARP inhibitors in BRCA1-mutated cancer cells.
Huan Li, Srinivas Chatla, Xiaolei Liu, Umeshkumar Vekariya, Dongwook Kim

Res Sq· April 2023

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ABL1 kinase as a tumor suppressor in AML1-ETO and NUP98-PMX1 leukemias.
Konstantin Golovine, Gleb Abalakov, Zhaorui Lian, Srinivas Chatla, Adam Karami

Blood Cancer J· March 2023

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Persistent DNA damage and oncogenic stress-induced Trem1 promotes leukemia in mice.
Xue Li, Srinivas Chatla, Andrew F Wilson, Limei Wu, Neha Atale

Haematologica· November 2022

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Hematopoietic stem cell regeneration through paracrine regulation of the Wnt5a/Prox1 signaling axis.
Qiqi Lin, Limei Wu, Srinivas Chatla, Fabliha A Chowdhury, Neha Atale

J Clin Invest· June 2022

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Quinacrine-CASIN combination overcomes chemoresistance in human acute lymphoid leukemia.
Limei Wu, Srinivas Chatla, Qiqi Lin, Fabliha Ahmed Chowdhury, Werner Geldenhuys

Nat Commun· November 2021

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Inactivation of the NHEJ Activity of DNA-PKcs Prevents Fanconi Anemia Pre-Leukemic HSC Expansion.
Srinivas Chatla, Andrew F Wilson, Qishen Pang

Int J Stem Cells· November 2019

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Fancd2-deficient hematopoietic stem and progenitor cells depend on augmented mitochondrial translation for survival and proliferation.
Srinivas Chatla, Wei Du, Andrew F Wilson, Amom Ruhikanta Meetei, Qishen Pang

Stem Cell Res· October 2019

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Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer.
Sushil Kumar, Ratnesh Kumar Srivastav, David W Wilkes, Taylor Ross, Sabrina Kim, Srinivas Chatla

Oncogene· March 2019

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Scriptaid cause histone deacetylase inhibition and cell cycle arrest in HeLa cancer cells: A study on structural and functional aspects.
M Janaki Ramaiah, Shaik Mohammad Naushad, A Lavanya, Chatla Srinivas, Tangutur Anjana Devi

Gene· September 2017

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Novel SAHA analogues inhibit HDACs, induce apoptosis and modulate the expression of microRNAs in hepatocellular carcinoma.
Chatla Srinivas, V Swathi, C Priyanka, T Anjana Devi, B V Subba Reddy

Apoptosis· November 2016

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Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer.
Chatla Srinivas, M Janaki Ramaiah, A Lavanya, Suresh Yerramsetty, P B Kavi Kishor

PLoS One· July 2016

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aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle.
Srivari Chandrasekhar, Sreerangam N C V L Pushpavalli, Srinivas Chatla, Debasmita Mukhopadhyay, Bogonda Ganganna

Bioorg Med Chem Lett· January 2012

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Synthesis of imidazothiazole-chalcone derivatives as anticancer and apoptosis inducing agents.
Ahmed Kamal, D Dastagiri, M Janaki Ramaiah, J Surendranadha Reddy, E Vijaya Bharathi, Chatla Srinivas

ChemMedChem· November 2010

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Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole-pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
Ahmed Kamal, K Srinivasa Reddy, M Naseer A Khan, Rajesh V C R N C Shetti, M Janaki Ramaiah, Chatla Srinivas

Bioorg Med Chem· July 2010

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