Publications by authors named "Stacey R Dillon"

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Povetacicept (ALPN-303; TACI vTD-Fc), an enhanced, potent dual inhibitor of BAFF and APRIL, ameliorates experimental autoimmune myasthenia gravis in C57BL/6N mice.
Elena Rinaldi, Elisa Puleo, Alessandra Consonni, Martina Miglietti, Renato Mantegazza, Stacey R Dillon

Front Immunol· June 2025

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A first-in-human, randomized study of the safety, pharmacokinetics and pharmacodynamics of povetacicept, an enhanced dual BAFF/APRIL antagonist, in healthy adults.
Rupert Davies, Stanford L Peng, Jason Lickliter, Kristi McLendon, Amanda Enstrom, Stacey R Dillon

Clin Transl Sci· November 2024

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Non-Redundant Roles of T Cell Costimulation Pathways in Inflammatory Arthritis Revealed by Dual Blockade of ICOS and CD28 with Acazicolcept (ALPN-101).
Stacey R Dillon, Lawrence S Evans, Katherine E Lewis, Susan Debrot, Tiffany C Blair

Arthritis Rheumatol· August 2023

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Povetacicept, an Enhanced Dual APRIL/BAFF Antagonist That Modulates B Lymphocytes and Pathogenic Autoantibodies for the Treatment of Lupus and Other B Cell-Related Autoimmune Diseases.
Lawrence S Evans, Katherine E Lewis, Daniel DeMonte, Janhavi G Bhandari, Logan B Garrett, Stacey R Dillon

Arthritis Rheumatol· July 2023

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Systemic Administration of Acazicolcept, a Dual CD28 and Inducible T cell Costimulator Inhibitor, Ameliorates Experimental Autoimmune Uveitis.
Leslie Wilson, Katherine E Lewis, Lawrence S Evans, Stacey R Dillon, Kathryn L Pepple

Transl Vis Sci Technol· March 2023

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The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.
Mark F Maurer, Katherine E Lewis, Joseph L Kuijper, Dan Ardourel, Chelsea J Gudgeon, Stacey R Dillon

Nat Commun· April 2022

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Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models.
Cindy Orvain, Anne Cauvet, Alexis Prudent, Christophe Guignabert, Raphaël Thuillet, Stacey R Dillon

Arthritis Res Ther· January 2022

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IL-31 transgenic mice show reduced allergen-induced lung inflammation.
Theresa Neuper, Daniel Neureiter, Muamera Sarajlic, Helen Strandt, Renate Bauer, Stacey R Dillon

Eur J Immunol· January 2021

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Novel Immunomodulatory Proteins Generated via Directed Evolution of Variant IgSF Domains.
Steven D Levin, Lawrence S Evans, Susan Bort, Erika Rickel, Katherine E Lewis, Stacey R Dillon

Front Immunol· November 2020

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ICOSL plasmacytoid dendritic cells as inducer of graft-versus-host disease, responsive to a dual ICOS/CD28 antagonist.
Djamilatou Adom, Stacey R Dillon, Jinfeng Yang, Hao Liu, Abdulraouf Ramadan

Sci Transl Med· October 2020

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Conditioned media from the renal cell carcinoma cell line 786.O drives human blood monocytes to a monocytic myeloid-derived suppressor cell phenotype.
Shannon L Okada, Randi M Simmons, Secil Franke-Welch, Thuy H Nguyen, Alan J Korman, Stacey R Dillon

Cell Immunol· January 2018

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Interleukin-21 combined with PD-1 or CTLA-4 blockade enhances antitumor immunity in mouse tumor models.
Katherine E Lewis, Mark J Selby, Gregg Masters, Jose Valle, Gennaro Dito, Stacey R Dillon

Oncoimmunology· October 2017

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IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function.
Brijendra Singh, Anil G Jegga, Kumar S Shanmukhappa, Ramakrishna Edukulla, Gurjit H Khurana Hershey, Stacey R Dillon

PLoS One· July 2017

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Correction: IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function.
Brijendra Singh, Anil G Jegga, Kumar S Shanmukhappa, Ramakrishna Edukulla, Gurjit Kaur Khurana Hershey, Stacey R Dillon

PLoS One· January 2017

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The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves.
Micha Feld, Richard Garcia, Jörg Buddenkotte, Shintaro Katayama, Katherine Lewis, Stacey R Dillon

J Allergy Clin Immunol· August 2016

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RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications.
Mayte Suárez-Fariñas, Benjamin Ungar, Joel Correa da Rosa, David A Ewald, Mariya Rozenblit, Stacey R Dillon

J Allergy Clin Immunol· May 2015

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Th2 Cytokines Augment IL-31/IL-31RA Interactions via STAT6-dependent IL-31RA Expression.
Ramakrishna Edukulla, Brijendra Singh, Anil G Jegga, Vishwaraj Sontake, Stacey R Dillon

J Biol Chem· May 2015

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A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1.
Ferda Cevikbas, Xidao Wang, Tasuku Akiyama, Cordula Kempkes, Terhi Savinko, Stacey R Dillon

J Allergy Clin Immunol· February 2014

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Serum from patients with SLE instructs monocytes to promote IgG and IgA plasmablast differentiation.
Hyemee Joo, Christine Coquery, Yaming Xue, Ingrid Gayet, Stacey R Dillon

J Exp Med· July 2012

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Generation and characterization of human anti-human IL-21 neutralizing monoclonal antibodies.
Mark F Maurer, Ursula Garrigues, Stephen R Jaspers, Brent Meengs, Mark W Rixon, Stacey R Dillon

MAbs· June 2012

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Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L.
Montserrat Cols, Carolina M Barra, Bing He, Irene Puga, Weifeng Xu, Stacey R Dillon

J Immunol· June 2012

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IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis.
Stephan Nobbe, Piotr Dziunycz, Beda Mühleisen, Janine Bilsborough, Stacey R Dillon

Acta Derm Venereol· January 2012

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Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes.
Keli L Hippen, Christoph Bucher, Dawn K Schirm, Amanda M Bearl, Ty Brender, Stacey R Dillon

Blood· January 2012

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Toll-like receptor 9, transmembrane activator and calcium-modulating cyclophilin ligand interactor, and CD40 synergize in causing B-cell activation.
Esra Ozcan, Ingrid Rauter, Lilit Garibyan, Stacey R Dillon, Raif S Geha

J Allergy Clin Immunol· September 2011

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Functional analysis of transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) mutations associated with common variable immunodeficiency.
Ari J Fried, Ingrid Rauter, Stacey R Dillon, Haifa H Jabara, Raif S Geha

J Allergy Clin Immunol· July 2011

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