Publications by authors named "Stan Gaj"

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A phase 1, first-in-human, dose-escalation study of JNJ-74856665 (dihydroorotate dehydrogenase inhibitor) alone or in combination in patients with AML or MDS.
Emma Searle, Thomas Cluzeau, Jenny O'Nions, Christian Recher, Emmanuel Gyan, Stan Gaj

Br J Haematol· July 2025

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Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis.
Simone G J van Breda, Sandra M H Claessen, Ken Lo, Marcel van Herwijnen, Karen J J Brauers, Stan Gaj

Arch Toxicol· November 2015

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The exposome concept in a human nutrigenomics study: evaluating the impact of exposure to a complex mixture of phytochemicals using transcriptomics signatures.
Simone G J van Breda, Lonneke C Wilms, Stan Gaj, Danyel G J Jennen, Jacob J Briedé

Mutagenesis· November 2015

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Integrating multiple omics to unravel mechanisms of Cyclosporin A induced hepatotoxicity in vitro.
Wim F P M Van den Hof, Ainhoa Ruiz-Aracama, Anke Van Summeren, Danyel G J Jennen, Stan Gaj

Toxicol In Vitro· April 2015

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High-throughput data integration of RNA-miRNA-circRNA reveals novel insights into mechanisms of benzo[a]pyrene-induced carcinogenicity.
Florian Caiment, Stan Gaj, Sandra Claessen, Jos Kleinjans

Nucleic Acids Res· March 2015

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Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicity.
Dennie G A Hebels, Marlon J A Jetten, Hugo J W Aerts, Ralf Herwig, Daniël H J Theunissen, Stan Gaj

Biomark Med· October 2014

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The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance.
Charles Wang, Binsheng Gong, Pierre R Bushel, Jean Thierry-Mieg, Danielle Thierry-Mieg, Stan Gaj

Nat Biotechnol· September 2014

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Can transcriptomics provide insight into the chemopreventive mechanisms of complex mixtures of phytochemicals in humans?
Simone G J van Breda, Lonneke C Wilms, Stan Gaj, Danyel G J Jennen, Jacob J Briedé

Antioxid Redox Signal· May 2014

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User-friendly solutions for microarray quality control and pre-processing on ArrayAnalysis.org.
Lars M T Eijssen, Magali Jaillard, Michiel E Adriaens, Stan Gaj, Philip J de Groot

Nucleic Acids Res· July 2013

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RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene.
Joost van Delft, Stan Gaj, Matthias Lienhard, Marcus W Albrecht, Alexander Kirpiy

Toxicol Sci· December 2012

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GO-Elite: a flexible solution for pathway and ontology over-representation.
Alexander C Zambon, Stan Gaj, Isaac Ho, Kristina Hanspers, Karen Vranizan

Bioinformatics· August 2012

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Benzo[a]pyrene-induced changes in microRNA-mRNA networks.
Daneida Lizarraga, Stan Gaj, Karen J Brauers, Leen Timmermans, Jos C Kleinjans

Chem Res Toxicol· April 2012

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'Omics analysis of low dose acetaminophen intake demonstrates novel response pathways in humans.
Marlon J A Jetten, Stan Gaj, Ainhoa Ruiz-Aracama, Theo M de Kok, Joost H M van Delft

Toxicol Appl Pharmacol· March 2012

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Effect of Trichostatin A on miRNA expression in cultures of primary rat hepatocytes.
Jennifer Bolleyn, Joanna Fraczek, Mathieu Vinken, Daneida Lizarraga, Stan Gaj

Toxicol In Vitro· September 2011

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Biotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changes.
Danyel G J Jennen, Stan Gaj, Pieter J Giesbertz, Joost H M van Delft, Chris T Evelo

Drug Discov Today· October 2010

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Reduction of colonic inflammation in HLA-B27 transgenic rats by feeding Marie Ménard apples, rich in polyphenols.
Cinzia Castagnini, Cristina Luceri, Simona Toti, Elisabetta Bigagli, Giovanna Caderni, Stan Gaj

Br J Nutr· December 2009

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Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon.
Anna Kipp, Antje Banning, Evert M van Schothorst, Catherine Méplan, Lutz Schomburg, Stan Gaj

Mol Nutr Food Res· December 2009

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Linking microarray reporters with protein functions.
Stan Gaj, Arie van Erk, Rachel I M van Haaften, Chris T A Evelo

BMC Bioinformatics· September 2007

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