Publications by authors named "Stefan J Steyn"

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A Novel C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) Antagonist (PF-07054894) Distinguishes between Homologous Chemokine Receptors, Increases Basal Circulating CCR6 T Cells, and Ameliorates Interleukin-23-Induced Skin Inflammation.
Wei Li, Kimberly K Crouse, Jennifer Alley, Richard K Frisbie, Susan C Fish, Stefan J Steyn

J Pharmacol Exp Ther· July 2023

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Projecting ADME Behavior and Drug-Drug Interactions in Early Discovery and Development: Application of the Extended Clearance Classification System.
Ayman F El-Kattan, Manthena V Varma, Stefan J Steyn, Dennis O Scott, Tristan S Maurer

Pharm Res· December 2016

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Insights From an Integrated Physiologically Based Pharmacokinetic Model for Brain Penetration.
Patrick E Trapa, Elena Belova, Jenny L Liras, Dennis O Scott, Stefan J Steyn

J Pharm Sci· February 2016

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Biochemical and pharmacological characterization of human c-Met neutralizing monoclonal antibody CE-355621.
Neil R Michaud, Jitesh P Jani, Stephen Hillerman, Konstantinos E Tsaparikos, Elsa G Barbacci-Tobin, Stefan J Steyn

MAbs· January 2014

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PF-03814735, an orally bioavailable small molecule aurora kinase inhibitor for cancer therapy.
Jitesh P Jani, Joel Arcari, Vincent Bernardo, Samit K Bhattacharya, David Briere, Stefan J Steyn

Mol Cancer Ther· April 2010

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High throughput ADME screening: practical considerations, impact on the portfolio and enabler of in silico ADME models.
Cornelis E C A Hop, Mark J Cole, Ralph E Davidson, David B Duignan, James Federico, Stefan J Steyn

Curr Drug Metab· November 2008

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