Publications by authors named "Stefan Rubner"

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Nutlin-3a-aa: Improving the Bioactivity of a p53/MDM2 Interaction Inhibitor by Introducing a Solvent-Exposed Methylene Group.
Florian Nietzold, Stefan Rubner, Beata Labuzek, Przemysław Golik, Ewa Surmiak

Chembiochem· March 2023

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Stafia-1: a STAT5a-Selective Inhibitor Developed via Docking-Based Screening of in Silico O-Phosphorylated Fragments.
Kalaiselvi Natarajan, Daniel Müller-Klieser, Stefan Rubner, Thorsten Berg

Chemistry· January 2020

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The hydrophobically-tagged MDM2-p53 interaction inhibitor Nutlin-3a-HT is more potent against tumor cells than Nutlin-3a.
Florian Nietzold, Stefan Rubner, Thorsten Berg

Chem Commun (Camb)· November 2019

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The STAT5b Linker Domain Mediates the Selectivity of Catechol Bisphosphates for STAT5b over STAT5a.
Julian Gräb, Angela Berg, Linda Blechschmidt, Barbara Klüver, Stefan Rubner

ACS Chem Biol· April 2019

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Poloxin-2HT+: changing the hydrophobic tag of Poloxin-2HT increases Plk1 degradation and apoptosis induction in tumor cells.
Stefan Rubner, Sabine Schubert, Thorsten Berg

Org Biomol Chem· March 2019

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Selective Degradation of Polo-like Kinase 1 by a Hydrophobically Tagged Inhibitor of the Polo-Box Domain.
Stefan Rubner, Andrej Scharow, Sabine Schubert, Thorsten Berg

Angew Chem Int Ed Engl· December 2018

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iSPAAC: Isomer-Free Generation of a Bcl-x -Inhibitor in Living Cells.
Christian Lis, Stefan Rubner, Corinna Gröst, Ralf Hoffmann, Daniel Knappe

Chemistry· September 2018

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Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells.
Christian Lis, Stefan Rubner, Martin Roatsch, Angela Berg, Tyler Gilcrest

Sci Rep· December 2017

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Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes.
Nora Raulien, Kathleen Friedrich, Sarah Strobel, Stefan Rubner, Sven Baumann

Front Immunol· May 2017

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Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b.
Nagarajan Elumalai, Angela Berg, Stefan Rubner, Linda Blechschmidt, Chen Song

Sci Rep· April 2017

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Mimicking Tissue Boundaries by Sharp Multiparameter Matrix Interfaces.
Jiranuwat Sapudom, Stefan Rubner, Steve Martin, Tilo Pompe

Adv Healthc Mater· August 2016

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Phosphorylation of Capsaicinoid Derivatives Provides Highly Potent and Selective Inhibitors of the Transcription Factor STAT5b.
Nagarajan Elumalai, Angela Berg, Stefan Rubner, Thorsten Berg

ACS Chem Biol· December 2015

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The interplay of fibronectin functionalization and TGF-β1 presence on fibroblast proliferation, differentiation and migration in 3D matrices.
Jiranuwat Sapudom, Stefan Rubner, Steve Martin, Stephan Thoenes, Ulf Anderegg

Biomater Sci· September 2015

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The phenotype of cancer cell invasion controlled by fibril diameter and pore size of 3D collagen networks.
Jiranuwat Sapudom, Stefan Rubner, Steve Martin, Tony Kurth, Stefanie Riedel

Biomaterials· June 2015

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