Publications by authors named "Stefania Baraldi"

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Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors.
Romeo Romagnoli, Filippo Prencipe, Paola Oliva, Stefania Baraldi, Pier Giovanni Baraldi

J Med Chem· February 2019

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Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells.
Romeo Romagnoli, Filippo Prencipe, Luisa Carlota Lopez-Cara, Paola Oliva, Stefania Baraldi, Pier Giovanni Baraldi

J Enzyme Inhib Med Chem· December 2018

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3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Romeo Romagnoli, Filippo Prencipe, Paola Oliva, Stefania Baraldi, Pier Giovanni Baraldi

Bioorg Chem· October 2018

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A Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy.
Kenneth A Jacobson, Stefania Merighi, Katia Varani, Pier Andrea Borea, Stefania Baraldi, Pier Giovanni Baraldi

Med Res Rev· July 2018

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Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Stefania Baraldi, Emanuela Ruggiero, Lucia De Stefano

J Med Chem· February 2018

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2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romeo Romagnoli, Maria Kimatrai Salvador, Santiago Schiaffino Ortega, Pier Giovanni Baraldi, Paola Oliva, Stefania Baraldi

Eur J Med Chem· January 2018

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Medicinal Chemistry, Pharmacology, and Clinical Implications of TRPV1 Receptor Antagonists.
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Stefania Baraldi, Stefania Gessi, Stefania Merighi

Med Res Rev· July 2017

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Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents.
Romeo Romagnoli, Pier Giovanni Baraldi, Filippo Prencipe, Paola Oliva, Stefania Baraldi

Eur J Med Chem· July 2017

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Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.
Romeo Romagnoli, Pier Giovanni Baraldi, Filippo Prencipe, Paola Oliva, Stefania Baraldi

Sci Rep· April 2017

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Synthesis and structure activity relationship investigation of triazolo[1,5-a]pyrimidines as CB2 cannabinoid receptor inverse agonists.
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Emanuela Ruggiero, Giulia Saponaro, Stefania Baraldi

Eur J Med Chem· May 2016

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Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole.
Romeo Romagnoli, Pier Giovanni Baraldi, Filippo Prencipe, Paola Oliva, Stefania Baraldi

Sci Rep· May 2016

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Synthesis and Biological Evaluation of Pyrazolo[3,4-b]pyridin-4-ones as a New Class of Topoisomerase II Inhibitors.
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Stefania Baraldi, Filippo Prencipe, Delia Preti

Med Chem· February 2016

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One-pot reaction to obtain N,N'-disubstituted guanidines of pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold as human A3 adenosine receptor antagonists.
Pier Giovanni Baraldi, Stefania Baraldi, Giulia Saponaro, Mojgan Aghazadeh Tabrizi, Romeo Romagnoli

J Med Chem· July 2015

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Pyrazole phenylcyclohexylcarbamates as inhibitors of human fatty acid amide hydrolases (FAAH).
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Emanuela Ruggiero, Giulia Saponaro, Stefania Baraldi

Eur J Med Chem· June 2015

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Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor.
Delia Preti, Pier Giovanni Baraldi, Giulia Saponaro, Romeo Romagnoli, Mojgan Aghazadeh Tabrizi, Stefania Baraldi

J Med Chem· April 2015

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Synthesis and biological evaluation of novel allosteric enhancers of the A1 adenosine receptor based on 2-amino-3-(4'-chlorobenzoyl)-4-substituted-5-arylethynyl thiophene.
Romeo Romagnoli, Pier Giovanni Baraldi, Adriaan P IJzerman, Arnault Massink, Olga Cruz-Lopez, Stefania Baraldi

J Med Chem· September 2014

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Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A₁ adenosine receptor.
Romeo Romagnoli, Pier Giovanni Baraldi, Maria Dora Carrion, Olga Cruz-Lopez, Carlota Lopez Cara, Stefania Baraldi

Bioorg Med Chem· January 2014

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Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB(2) cannabinoid receptor inverse agonists.
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Giulia Saponaro, Allan R Moorman, Romeo Romagnoli, Stefania Baraldi

J Med Chem· June 2013

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Design, synthesis, and pharmacological properties of new heteroarylpyridine/heteroarylpyrimidine derivatives as CB(2) cannabinoid receptor partial agonists.
Mojgan Aghazadeh Tabrizi, Pier Giovanni Baraldi, Giulia Saponaro, Allan R Moorman, Romeo Romagnoli, Stefania Baraldi

J Med Chem· February 2013

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7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as selective CB(2) cannabinoid receptor ligands: structural investigations around a novel class of full agonists.
Pier Giovanni Baraldi, Giulia Saponaro, Allan R Moorman, Romeo Romagnoli, Delia Preti, Stefania Baraldi

J Med Chem· July 2012

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Water-soluble pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as human A₃ adenosine receptor antagonists.
Pier Giovanni Baraldi, Giulia Saponaro, Romeo Romagnoli, Mojgan Aghazadeh Tabrizi, Stefania Baraldi

J Med Chem· June 2012

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7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Pier Giovanni Baraldi, Romeo Romagnoli, Giulia Saponaro, Mojgan Aghazadeh Tabrizi, Stefania Baraldi

Bioorg Med Chem· March 2012

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Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists.
Pier Giovanni Baraldi, Stefania Baraldi, Giulia Saponaro, Delia Preti, Romeo Romagnoli

J Med Chem· January 2012

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Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists.
Pier Giovanni Baraldi, Giulia Saponaro, Mojgan Aghazadeh Tabrizi, Stefania Baraldi, Romeo Romagnoli

Bioorg Med Chem· January 2012

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New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Pier Giovanni Baraldi, Delia Preti, Abdel Naser Zaid, Giulia Saponaro, Mojgan Aghazadeh Tabrizi, Stefania Baraldi

J Med Chem· July 2011

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