Publications by authors named "Stefano Cairo"

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Mechanistic models position ceritinib as a nuclear integrity disrupting therapy in pediatric liver tumors.
Salih Demir, Thomas Kessler, Alina Hotes, Beate Häberle, Eiso Hiyama, Stefano Cairo

J Exp Clin Cancer Res· September 2025

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Identification and Credentialing of Patient Derived Xenograft Models of Invasive Lobular Breast Carcinoma using Multi-omics and Histopathology assessment.
Jagmohan Hooda, Jennifer M Atkinson, Osama Shiraz Shah, Megan Yates, Daniel D Brown, Stefano Cairo

bioRxiv· August 2025

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Relevance of transportome among the mechanisms of chemoresistance in hepatoblastoma.
Candela Cives-Losada, Maitane Asensio, Oscar Briz, Luis Miguel Chinchilla-Tábora, María Manuela Barranco, Stefano Cairo

Biochem Pharmacol· July 2025

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Functional screening identifies kinesin spindle protein inhibitor filanesib as a potential treatment option for hepatoblastoma.
Ruth Nousiainen, Katja Eloranta, Jani Saarela, Antti Hassinen, Tamara J Luck, Stefano Cairo

NPJ Precis Oncol· April 2025

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Targeting HSP90 with Ganetespib to Induce CDK1 Degradation and Promote Cell Death in Hepatoblastoma.
Lea Amelie Jung, Salih Demir, Alina Hotes, Eiso Hiyama, Tomoro Hishiki, Stefano Cairo

Cancers (Basel)· April 2025

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Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma.
Salih Demir, Alina Hotes, Tanja Schmid, Stefano Cairo, Emilie Indersie

J Exp Clin Cancer Res· November 2024

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Synergic activity of FGFR2 and MEK inhibitors in the treatment of FGFR2-amplified cancers of unknown primary.
Andrea Cavazzoni, Irene Salamon, Claudia Fumarola, Giulia Gallerani, Noemi Laprovitera, Stefano Cairo

Mol Ther· October 2024

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Modelling the impact of liver regeneration on hepatoblastoma patient-derived-xenograft tumor growth.
Marianna Cornet, Laura Brulle-Soumare, Valeria Bisio, Olivier Deas, Charlotte Mussini, Stefano Cairo

Pediatr Res· August 2024

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Computational drug prediction in hepatoblastoma by integrating pan-cancer transcriptomics with pharmacological response.
Mario Failli, Salih Demir, Álvaro Del Río-Álvarez, Juan Carrillo-Reixach, Laura Royo, Stefano Cairo

Hepatology· July 2024

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EZH2 is a key component of hepatoblastoma tumor cell growth.
Kathryn Glaser, Emily J Schepers, Harrison M Zwolshen, Charissa M Lake, Nikolai A Timchenko, Stefano Cairo

Pediatr Blood Cancer· February 2024

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Targeting G9a/DNMT1 methyltransferase activity impedes IGF2-mediated survival in hepatoblastoma.
Salih Demir, Negin Razizadeh, Emilie Indersie, Sophie Branchereau, Stefano Cairo

Hepatol Commun· February 2024

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Identification and experimental validation of druggable epigenetic targets in hepatoblastoma.
Alex Clavería-Cabello, Jose Maria Herranz, Maria Ujue Latasa, Maria Arechederra, Iker Uriarte, Stefano Cairo

J Hepatol· October 2023

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A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors.
Maria Eugénia Marques Da Costa, Sakina Zaidi, Jean-Yves Scoazec, Robin Droit, Wan Ching Lim, Stefano Cairo

Commun Biol· September 2023

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Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma.
Jie Fang, Shivendra Singh, Changde Cheng, Sivaraman Natarajan, Heather Sheppard, Stefano Cairo

Nat Commun· July 2023

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expression is elevated in hepatoblastoma and correlates with inferior patient survival.
Ruth Nousiainen, Katja Eloranta, Noora Isoaho, Stefano Cairo, David B Wilson

Front Genet· June 2023

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Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma.
Jordi Abril-Fornaguera, Laura Torrens, Carmen Andreu-Oller, Juan Carrillo-Reixach, Alex Rialdi, Stefano Cairo

Mol Cancer Ther· April 2023

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Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse.
Anthony Brown, Qingfei Pan, Li Fan, Emilie Indersie, Cheng Tian, Stefano Cairo

Commun Biol· March 2023

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CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma.
Marcus O Muench, Marina E Fomin, Alan G Gutierrez, Dolores López-Terrada, Renata Gilfanova, Stefano Cairo

Front Oncol· February 2023

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Ribonucleotide Reductase Subunit Switching in Hepatoblastoma Drug Response and Relapse.
Anthony Brown, Qingfei Pan, Li Fan, Emilie Indersie, Cheng Tian, Stefano Cairo

bioRxiv· January 2023

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SLC-0111, an inhibitor of carbonic anhydrase IX, attenuates hepatoblastoma cell viability and migration.
Katja Eloranta, Marjut Pihlajoki, Emmi Liljeström, Ruth Nousiainen, Tea Soini, Stefano Cairo

Front Oncol· January 2023

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Targeting the Unwindosome by Mebendazole Is a Vulnerability of Chemoresistant Hepatoblastoma.
Qian Li, Salih Demir, Álvaro Del Río-Álvarez, Rebecca Maxwell, Alexandra Wagner, Stefano Cairo

Cancers (Basel)· August 2022

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Targeting genome integrity dysfunctions impedes metastatic potency in non-small cell lung cancer circulating tumor cell-derived explants.
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Olivier Déas, Judith Michels, Stefano Cairo

JCI Insight· June 2022

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Vav1 Selectively Down-Regulates Akt2 through miR-29b in Certain Breast Tumors with Triple Negative Phenotype.
Silvia Grassilli, Federica Brugnoli, Stefano Cairo, Nicoletta Bianchi, Jean-Gabriel Judde

J Pers Med· June 2022

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Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification.
Benedetta Pellegrino, Andrea Herencia-Ropero, Alba Llop-Guevara, Flaminia Pedretti, Alejandro Moles-Fernández, Stefano Cairo

Cancer Res· April 2022

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Deciphering tumour tissue organization by 3D electron microscopy and machine learning.
Baudouin Denis de Senneville, Fatma Zohra Khoubai, Marc Bevilacqua, Alexandre Labedade, Kathleen Flosseau, Stefano Cairo

Commun Biol· December 2021

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