Publications by authors named "Stephan Lortz"

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Oxidative and ER stress by elevated insulin biosynthesis and palmitic acid in insulin-producing cells.
Brenda Vidrio-Huerta, Thomas Plötz, Stephan Lortz

J Mol Endocrinol· February 2024

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Luminal H O promotes ER Ca dysregulation and toxicity of palmitate in insulin-secreting INS-1E cells.
Sarah Sharifi, Maren Böger, Stephan Lortz, Ilir Mehmeti

FASEB J· January 2023

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HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells.
Vinícius M Gomes, Rosangela A M Wailemann, Gabriel S Arini, Talita C Oliveira, Daria R Q Almeida, Stephan Lortz

Cells· August 2021

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Hydrogen peroxide permeability of cellular membranes in insulin-producing cells.
Anna Laporte, Stephan Lortz, Christina Schaal, Sigurd Lenzen, Matthias Elsner

Biochim Biophys Acta Biomembr· February 2020

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Heat shock protein B1 is a key mediator of prolactin-induced beta-cell cytoprotection against oxidative stress.
Letícia F Terra, Rosangela A M Wailemann, Ancély F Dos Santos, Vinicius M Gomes, Railmara P Silva, Stephan Lortz

Free Radic Biol Med· April 2019

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ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity.
Ilir Mehmeti, Stephan Lortz, Edward Avezov, Anne Jörns, Sigurd Lenzen

Free Radic Biol Med· November 2017

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TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal HO.
Eduardo Pinho Melo, Carlos Lopes, Peter Gollwitzer, Stephan Lortz, Sigurd Lenzen

BMC Biol· March 2017

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Peroxiredoxin 4 improves insulin biosynthesis and glucose-induced insulin secretion in insulin-secreting INS-1E cells.
Ilir Mehmeti, Stephan Lortz, Matthias Elsner, Sigurd Lenzen

J Biol Chem· September 2014

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The H2O2-sensitive HyPer protein targeted to the endoplasmic reticulum as a mirror of the oxidizing thiol-disulfide milieu.
Ilir Mehmeti, Stephan Lortz, Sigurd Lenzen

Free Radic Biol Med· October 2012

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Induction of the intrinsic apoptosis pathway in insulin-secreting cells is dependent on oxidative damage of mitochondria but independent of caspase-12 activation.
Ilir Mehmeti, Ewa Gurgul-Convey, Sigurd Lenzen, Stephan Lortz

Biochim Biophys Acta· October 2011

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Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria.
Ewa Gurgul-Convey, Ilir Mehmeti, Stephan Lortz, Sigurd Lenzen

J Mol Med (Berl)· August 2011

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Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status.
Ilir Mehmeti, Sigurd Lenzen, Stephan Lortz

Mol Cell Endocrinol· January 2011

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Triiodothyronine (T3)-mediated toxicity and induction of apoptosis in insulin-producing INS-1 cells.
Helena M Ximenes, Stephan Lortz, Anne Jörns, Sigurd Lenzen

Life Sci· May 2007

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Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines.
Ewa Gurgul, Stephan Lortz, Markus Tiedge, Anne Jörns, Sigurd Lenzen

Diabetes· September 2004

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Sequential inactivation of reactive oxygen species by combined overexpression of SOD isoforms and catalase in insulin-producing cells.
Stephan Lortz, Markus Tiedge

Free Radic Biol Med· March 2003

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Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.
Anna Karenina Azevedo-Martins, Stephan Lortz, Sigurd Lenzen, Rui Curi, Decio L Eizirik

Diabetes· January 2003

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