Publications by authors named "Stephan Ort"

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Fluorogen activating protein-affibody probes: modular, no-wash measurement of epidermal growth factor receptors.
Yi Wang, Cheryl A Telmer, Brigitte F Schmidt, Josef D Franke, Stephan Ort

Bioconjug Chem· January 2015

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A designed equine herpes thymidine kinase (EHV4 TK) variant improves ganciclovir-induced cell-killing.
Theresa McSorley, Stephan Ort, Christian Monnerjahn, Manfred Konrad

Biochem Pharmacol· February 2014

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Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release.
Saugata Hazra, Andrzej Szewczak, Stephan Ort, Manfred Konrad, Arnon Lavie

Biochemistry· April 2011

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Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues .
Saugata Hazra, Stephan Ort, Manfred Konrad, Arnon Lavie

Biochemistry· August 2010

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Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase.
Saugata Hazra, Elisabetta Sabini, Stephan Ort, Manfred Konrad, Arnon Lavie

Biochemistry· February 2009

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Structural basis for substrate promiscuity of dCK.
Elisabetta Sabini, Saugata Hazra, Stephan Ort, Manfred Konrad, Arnon Lavie

J Mol Biol· May 2008

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Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues.
Theresa McSorley, Stephan Ort, Saugata Hazra, Arnon Lavie, Manfred Konrad

FEBS Lett· March 2008

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Elucidation of the active conformation of the APS-kinase domain of human PAPS synthetase 1.
Nikolina Sekulic, Kristen Dietrich, Ingo Paarmann, Stephan Ort, Manfred Konrad

J Mol Biol· March 2007

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Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization.
Michael H Godsey, Stephan Ort, Elisabetta Sabini, Manfred Konrad, Arnon Lavie

Biochemistry· January 2006

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Substrate-induced conformational changes in human UMP/CMP kinase.
Dario Segura-Peña, Nikolina Sekulic, Stephan Ort, Manfred Konrad, Arnon Lavie

J Biol Chem· August 2004

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Structure of human dCK suggests strategies to improve anticancer and antiviral therapy.
Elisabetta Sabini, Stephan Ort, Christian Monnerjahn, Manfred Konrad, Arnon Lavie

Nat Struct Biol· July 2003

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