Publications by authors named "Stephan Wullschleger"

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The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell-Mediated Killing of AML Leukemic Stem Cells.
Matteo Bianchi, Christian Reichen, Amelie Croset, Stefanie Fischer, Aline Eggenschwiler, Stephan Wullschleger

Cancer Immunol Res· July 2024

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Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8 T cells and reprogramming macrophages.
Mélanie Tichet, Stephan Wullschleger, Agnieszka Chryplewicz, Nadine Fournier, Rachel Marcone

Immunity· January 2023

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PD-1-cis IL-2R agonism yields better effectors from stem-like CD8 T cells.
Laura Codarri Deak, Valeria Nicolini, Masao Hashimoto, Maria Karagianni, Petra C Schwalie, Stephan Wullschleger

Nature· October 2022

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Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression.
Sadegh Saghafinia, Krisztian Homicsko, Annunziata Di Domenico, Stephan Wullschleger, Aurel Perren

Cancer Discov· October 2021

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Myeloid Cells Orchestrate Systemic Immunosuppression, Impairing the Efficacy of Immunotherapy against HPV Cancers.
Gabriele Galliverti, Stephan Wullschleger, Mélanie Tichet, Dhaarini Murugan, Nadine Zangger

Cancer Immunol Res· January 2020

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Nanoparticle Conjugation of Human Papillomavirus 16 E7-long Peptides Enhances Therapeutic Vaccine Efficacy against Solid Tumors in Mice.
Gabriele Galliverti, Mélanie Tichet, Sonia Domingos-Pereira, Sylvie Hauert, Denise Nardelli-Haefliger, Stephan Wullschleger

Cancer Immunol Res· November 2018

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Vagococcus teuberi sp. nov., isolated from the Malian artisanal sour milk fènè.
Stephan Wullschleger, Christoph Jans, Clelia Seifert, Sarah Baumgartner, Christophe Lacroix

Syst Appl Microbiol· March 2018

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A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics.
Anguraj Sadanandam, Stephan Wullschleger, Costas A Lyssiotis, Carsten Grötzinger, Stefano Barbi

Cancer Discov· December 2015

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A colorectal cancer classification system that associates cellular phenotype and responses to therapy.
Anguraj Sadanandam, Costas A Lyssiotis, Krisztian Homicsko, Eric A Collisson, William J Gibb, Stephan Wullschleger

Nat Med· May 2013

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Interaction of TAPP adapter proteins with phosphatidylinositol (3,4)-bisphosphate regulates B-cell activation and autoantibody production.
Ivan Landego, Nipun Jayachandran, Stephan Wullschleger, Ting-ting Zhang, Ian W Gibson

Eur J Immunol· October 2012

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Quantitative MRI establishes the efficacy of PI3K inhibitor (GDC-0941) multi-treatments in PTEN-deficient mice lymphoma.
Stephan Wullschleger, Juan M García-Martínez, Suzanne L Duce

Anticancer Res· February 2012

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Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney.
Laura R Pearce, Eeva M Sommer, Kei Sakamoto, Stephan Wullschleger, Dario R Alessi

Biochem J· May 2011

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Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis.
Stephan Wullschleger, David H Wasserman, Alex Gray, Kei Sakamoto, Dario R Alessi

Biochem J· March 2011

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How moderate changes in Akt T-loop phosphorylation impact on tumorigenesis and insulin resistance.
Stephan Wullschleger, Kei Sakamoto, Lana Johnstone, Suzanne Duce, Stewart Fleming

Dis Model Mech· January 2011

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Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
Xu Huang, Stephan Wullschleger, Natalia Shpiro, Victoria A McGuire, Kei Sakamoto

Biochem J· June 2008

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Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Jose R Bayascas, Stephan Wullschleger, Kei Sakamoto, Juan M García-Martínez, Carol Clacher

Mol Cell Biol· May 2008

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Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
Laura R Pearce, Xu Huang, Jérôme Boudeau, Rafał Pawłowski, Stephan Wullschleger

Biochem J· August 2007

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Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation.
Olga Göransson, Maria Deak, Stephan Wullschleger, Nick A Morrice, Alan R Prescott

J Cell Sci· October 2006

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TOR signaling in growth and metabolism.
Stephan Wullschleger, Robbie Loewith, Michael N Hall

Cell· February 2006

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Molecular organization of target of rapamycin complex 2.
Stephan Wullschleger, Robbie Loewith, Wolfgang Oppliger, Michael N Hall

J Biol Chem· September 2005

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Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.
Yoshiaki Kamada, Yuko Fujioka, Nobuo N Suzuki, Fuyuhiko Inagaki, Stephan Wullschleger

Mol Cell Biol· August 2005

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Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.
Robbie Loewith, Estela Jacinto, Stephan Wullschleger, Anja Lorberg, José L Crespo

Mol Cell· September 2002

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