Publications by authors named "Stephane B Richard"

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Machine learning model to predict oncologic outcomes for drugs in randomized clinical trials.
Alexander V Schperberg, Amélie Boichard, Igor F Tsigelny, Stéphane B Richard, Razelle Kurzrock

Int J Cancer· November 2020

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The Crossroads of Precision Medicine and Therapeutic Decision-Making: Use of an Analytical Computational Platform to Predict Response to Cancer Treatments.
Amélie Boichard, Stephane B Richard, Razelle Kurzrock

Cancers (Basel)· January 2020

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Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ.
Chyuan-Chuan Wu, Thomas J Baiga, Michael Downes, James J La Clair, Annette R Atkins, Stephane B Richard

Proc Natl Acad Sci U S A· March 2017

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Identify drug repurposing candidates by mining the protein data bank.
Fabrice Moriaud, Stéphane B Richard, Stewart A Adcock, Laetitia Chanas-Martin, Jean-Sébastien Surgand

Brief Bioinform· July 2011

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Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities.
Takuto Kumano, Stéphane B Richard, Joseph P Noel, Makoto Nishiyama, Tomohisa Kuzuyama

Bioorg Med Chem· September 2008

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A soluble, magnesium-independent prenyltransferase catalyzes reverse and regular C-prenylations and O-prenylations of aromatic substrates.
Yvonne Haagen, Inge Unsöld, Lucia Westrich, Bertolt Gust, Stéphane B Richard

FEBS Lett· June 2007

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Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses.
Chang-Jun Liu, Bettina E Deavours, Stéphane B Richard, Jean-Luc Ferrer, Jack W Blount, Richard A Dixon

Plant Cell· December 2006

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Structural basis for the design of potent and species-specific inhibitors of 3-hydroxy-3-methylglutaryl CoA synthases.
Florence Pojer, Jean-Luc Ferrer, Stéphane B Richard, Dinesh A Nagegowda, Mee-Len Chye

Proc Natl Acad Sci U S A· August 2006

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Absence of substrate channeling between active sites in the Agrobacterium tumefaciens IspDF and IspE enzymes of the methyl erythritol phosphate pathway.
Christian Lherbet, Florence Pojer, Stéphane B Richard, Joseph P Noel, C D Poulter

Biochemistry· March 2006

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Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.
Tomohisa Kuzuyama, Joseph P Noel, Stéphane B Richard

Nature· June 2005

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Kinetic analysis of Escherichia coli 2-C-methyl-D-erythritol-4-phosphate cytidyltransferase, wild type and mutants, reveals roles of active site amino acids.
Stéphane B Richard, Antonietta M Lillo, Charles N Tetzlaff, Marianne E Bowman, Joseph P Noel

Biochemistry· September 2004

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The Oligomeric states of Haloarcula marismortui malate dehydrogenase are modulated by solvent components as shown by crystallographic and biochemical studies.
Adriana Irimia, Christine Ebel, Dominique Madern, Stéphane B Richard, Lawrence W Cosenza

J Mol Biol· February 2003

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Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway.
Stéphane B Richard, Jean-Luc Ferrer, Marianne E Bowman, Antonietta M Lillo, Charles N Tetzlaff

J Biol Chem· March 2002

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