Publications by authors named "Stephanie Letast"

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Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer.
Emmanuel Douez, Emilie Allard-Vannier, Imène Ait Mohamed Amar, Louis Jolivet, Fanny Boursin, Stéphanie Letast

J Control Release· February 2024

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Intra-Domain Cysteines (IDC), a New Strategy for the Development of Original Antibody Fragment-Drug Conjugates (FDCs).
Louis Jolivet, Imène Ait Mohamed Amar, Catherine Horiot, Fanny Boursin, Cyril Colas, Stéphanie Letast

Pharmaceutics· July 2022

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Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate.
Imene Ait Mohamed Amar, Steve Huvelle, Emmanuel Douez, Stéphanie Letast, Sylvain Henrion

Eur J Med Chem· February 2022

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Internalization of Foldamer-Based DNA Mimics through a Site-Specific Antibody Conjugate to Target HER2-Positive Cancer Cells.
Valentina Corvaglia, Imène Ait Mohamed Amar, Véronique Garambois, Stéphanie Letast, Aurélie Garcin

Pharmaceuticals (Basel)· June 2021

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Site-Specific Conjugation of Auristatins onto Engineered scFv Using Second Generation Maleimide to Target HER2-positive Breast Cancer in Vitro.
Nicolas Aubrey, Emilie Allard-Vannier, Camille Martin, Francesca Bryden, Stéphanie Letast

Bioconjug Chem· November 2018

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Impact of cathepsin B-sensitive triggers and hydrophilic linkers on in vitro efficacy of novel site-specific antibody-drug conjugates.
Francesca Bryden, Camille Martin, Stéphanie Letast, Eva Lles, Inmaculada Viéitez-Villemin

Org Biomol Chem· March 2018

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Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).
Brice Korkmaz, Adam Lesner, Stephanie Letast, Yassir K Mahdi, Marie-Lise Jourdan

Semin Immunopathol· July 2013

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