Publications by authors named "Stephanie Ruez"

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Insights from a novel in vitro cigarette smoke induction model: comparison of 24 primary human hepatocyte donors of diverse demographics and multiple sources.
Ann-Kathrin Lenich, Stephanie Ruez

Arch Toxicol· December 2025

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Evaluating CYP enzyme induction by cigarette smoking: a new in vitro approach using primary human hepatocytes.
Ann-Kathrin Lenich, Stephanie Ruez

Arch Toxicol· November 2025

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Assessing granisetron as a specific CYP1A1 substrate in primary human hepatocytes: A comprehensive evaluation for drug development studies.
Ann-Kathrin Lenich, Julie Nilles, Vanessa Scherer, Fangjie Li, Stephanie Ruez

Drug Metab Dispos· March 2025

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Lack of CYP3A4 protein induction despite mRNA induction in primary hepatocytes exposed to rifabutin as a possible explanation for its low interaction risk in vivo.
Julie Nilles, Dirk Theile, Johanna Weiss, Walter E Haefeli, Stephanie Ruez

Arch Toxicol· August 2024

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The differences in drug disposition gene induction by rifampicin and rifabutin are unlikely due to different effects on important pregnane X receptor (NR1I2) splice variants.
Julie Nilles, Johanna Weiss, Martin Masin, Christopher Tuffs, Moritz J Strowitzki, Stephanie Ruez

Naunyn Schmiedebergs Arch Pharmacol· April 2024

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Comprehensive in vitro analysis evaluating the variable drug-drug interaction risk of rifampicin compared to rifabutin.
Julie Nilles, Johanna Weiss, Max Sauter, Walter E Haefeli, Stephanie Ruez

Arch Toxicol· August 2023

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How to avoid misinterpretation of dual reporter gene assay data affected by cell damage.
Julie Nilles, Johanna Weiss, Walter E Haefeli, Stephanie Ruez, Dirk Theile

Arch Toxicol· September 2022

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Serum Amyloid A1 Induces Classically Activated Macrophages: A Role for Enhanced Fibril Formation.
Ann-Kathrin Gaiser, Shanna Bauer, Stephanie Ruez, Karlheinz Holzmann, Marcus Fändrich

Front Immunol· November 2021

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Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research.
Tomoki Yamashita, Tatsuya Inui, Jumpei Yokota, Kentaro Kawakami, Gaku Morinaga, Stephanie Ruez

Mol Ther Methods Clin Dev· September 2021

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