Publications by authors named "Stephen B Gruber"

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Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis.
Emma Hazelwood, Lucy J Goudswaard, Matthew A Lee, Marina Vabistsevits, Dimitri J Pournaras, Stephen B Gruber

J Natl Cancer Inst· December 2025

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Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention.
Qing Li, Qingyuan Song, Zhishan Chen, Jungyoon Choi, Victor Moreno, Stephen B Gruber

Am J Hum Genet· December 2025

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Variant-Specific Mendelian Risk Prediction Model.
Julie-Alexia Dias, Eunchan Bae, Theodore Huang, Jinbo Chen, Stephen B Gruber

Stat Med· December 2025

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Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes.
Tabitha A Harrison, Syed H Zaidi, Hang Yin, Robert S Steinfelder, Conghui Qu, Stephen B Gruber

BMC Cancer· December 2025

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Physical activity and molecular subtypes of colorectal cancer: a pooled observational analysis and Mendelian randomization study.
Christos V Chalitsios, Georgios Markozannes, Elom K Aglago, Sonja I Berndt, Daniel D Buchanan, Stephen B Gruber

JNCI Cancer Spectr· November 2025

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Using gene-environment interactions to explore pathways for colorectal cancer risk.
Emmanouil Bouras, Ren Yu, Andre E Kim, Georgios Markozannes, Neil Murphy, Stephen B Gruber

EBioMedicine· November 2025

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Efficient deep neural networks for cancer detection on histopathology combining attention and image downsampling.
Miguel Socolovsky, Alberto López, Joel K Greenson, Gad Rennert, Stephen B Gruber

Sci Rep· October 2025

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Genetic risk factors modulate the association between physical activity and colorectal cancer.
Anita R Peoples, Mireia Obón-Santacana, Andre E Kim, Eric S Kawaguchi, Yubo Fu, Stephen B Gruber

Res Sq· September 2025

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Prevalence of BRCA1 and BRCA2 Variants in an Unselected Population of Women With Breast Cancer.
Joanne E Mortimer, Sidney S Lindsey, Elyssa Zukin, Wai Park, Duveen Sturgeon, Stephen B Gruber

JAMA Netw Open· September 2025

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Pathway polygenic risk scores (pPRS) for the analysis of gene-environment interaction.
W James Gauderman, Yubo Fu, Bryan Queme, Eric Kawaguchi, Yinqiao Wang, Stephen B Gruber

PLoS Genet· August 2025

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Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women.
Jovia L Nierenberg, Aaron W Adamson, Donglei Hu, Scott Huntsman, Carmina Patrick, Stephen B Gruber

Nat Commun· August 2025

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Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention.
Qing Li, Qingyuan Song, Zhishan Chen, Jungyoon Choi, Victor Moreno, Stephen B Gruber

medRxiv· July 2025

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Identification of Genetic Variations in HLA Region for Kidney Functions.
Wan-Hsuan Chou, Chun-Yu Wei, Min-Rou Lin, Che-Mai Chang, Stephen B Gruber

HLA· June 2025

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Red meat intake interacts with a TGF-β-pathway-based polygenic risk score to impact colorectal cancer risk: Application of a novel approach for polygenic risk score construction.
Joel Sanchez Mendez, Bryan Queme, Yubo Fu, John Morrison, Juan P Lewinger, Stephen B Gruber

medRxiv· June 2025

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Association of Genetic Liability to Allergic Diseases with Overall and Early-Onset Colorectal Cancer Risk: A Mendelian Randomization Study.
Saleh Alduhayh, Ruhina Shirin Laskar, Xia Jiang, Zhaozhong Zhu, Emma E Vincent, Stephen B Gruber

Cancer Epidemiol Biomarkers Prev· May 2025

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Multi-tissue expression and splicing data prioritise anatomical subsite- and sex-specific colorectal cancer susceptibility genes.
Emma Hazelwood, Daffodil M Canson, Benedita Deslandes, Xuemin Wang, Pik Fang Kho, Stephen B Gruber

Nat Commun· May 2025

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Waist Circumference, a Body Shape Index, and Molecular Subtypes of Colorectal Cancer: A Pooled Analysis of Four Cohort Studies.
Christos V Chalitsios, Georgios Markozannes, Christos Papagiannopoulos, Elom K Aglago, Sonja I Berndt, Stephen B Gruber

Cancer Epidemiol Biomarkers Prev· April 2025

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Ataxia telangiectasia-mutated rs56009889 and risk of common cancers.
Ofra Barnet-Griness, Stephen B Gruber, Steven M Lipkin, Katerina Shulman, Riad Haddad

Eur J Cancer Prev· March 2025

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Characterization of Additive Gene-environment Interactions For Colorectal Cancer Risk.
Claire E Thomas, Yi Lin, Michelle Kim, Eric S Kawaguchi, Conghui Qu, Stephen B Gruber

Epidemiology· January 2025

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Associations of blood lipids and LDL cholesterol lowering drug-targets with colorectal cancer risk: a Mendelian randomisation study.
Wing Ching Chan, Lili Liu, Emmanouil Bouras, Verena Zuber, Wanqing Wen, Stephen B Gruber

Br J Cancer· January 2025

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Breast Cancer MRI Screening of Patients After Multiplex Gene Panel Testing.
Leah A Naghi, Julie O Culver, Charité Ricker, Duveen Sturgeon, Kerry Kingham, Stephen B Gruber

JAMA Netw Open· January 2025

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Pathway Polygenic Risk Scores (pPRS) for the Analysis of Gene-environment Interaction.
W James Gauderman, Yubo Fu, Bryan Queme, Eric Kawaguchi, Yinqiao Wang, Stephen B Gruber

bioRxiv· December 2024

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Differences in tumor-associated T-cell receptor repertoires between early-onset and average-onset colorectal cancer.
Ya-Yu Tsai, Kanika G Nair, Shimoli V Barot, Shao Xiang, Suneel Kamath, Stephen B Gruber

J Natl Cancer Inst· October 2024

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Folate intake and colorectal cancer risk according to genetic subtypes defined by targeted tumor sequencing.
Elom K Aglago, Conghui Qu, Sophia Harlid, Amanda I Phipps, Robert S Steinfelder, Stephen B Gruber

Am J Clin Nutr· September 2024

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Genetic Variation and Regulation of MICA Alters Natural Killer Cell-Mediated Immunosurveillance in Early-Onset Colorectal Cancer.
Heather M McGee, Joseph D Bonner, Colt Egelston, Yubo Fu, Oscar Colunga Flores, Stephen B Gruber

medRxiv· September 2024

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