Publications by authors named "Stephen Byrn"

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Drug Property Optimization: Design, Synthesis, and Characterization of Novel Pharmaceutical Salts and Cocrystal-Salt of Lumefantrine.
Bolaji C Dayo Owoyemi, Matthias Zeller, Brenda Pereira da Silva, Amos O Akinyemi, Romulo A Ando, Stephen R Byrn

Mol Pharm· February 2025

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Modeling the Structure of Ketoprofen-Poly(vinylpyrrolidone) Amorphous Solid Dispersions with Empirical Potential Structure Refinements of X-ray Scattering Data.
Stephen K Wilke, Abdulrahman Al-Rubkhi, Chris J Benmore, Stephen R Byrn, Richard Weber

Mol Pharm· August 2024

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Accelerated Development of Pharmaceuticals Past, Present, and Future.
Stephen R Byrn

Pharm Res· August 2024

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A Quality by Design Approach for Optimizing Solid Lipid Nanoparticles of Bedaquiline for Improved Product Performance.
Mercy A Okezue, Chidi Uche, Adekoya Adebola, Stephen R Byrn

AAPS PharmSciTech· July 2024

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Molecular structure of ketoprofen-polyvinylpyrrolidone solid dispersions prepared by different amorphization methods.
Stephen K Wilke, Chris J Benmore, Vrishank Menon, Dan Smith, Stephen R Byrn

RSC Pharm· April 2024

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Potency and Powder X-ray Diffraction (PXRD) Evaluation of Levothyroxine Sodium Tablets under Ambient, Accelerated, and Stressed Conditions.
Mercy A Okezue, Stephen R Byrn, Josiah Probost, Madison Lucas, Kari L Clase

Pharmaceuticals (Basel)· December 2023

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Probing Molecular Packing of Amorphous Pharmaceutical Solids Using X-ray Atomic Pair Distribution Function and Solid-State NMR.
Zhenxuan Chen, Haichen Nie, Chris J Benmore, Pamela A Smith, Yong Du, Stephen Byrn

Mol Pharm· November 2023

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Synthesis, Characterization, and Stability Assessment for the Benzoate, Hydrochloride, Malonate, and Nicotinate Salts of Bedaquiline.
Mercy A Okezue, Stephen R Byrn

Pharmaceuticals (Basel)· February 2023

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The Structure of Liquid and Glassy Carbamazepine.
Chris J Benmore, Angela Edwards, Oliver L G Alderman, Brian R Cherry, Pamela Smith, Stephen Byrn

Quantum Beam Sci· December 2022

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Determining the solubilities for benzoate, nicotinate, hydrochloride, and malonate salts of bedaquiline.
Mercy A Okezue, Stephen J Byrn, Kari L Clase

Int J Pharm· November 2022

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Hot-melt extrudability of amorphous solid dispersions of flubendazole-copovidone: An exploratory study of the effect of drug loading and the balance of adjuvants on extrudability and dissolution.
João M C de Assis, Eduardo J Barbosa, Vinícius D N Bezzon, Felipe R Lourenço, Flavio M S Carvalho, Stephen R Byrn

Int J Pharm· February 2022

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The Identification of Quality Risk Factors for Non-biological Complex Drugs and Epilepsy Drugs Using Statistical Analysis of Formulation-Based Recalls in the USA.
Emily A Kerstiens, Stephen R Byrn, Kari L Clase

AAPS PharmSciTech· December 2021

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Salts and Polymorph Screens for Bedaquiline.
Mercy Okezue, Susan Bogdanowich-Knipp, Daniel Smith, Matthias Zeller, Stephen Byrn

AAPS PharmSciTech· August 2021

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Evaluation of tableting performance of Poly (ethylene oxide) in abuse-deterrent formulations using compaction simulation studies.
Dongyue Yu, Raghunadha Reddy Seelam, Feng Zhang, Stephen R Byrn, Stephen W Hoag

J Pharm Sci· July 2021

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Acoustic levitation and high-resolution synchrotron X-ray powder diffraction: A fast screening approach of niclosamide amorphous solid dispersions.
Eduardo J Barbosa, Marco A B Andrade, Mariana R Gubitoso, Vinícius D N Bezzon, Pamela A Smith, Stephen R Byrn

Int J Pharm· June 2021

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Amorphous dispersions of flubendazole in hydroxypropyl methylcellulose: Formulation stability assisted by pair distribution function analysis.
Vinicius D N Bezzon, Fabio F Ferreira, Pamela Smith, Chris J Benmore, Stephen R Byrn

Int J Pharm· May 2021

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Maleate salts of bedaquiline.
Matthias Zeller, Susan Bogdanowich-Knipp, Pamela Smith, Dale K Purcell, Mercy Okezue, Stephen R Byrn

Acta Crystallogr E Crystallogr Commun· April 2021

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Development of a Pediatric Mini-Tablet Formulation for Expedited Preclinical Studies.
Monika Lavan, Xueqi Wang, Robyn McCain, Amber Jannasch, Bruce Cooper, Stephen Byrn

AAPS PharmSciTech· January 2021

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Crystal structures of salts of bedaquiline.
Mercy Okezue, Daniel Smith, Matthias Zeller, Stephen R Byrn, Pamela Smith

Acta Crystallogr C Struct Chem· November 2020

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Atomic-Level Drug Substance and Polymer Interaction in Posaconazole Amorphous Solid Dispersion from Solid-State NMR.
Xingyu Lu, Mingyue Li, Chengbin Huang, Michael B Lowinger, Wei Xu, Stephen R Byrn

Mol Pharm· July 2020

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An Analytic Investigation of the Drug Formulation-Based Recalls in the USA: See More Beyond the Literal.
Mian Yang, Stephen R Byrn, Kari L Clase

AAPS PharmSciTech· July 2020

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Molecular Mechanism of Crystalline-to-Amorphous Conversion of Pharmaceutical Solids from F Magic Angle Spinning NMR.
Xingyu Lu, Chengbin Huang, Mingyue Li, Daniel Skomski, Wei Xu, Stephen R Byrn

J Phys Chem B· June 2020

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Molecular packing of pharmaceuticals analyzed with paramagnetic relaxation enhancement and ultrafast magic angle pinning NMR.
Xingyu Lu, Yu Tsutsumi, Chengbin Huang, Wei Xu, Stephen R Byrn

Phys Chem Chem Phys· June 2020

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Physical Barrier Type Abuse-Deterrent Formulations: Mechanistic Understanding of Sintering-Induced Microstructural Changes in Polyethylene Oxide Placebo Tablets.
Heather J Boyce, Vivek S Dave, Myke Scoggins, Vadim J Gurvich, Daniel T Smith, Stephen R Byrn

AAPS PharmSciTech· January 2020

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Predictive and Accelerated Formulation Design Using Synchrotron Methods.
Stephen R Byrn, Xiaoming Sean Chen, Pamela A Smith

AAPS PharmSciTech· April 2019

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