Publications by authors named "Stephen Carl"

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Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity.
Sayumi Yamazoe, Yam Poudel, Emanuela Sega, Anandaroop Mukhopadhyay, Radha Ramakrishnan, Stephen Carl

J Med Chem· June 2025

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Target-Mediated Drug Disposition Affects the Pharmacokinetics of Interleukin-10 Fragment Crystallizable Fusion Proteins at Pharmacologically Active Doses.
Zheng Yang, Surendran Rajendran, Vanessa Spires, Brian Poirson, Murali Gururajan, Stephen Carl

Drug Metab Dispos· July 2022

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Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.
Zheng Yang, James Loy, Brian Poirson, Yanshan Dai, Surendran Rajendran, Stephen Carl

Front Pharmacol· June 2022

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Bead-extraction and heat-dissociation (BEHD): A novel way to overcome drug and matrix interference in immunogenicity testing.
Weifeng Xu, Michael Sank, Jennifer Cummings, Stephen Carl, Marina Juhel

J Immunol Methods· November 2018

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AggScore: Prediction of aggregation-prone regions in proteins based on the distribution of surface patches.
Kannan Sankar, Stanley R Krystek, Stephen M Carl, Tyler Day, Johannes K X Maier

Proteins· November 2018

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The effects of intralaboratory modifications to media composition and cell source on the expression of pharmaceutically relevant transporters and metabolizing genes in the Caco-2 cell line.
Wyatt J Roth, David J Lindley, Stephen M Carl, Gregory T Knipp

J Pharm Sci· October 2012

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The effects of media on pharmaceutically relevant transporters in the human HT-29 adenocarcinoma cell line: does culture media need to be controlled?
David J Lindley, Wyatt J Roth, Stephen M Carl, Gregory T Knipp

J Pharm Sci· April 2012

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THE EVALUATION OF PEPTIDE/HISTIDINE TRANSPORTER 1 (PHT1) FUNCTION: UPTAKE KINETICS UTILIZING A COS-7 STABLY TRANSFECTED CELL LINE.
David J Lindley, Stephen M Carl, Stephanie A Mowery, Gregory T Knipp

Rev Mex Cienc Farm· October 2011

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ABC and SLC transporter expression and proton oligopeptide transporter (POT) mediated permeation across the human blood--brain barrier cell line, hCMEC/D3 [corrected].
Stephen M Carl, David J Lindley, Debanjan Das, Pierre O Couraud, Babette B Weksler

Mol Pharm· August 2010

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The effects of excipients on transporter mediated absorption.
Jonathan Goole, David J Lindley, Wyatt Roth, Stephen M Carl, Karim Amighi

Int J Pharm· June 2010

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The pharmacodynamic effects of sirolimus and sirolimus-calcineurin inhibitor combinations on macrophage scavenger and nuclear hormone receptors.
A Scott Mathis, Song Jin, Gary S Friedman, Felice Peng, Stephen M Carl

J Pharm Sci· January 2007

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