Publications by authors named "Stephen Langer"

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Activation of FoxO1 prevents and reverses cardiac hypertrophy from diverse stimuli.
Thomas G Martin, Stephen J Langer, Claudia Crocini, Eunhee Chung, Leslie A Leinwand

J Mol Cell Cardiol· August 2025

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Regression of postprandial cardiac hypertrophy in burmese pythons is mediated by FoxO1.
Thomas G Martin, Dakota R Hunt, Stephen J Langer, Yuxiao Tan, Christopher C Ebmeier

Proc Natl Acad Sci U S A· October 2024

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A Conserved Mechanism of Cardiac Hypertrophy Regression through FoxO1.
Thomas G Martin, Dakota R Hunt, Stephen J Langer, Yuxiao Tan, Christopher C Ebmeier

bioRxiv· January 2024

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Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies.
Sarah J Lehman, Artur Meller, Shahlo O Solieva, Jeffrey M Lotthammer, Lina Greenberg, Stephen J Langer

bioRxiv· July 2023

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Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States.
Sampath K Gollapudi, Weikang Ma, Srinivas Chakravarthy, Ariana C Combs, Na Sa, Stephen Langer

J Mol Biol· November 2021

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Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties.
Carlos D Vera, Chloe A Johnson, Jonathan Walklate, Arjun Adhikari, Marina Svicevic, Stephen J Langer

J Biol Chem· November 2019

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Spatial strain correlations, machine learning, and deformation history in crystal plasticity.
Stefanos Papanikolaou, Michail Tzimas, Andrew C E Reid, Stephen A Langer

Phys Rev E· May 2019

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Pinus ponderosa: A checkered past obscured four species.
Ann Willyard, David S Gernandt, Kevin Potter, Valerie Hipkins, Paula Marquardt, Stephen K Langer

Am J Bot· January 2017

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Morphology Dependent Flow Stress in Nickel-Based Superalloys in the Multi-Scale Crystal Plasticity Framework.
Shahriyar Keshavarz, Zara Molaeinia, Andrew C E Reid, Stephen A Langer

Crystals (Basel)· January 2017

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Estrogen receptor profiling and activity in cardiac myocytes.
Emily K Pugach, Christa L Blenck, Joseph M Dragavon, Stephen J Langer, Leslie A Leinwand

Mol Cell Endocrinol· August 2016

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A NON-SCHMID CRYSTAL PLASTICITY FINITE ELEMENT APPROACH TO MULTI-SCALE MODELING OF NICKEL-BASED SUPERALLOYS.
Shahriyar Keshavarz, Somnath Ghosh, Andrew C E Reid, Stephen A Langer

Acta Mater· August 2016

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Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function.
Suman Nag, Ruth F Sommese, Zoltan Ujfalusi, Ariana Combs, Stephen Langer

Sci Adv· October 2015

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The python project: a unique model for extending research opportunities to undergraduate students.
Pamela A Harvey, Christopher Wall, Stephen W Luckey, Stephen Langer, Leslie A Leinwand

CBE Life Sci Educ· August 2015

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The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin.
Marieke Bloemink, John Deacon, Stephen Langer, Carlos Vera, Ariana Combs

J Biol Chem· February 2014

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Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway.
Huan Wang, Mark W Tibbitt, Stephen J Langer, Leslie A Leinwand, Kristi S Anseth

Proc Natl Acad Sci U S A· November 2013

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A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme.
Yukihito Kabuyama, Elizabeth S Litman, Paul D Templeton, Sandra I Metzner, Eric S Witze, Stephen J Langer

Mol Cell Proteomics· October 2009

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Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression.
Travis S Hughes, Stephen J Langer, Salla I Virtanen, Raymond A Chavez, Linda R Watkins

J Gene Med· September 2009

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Intrathecal injection of naked plasmid DNA provides long-term expression of secreted proteins.
Travis S Hughes, Stephen J Langer, Kirk W Johnson, Raymond A Chavez, Linda R Watkins

Mol Ther· January 2009

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A randomized library approach to identifying functional lox site domains for the Cre recombinase.
Jamie Sheren, Stephen J Langer, Leslie A Leinwand

Nucleic Acids Res· September 2007

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Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats.
Annemarie Ledeboer, Brian M Jekich, Evan M Sloane, John H Mahoney, Stephen J Langer

Brain Behav Immun· July 2007

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Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain.
Erin D Milligan, Evan M Sloane, Stephen J Langer, Travis S Hughes, Brian M Jekich

Pain· December 2006

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Shuttling of HDAC5 in H9C2 cells regulates YY1 function through CaMKIV/PKD and PP2A.
Carmen C Sucharov, Stephen Langer, Michael Bristow, Leslie Leinwand

Am J Physiol Cell Physiol· November 2006

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Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain.
Erin D Milligan, Ryan G Soderquist, Stephanie M Malone, John H Mahoney, Travis S Hughes, Stephen J Langer

Neuron Glia Biol· November 2006

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Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling.
Yukihito Kabuyama, Stephen J Langer, Kirsi Polvinen, Yoshimi Homma, Katheryn A Resing

Mol Cell Proteomics· August 2006

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Velocity fluctuations in a steadily sheared model foam.
Ian K Ono, Shubha Tewari, Stephen A Langer, Andrea J Liu

Phys Rev E Stat Nonlin Soft Matter Phys· June 2003

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