Publications by authors named "Stephen Loukin"

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A competing hydrophobic tug on L596 to the membrane core unlatches S4-S5 linker elbow from TRP helix and allows TRPV4 channel to open.
Jinfeng Teng, Stephen H Loukin, Andriy Anishkin, Ching Kung

Proc Natl Acad Sci U S A· October 2016

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A channelopathy mechanism revealed by direct calmodulin activation of TrpV4.
Stephen H Loukin, Jinfeng Teng, Ching Kung

Proc Natl Acad Sci U S A· July 2015

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L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel.
Jinfeng Teng, Stephen H Loukin, Andriy Anishkin, Ching Kung

Proc Natl Acad Sci U S A· March 2015

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The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements.
Jinfeng Teng, Stephen Loukin, Andriy Anishkin, Ching Kung

Pflugers Arch· January 2015

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Feeling the hidden mechanical forces in lipid bilayer is an original sense.
Andriy Anishkin, Stephen H Loukin, Jinfeng Teng, Ching Kung

Proc Natl Acad Sci U S A· June 2014

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Yeast luminometric and Xenopus oocyte electrophysiological examinations of the molecular mechanosensitivity of TRPV4.
Jinfeng Teng, Stephen Loukin, Xinliang Zhou, Ching Kung

J Vis Exp· December 2013

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Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutations.
Stephen Loukin, Zhenwei Su, Ching Kung

PLoS One· May 2011

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Wild-type and brachyolmia-causing mutant TRPV4 channels respond directly to stretch force.
Stephen Loukin, Xinliang Zhou, Zhenwei Su, Yoshiro Saimi, Ching Kung

J Biol Chem· August 2010

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Forward genetic analysis reveals multiple gating mechanisms of TRPV4.
Stephen Loukin, Zhenwei Su, Xinliang Zhou, Ching Kung

J Biol Chem· June 2010

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The use of yeast to understand TRP-channel mechanosensitivity.
Zhenwei Su, Xinliang Zhou, Stephen H Loukin, W John Haynes, Yoshiro Saimi

Pflugers Arch· September 2009

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Hypotonic shocks activate rat TRPV4 in yeast in the absence of polyunsaturated fatty acids.
Stephen H Loukin, Zhenwei Su, Ching Kung

FEBS Lett· February 2009

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Mechanical force and cytoplasmic Ca(2+) activate yeast TRPY1 in parallel.
Zhenwei Su, Xinliang Zhou, Stephen H Loukin, Yoshiro Saimi, Ching Kung

J Membr Biol· February 2009

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A genome-wide survey suggests an osmoprotective role for vacuolar Ca2+ release in cell wall-compromised yeast.
Stephen Loukin, Xinliang Zhou, Ching Kung, Yoshiro Saimi

FASEB J· July 2008

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Indole and other aromatic compounds activate the yeast TRPY1 channel.
W John Haynes, Xin-Liang Zhou, Zhen-Wei Su, Stephen H Loukin, Yoshiro Saimi

FEBS Lett· April 2008

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Yeast gain-of-function mutations reveal structure-function relationships conserved among different subfamilies of transient receptor potential channels.
Zhenwei Su, Xinliang Zhou, W John Haynes, Stephen H Loukin, Andriy Anishkin

Proc Natl Acad Sci U S A· December 2007

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Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate.
Xinliang Zhou, Zhenwei Su, Andriy Anishkin, W John Haynes, Eric M Friske, Stephen H Loukin

Proc Natl Acad Sci U S A· September 2007

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Lipid perturbations sensitize osmotic down-shock activated Ca2+ influx, a yeast "deletome" analysis.
Stephen H Loukin, Ching Kung, Yoshiro Saimi

FASEB J· June 2007

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Prokaryotic K(+) channels: from crystal structures to diversity.
Mario M-C Kuo, W John Haynes, Stephen H Loukin, Ching Kung, Yoshiro Saimi

FEMS Microbiol Rev· November 2005

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Microbial K+ channels.
Stephen H Loukin, Mario M-C Kuo, Xin-Liang Zhou, W John Haynes, Ching Kung

J Gen Physiol· June 2005

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The transient receptor potential channel on the yeast vacuole is mechanosensitive.
Xin-Liang Zhou, Ann F Batiza, Stephen H Loukin, Chris P Palmer, Ching Kung

Proc Natl Acad Sci U S A· June 2003

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Carboxyl tail prevents yeast K(+) channel closure: proposal of an integrated model of TOK1 gating.
Stephen H Loukin, Yoshiro Saimi

Biophys J· February 2002

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The carboxyl tail forms a discrete functional domain that blocks closure of the yeast K+ channel.
Stephen H Loukin, Junyu Lin, Umair Athar, Christopher Palmer, Yoshiro Saimi

Proc Natl Acad Sci U S A· February 2002

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