Publications by authors named "Stephen P Higgins"

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SERPINE1 drives molecular synergies in colorectal cancer.
Naziba Nuha, Stephen P Higgins, Ralf-Peter Czekay, Craig E Higgins, Lynn Guo, Paul J Higgins

Am J Physiol Cell Physiol· January 2026

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SERPINE1: Role in Cholangiocarcinoma Progression and a Therapeutic Target in the Desmoplastic Microenvironment.
Ralf-Peter Czekay, Craig E Higgins, Hasan Basri Aydin, Rohan Samarakoon, Nusret Bekir Subasi, Stephen P Higgins, Paul J Higgins

Cells· May 2024

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The dark art of syphilis serology - an analysis of testing algorithms at a UK reference laboratory.
Antonia Scobie, Colin S Brown, Patrick French, Matthew Donati, Peter Muir, Stephen P Higgins

J Med Microbiol· April 2022

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The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney.
Craig E Higgins, Jiaqi Tang, Stephen P Higgins, Cody C Gifford, Badar M Mian, Paul J Higgins

Front Cell Dev Biol· July 2021

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TGF-β1-p53 cooperativity regulates a profibrotic genomic program in the kidney: molecular mechanisms and clinical implications.
Craig E Higgins, Jiaqi Tang, Badar M Mian, Stephen P Higgins, Cody C Gifford, Paul J Higgins

FASEB J· October 2019

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The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1.
Rohan Samarakoon, Stephen P Higgins, Craig E Higgins, Paul J Higgins

Biomolecules· August 2019

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Screening for asymptomatic neurosyphilis in HIV patients after treatment of early syphilis: an observational study.
Andrew Tomkins, Shazaad Ahmad, Darren E Cousins, Caroline M Thng, Francisco Javier Vilar, Stephen P Higgins

Sex Transm Infect· August 2018

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TGF-β1/p53 signaling in renal fibrogenesis.
Stephen P Higgins, Yi Tang, Craig E Higgins, Badar Mian, Wenzheng Zhang, Paul J Higgins

Cell Signal· March 2018

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Syphilitic jaundice: a rare manifestation of the secondary stage presenting a missed opportunity to prevent ocular syphilis.
Joanne Curran, Stephen Peter Higgins

BMJ Case Rep· January 2018

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Yaws.
Michael Marks, Dornubari Lebari, Anthony W Solomon, Stephen P Higgins

Int J STD AIDS· September 2015

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Primary herpes simplex virus infection mimicking cervical cancer.
Andrew Tomkins, Catherine White, Stephen Peter Higgins

BMJ Case Rep· June 2015

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A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage.
Tessa M Simone, Stephen P Higgins, Jaclyn Archambeault, Craig E Higgins, Roman G Ginnan, Paul J Higgins

Cell Signal· May 2015

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The basic helix-loop-helix/leucine zipper transcription factor USF2 integrates serum-induced PAI-1 expression and keratinocyte growth.
Li Qi, Craig E Higgins, Stephen P Higgins, Brian K Law, Tessa M Simone, Paul J Higgins

J Cell Biochem· October 2014

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Chemical Antagonists of Plasminogen Activator Inhibitor-1: Mechanisms of Action and Therapeutic Potential in Vascular Disease.
Tessa M Simone, Stephen P Higgins, Craig E Higgins, Michelle R Lennartz, Paul J Higgins

J Mol Genet Med· October 2014

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Rash and hepatitis within days of starting a new antiretroviral regimen: nevirapine hypersensitivity, secondary syphilis or both?
Cara J Saxon, Matthew R Helbert, Adeniyi J Komolafe, Stephen P Higgins

Int J STD AIDS· March 2014

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SERPINE1: A Molecular Switch in the Proliferation-Migration Dichotomy in Wound-"Activated" Keratinocytes.
Tessa M Simone, Craig E Higgins, Ralf-Peter Czekay, Brian K Law, Stephen P Higgins, Paul J Higgins

Adv Wound Care (New Rochelle)· March 2014

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BASHH's patient leaflets are produced through close collaboration between experts and patients.
Stephen P Higgins, Keith Radcliffe

BMJ· September 2013

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Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metalloproteinase Cascades.
Cynthia E Wilkins-Port, Stephen P Higgins, Craig E Higgins, Issey Kobori-Hotchkiss, Paul J Higgins

Biochem Res Int· August 2012

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Ureteral Obstruction-Induced Renal Fibrosis: An In Vivo Platform for Mechanistic Discovery and Therapeutic Intervention.
Amy D Dobberfuhl, Rohan Samarakoon, Craig E Higgins, Badar M Mian, Jessica M Overstreet, Stephen P Higgins, Paul J Higgins

Cell Dev Biol· July 2012

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TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis.
Rohan Samarakoon, Jessica M Overstreet, Stephen P Higgins, Paul J Higgins

Cell Tissue Res· January 2012

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Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression.
Rohan Samarakoon, Subhanir S Chitnis, Stephen P Higgins, Craig E Higgins, Joan C Krepinsky, Paul J Higgins

PLoS One· December 2011

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PAI-1: An Integrator of Cell Signaling and Migration.
Ralf-Peter Czekay, Cynthia E Wilkins-Port, Stephen P Higgins, Jennifer Freytag, Jessica M Overstreet, Craig E Higgins, Paul J Higgins

Int J Cell Biol· November 2011

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PAI-1 Expression Is Required for HDACi-Induced Proliferative Arrest in ras-Transformed Renal Epithelial Cells.
Stephen P Higgins, Craig E Higgins, Paul J Higgins

Int J Cell Biol· November 2011

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Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme.
Jennifer Downing, Penny A Cook, Hannah C E Madden, Penelope A Phillips-Howard, Stephen P Higgins

Sex Transm Infect· November 2010

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PAI-1 mediates the TGF-beta1+EGF-induced "scatter" response in transformed human keratinocytes.
Jennifer Freytag, Cynthia E Wilkins-Port, Craig E Higgins, Stephen P Higgins, Rohan Samarakoon, Paul J Higgins

J Invest Dermatol· September 2010

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