Publications by authors named "Stephen T Warren"

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Cross-species analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion.
Ryan H Purcell, Esra Sefik, Erica Werner, Alexia T King, Trenell J Mosley, Stephen T Warren

Sci Adv· August 2023

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Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion.
Ryan H Purcell, Esra Sefik, Erica Werner, Alexia T King, Trenell J Mosley, Stephen T Warren

bioRxiv· May 2023

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Descriptive analysis of seizures and comorbidities associated with fragile X syndrome.
Igor Albizua, Krista Charen, Lisa Shubeck, Amy Talboy, Elizabeth Berry-Kravis, Steven F Warren, Stephen T Warren

Mol Genet Genomic Med· August 2022

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Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons.
Alena Kozlova, Siwei Zhang, Alex V Kotlar, Brendan Jamison, Hanwen Zhang, Stephen T Warren

Am J Hum Genet· August 2022

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Identification of as a genetic modifier of fragile X-associated tremor/ataxia syndrome.
Ha Eun Kong, Junghwa Lim, Alexander Linsalata, Yunhee Kang, Indranil Malik, Stephen T Warren

Proc Natl Acad Sci U S A· May 2022

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Metabolic effects of the schizophrenia-associated 3q29 deletion.
Rebecca M Pollak, Ryan H Purcell, Timothy P Rutkowski, Tamika Malone, Kimberly J Pachura, Stephen T Warren

Transl Psychiatry· February 2022

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A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies.
Yunhee Kang, Ying Zhou, Yujing Li, Yanfei Han, Jie Xu, Stephen T Warren

Nat Neurosci· October 2021

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Identifying susceptibility genes for primary ovarian insufficiency on the high-risk genetic background of a fragile X premutation.
Cristina E Trevino, J Christopher Rounds, Krista Charen, Lisa Shubeck, Heather S Hipp, Stephen T Warren

Fertil Steril· September 2021

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Genetic contributors to risk of schizophrenia in the presence of a 22q11.2 deletion.
Isabelle Cleynen, Worrawat Engchuan, Matthew S Hestand, Tracy Heung, Aaron M Holleman, Stephen T Warren

Mol Psychiatry· August 2021

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Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis.
Nisha Raj, Zachary T McEachin, William Harousseau, Ying Zhou, Feiran Zhang, Stephen T Warren

Cell Rep· April 2021

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Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion.
Timothy P Rutkowski, Ryan H Purcell, Rebecca M Pollak, Stephanie M Grewenow, Georgette M Gafford, Stephen T Warren

Mol Psychiatry· March 2021

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Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons.
John D Graef, Hao Wu, Carrie Ng, Chicheng Sun, Vivian Villegas, Stephen T Warren

Eur J Neurosci· May 2020

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Analysis of the genomic expression profile in trisomy 18: insight into possible genes involved in the associated phenotypes.
Igor Albizua, Pankaj Chopra, Stephanie L Sherman, Michael J Gambello, Stephen T Warren

Hum Mol Genet· January 2020

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Voltage-Independent SK-Channel Dysfunction Causes Neuronal Hyperexcitability in the Hippocampus of Knock-Out Mice.
Pan-Yue Deng, Dan Carlin, Young Mi Oh, Leila K Myrick, Stephen T Warren

J Neurosci· January 2019

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Case-control meta-analysis of blood DNA methylation and autism spectrum disorder.
Shan V Andrews, Brooke Sheppard, Gayle C Windham, Laura A Schieve, Diana E Schendel, Stephen T Warren

Mol Autism· October 2018

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Reply to Plüss et al.: The strength of PEMapper/PECaller lies in unbiased calling using large sample sizes.
H Richard Johnston, Pankaj Chopra, Thomas S Wingo, Viren Patel, Michael P Epstein, Stephen T Warren

Proc Natl Acad Sci U S A· October 2017

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The Conserved, Disease-Associated RNA Binding Protein dNab2 Interacts with the Fragile X Protein Ortholog in Drosophila Neurons.
Rick S Bienkowski, Ayan Banerjee, J Christopher Rounds, Jennifer Rha, Omotola F Omotade, Stephen T Warren

Cell Rep· August 2017

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Reactivation of FMR1 by CRISPR/Cas9-Mediated Deletion of the Expanded CGG-Repeat of the Fragile X Chromosome.
Nina Xie, He Gong, Joshua A Suhl, Pankaj Chopra, Tao Wang, Stephen T Warren

PLoS One· June 2017

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Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.
Timothy P Rutkowski, Jason P Schroeder, Georgette M Gafford, Stephen T Warren, David Weinshenker

J Neurosci Res· May 2017

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PEMapper and PECaller provide a simplified approach to whole-genome sequencing.
H Richard Johnston, Pankaj Chopra, Thomas S Wingo, Viren Patel, , Stephen T Warren

Proc Natl Acad Sci U S A· March 2017

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Identification of consensus binding sites clarifies FMRP binding determinants.
Bart R Anderson, Pankaj Chopra, Joshua A Suhl, Stephen T Warren, Gary J Bassell

Nucleic Acids Res· August 2016

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A catalog of hemizygous variation in 127 22q11 deletion patients.
Matthew S Hestand, Beata A Nowakowska, Elfi Vergaelen, Jeroen Van Houdt, Luc Dehaspe, Stephen T Warren

Hum Genome Var· June 2016

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Single-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRP.
Joshua A Suhl, Stephen T Warren

J Exp Neurosci· January 2016

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Genome-wide association study of schizophrenia in Ashkenazi Jews.
Fernando S Goes, John McGrath, Dimitrios Avramopoulos, Paula Wolyniec, Mehdi Pirooznia, Stephen T Warren

Am J Med Genet B Neuropsychiatr Genet· December 2015

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A 3' untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR.
Joshua A Suhl, Ravi S Muddashetty, Bart R Anderson, Marius F Ifrim, Jeannie Visootsak, Stephen T Warren

Proc Natl Acad Sci U S A· November 2015

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