Publications by authors named "Steve Roof"

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Dynamic detection and reversal of myocardial ischemia using an artificially intelligent bioelectronic medicine.
Patrick D Ganzer, Masoud S Loeian, Steve R Roof, Bunyen Teng, Luan Lin

Sci Adv· January 2022

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Acute Effects of Pimobendan on Cardiac Function in Dogs With Tachycardia Induced Dilated Cardiomyopathy: A Randomized, Placebo-Controlled, Crossover Study.
Kaitlin Abbott-Johnson, Kursten V Pierce, Steve Roof, Carlos L Del Rio, Robert Hamlin

Front Vet Sci· July 2021

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NF-κB inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model.
Jennifer M Peterson, David J Wang, Vikram Shettigar, Steve R Roof, Benjamin D Canan

Nat Commun· August 2018

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CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction-A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat.
Steve R Roof, Yukie Ueyama, Reza Mazhari, Robert L Hamlin, J Craig Hartman

Front Physiol· November 2017

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Rationally engineered Troponin C modulates in vivo cardiac function and performance in health and disease.
Vikram Shettigar, Bo Zhang, Sean C Little, Hussam E Salhi, Brian J Hansen, Steve R Roof

Nat Commun· February 2016

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Obligatory role of neuronal nitric oxide synthase in the heart's antioxidant adaptation with exercise.
Steve R Roof, Hsiang-Ting Ho, Sean C Little, Joseph E Ostler, Elizabeth A Brundage

J Mol Cell Cardiol· April 2015

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Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation.
Jerry Curran, Lifei Tang, Steve R Roof, Sathya Velmurugan, Ashley Millard

PLoS One· December 2014

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Effects of insulin resistance on skeletal muscle growth and exercise capacity in type 2 diabetic mouse models.
Joseph E Ostler, Santosh K Maurya, Justin Dials, Steve R Roof, Steven T Devor

Am J Physiol Endocrinol Metab· March 2014

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Expression levels of sarcolemmal membrane repair proteins following prolonged exercise training in mice.
Jenna Alloush, Steve R Roof, Eric X Beck, Mark T Ziolo, Noah Weisleder

Indian J Biochem Biophys· October 2013

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Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies.
Joshua J Oaks, Ramasamy Santhanam, Christopher J Walker, Steve Roof, Jason G Harb

Blood· September 2013

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Diesterified nitrone rescues nitroso-redox levels and increases myocyte contraction via increased SR Ca(2+) handling.
Christopher J Traynham, Steve R Roof, Honglan Wang, Robert A Prosak, Lifei Tang

PLoS One· July 2013

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Neuronal nitric oxide synthase is indispensable for the cardiac adaptive effects of exercise.
Steve R Roof, Lifei Tang, Joseph E Ostler, Muthu Periasamy, Sandor Györke

Basic Res Cardiol· March 2013

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Effects of increased systolic Ca(2+) and β-adrenergic stimulation on Ca(2+) transient decline in NOS1 knockout cardiac myocytes.
Steve R Roof, Brandon J Biesiadecki, Jonathan P Davis, Paul M L Janssen, Mark T Ziolo

Nitric Oxide· December 2012

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Modulation of myocardial contraction by peroxynitrite.
Mark J Kohr, Steve R Roof, Jay L Zweier, Mark T Ziolo

Front Physiol· December 2012

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Effects of increased systolic Ca²⁺ and phospholamban phosphorylation during β-adrenergic stimulation on Ca²⁺ transient kinetics in cardiac myocytes.
Steve R Roof, Thomas R Shannon, Paul M L Janssen, Mark T Ziolo

Am J Physiol Heart Circ Physiol· October 2011

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cAMP-independent activation of protein kinase A by the peroxynitrite generator SIN-1 elicits positive inotropic effects in cardiomyocytes.
Mark J Kohr, Christopher J Traynham, Steve R Roof, Jonathan P Davis, Mark T Ziolo

J Mol Cell Cardiol· April 2010

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