Publications by authors named "Steve Stippec"

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Activation of WNK1 signaling through Piezo1.
Ji-Ung Jung, Steve Stippec, Melanie H Cobb

Proc Natl Acad Sci U S A· September 2025

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Kinase interaction analysis predicts actions of the WNK-OSR1/SPAK pathway.
Clinton A Taylor, Ji-Ung Jung, Sachith Gallolu Kankanamalage, Justin Li, Magdalena Grzemska, Steve Stippec

Commun Biol· September 2025

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Testis-specific serine kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors.
Magdalena Delgado, Zachary Gallegos, Steve Stippec, Kathleen McGlynn, Melanie H Cobb

J Biol Chem· June 2024

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Predictive and Experimental Motif Interaction Analysis Identifies Functions of the WNK-OSR1/SPAK Pathway.
Clinton A Taylor, Ji-Ung Jung, Sachith Gallolu Kankanamalage, Justin Li, Magdalena Grzemska, Steve Stippec

bioRxiv· June 2024

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The Cancer Testis Antigen Testis Specific Serine Kinase 6 (TSSK6) is abnormally expressed in colorectal cancer and promotes oncogenic behaviors.
Magdalena Delgado, Zachary Gallegos, Kathleen McGlynn, Steve Stippec, Melanie H Cobb

bioRxiv· April 2024

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Mimicking Protein Kinase C Phosphorylation Inhibits Arc/Arg3.1 Palmitoylation and Its Interaction with Nucleic Acids.
Barbara Barylko, Clinton A Taylor, Jason Wang, Svetlana Earnest, Steve Stippec

Int J Mol Sci· January 2024

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ERK2 Mutations Affect Interactions, Localization, and Dimerization.
Clinton A Taylor, Kevin W Cormier, Ana Martin-Vega, Svetlana Earnest, Steve Stippec

Biochemistry· May 2023

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Functional divergence caused by mutations in an energetic hotspot in ERK2.
Clinton A Taylor, Kevin W Cormier, Shannon E Keenan, Svetlana Earnest, Steve Stippec

Proc Natl Acad Sci U S A· July 2019

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OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant.
Clinton A Taylor, Sung-Wan An, Sachith Gallolu Kankanamalage, Steve Stippec, Svetlana Earnest

Proc Natl Acad Sci U S A· April 2018

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WNK1 is an unexpected autophagy inhibitor.
Sachith Gallolu Kankanamalage, A-Young Lee, Chonlarat Wichaidit, Andres Lorente-Rodriguez, Akansha M Shah, Steve Stippec

Autophagy· May 2017

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Assaying Protein Kinase Activity with Radiolabeled ATP.
Aroon S Karra, Steve Stippec, Melanie H Cobb

J Vis Exp· May 2017

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Multistep regulation of autophagy by WNK1.
Sachith Gallolu Kankanamalage, A-Young Lee, Chonlarat Wichaidit, Andres Lorente-Rodriguez, Akansha M Shah, Steve Stippec

Proc Natl Acad Sci U S A· December 2016

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Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.
Andrea C McReynolds, Aroon S Karra, Yan Li, Elias Daniel Lopez, Adrian G Turjanski, Steve Stippec

Biochemistry· March 2016

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Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals.
Samarpita Sengupta, Andrés Lorente-Rodríguez, Svetlana Earnest, Steve Stippec, Xiaofeng Guo

Proc Natl Acad Sci U S A· November 2013

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Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.
Samarpita Sengupta, Szu-Wei Tu, Kyle Wedin, Svetlana Earnest, Steve Stippec

J Biol Chem· November 2012

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Protein kinase WNK3 regulates the neuronal splicing factor Fox-1.
A-Young Lee, Wei Chen, Steve Stippec, Jon Self, Fan Yang

Proc Natl Acad Sci U S A· October 2012

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Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.
Charles J Heise, Bing-e Xu, Staci L Deaton, Seung-Kuy Cha, Chih-Jen Cheng, Steve Stippec

J Biol Chem· August 2010

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Regulation of a third conserved phosphorylation site in SGK1.
Wei Chen, Yue Chen, Bing-e Xu, Yu-Chi Juang, Steve Stippec

J Biol Chem· February 2009

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The roles of MAPKs in disease.
Michael C Lawrence, Arif Jivan, Chunli Shao, Lingling Duan, Daryl Goad, Steve Stippec

Cell Res· April 2008

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SLC26A9 is a Cl(-) channel regulated by the WNK kinases.
Michael R Dorwart, Nikolay Shcheynikov, Youxue Wang, Steve Stippec, Shmuel Muallem

J Physiol· October 2007

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Biological cross-talk between WNK1 and the transforming growth factor beta-Smad signaling pathway.
Byung-Hoon Lee, Wei Chen, Steve Stippec, Melanie H Cobb

J Biol Chem· June 2007

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WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism.
Bing-E Xu, Steve Stippec, Ahmed Lazrak, Chou-Long Huang, Melanie H Cobb

J Biol Chem· October 2005

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WNK1 activates SGK1 to regulate the epithelial sodium channel.
Bing-e Xu, Steve Stippec, Po-Yin Chu, Ahmed Lazrak, Xin-Ji Li

Proc Natl Acad Sci U S A· July 2005

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WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension.
Bing E Xu, Byung Hoon Lee, Xiaoshan Min, Lisa Lenertz, Charles J Heise, Steve Stippec

Cell Res· January 2005

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WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.
Bing-E Xu, Steve Stippec, Lisa Lenertz, Byung-Hoon Lee, Wei Zhang

J Biol Chem· February 2004

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