Publications by authors named "Steven A Yukl"

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Differential decreases in various HIV DNA regions and HIV transcripts after ART initiation during chronic infection.
Julie Janssens, Cordelia Isbell, Sun Jin Kim, Adam Wedrychowski, Alton Barbehenn, Steven A Yukl

J Virol· August 2025

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Longitudinal changes in the transcriptionally active and intact HIV reservoir after starting ART during acute infection.
Julie Janssens, Adam Wedrychowski, Sun Jin Kim, Cordelia Isbell, Rebecca Hoh, Steven A Yukl

J Virol· March 2025

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Mechanisms and efficacy of small molecule latency-promoting agents to inhibit HIV reactivation ex vivo.
Julie Janssens, Peggy Kim, Sun Jin Kim, Adam Wedrychowski, Gayatri N Kadiyala, Steven A Yukl

JCI Insight· August 2024

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Differential susceptibility of cells infected with defective and intact HIV proviruses to killing by obatoclax and other small molecules.
Gayatri Nikhila Kadiyala, Sushama Telwatte, Adam Wedrychowski, Julie Janssens, Sun Jin Kim, Steven A Yukl

AIDS· July 2024

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Adaptation of Droplet Digital PCR-Based HIV Transcription Profiling to Digital PCR and Association of HIV Transcription and Total or Intact HIV DNA.
Carolin Tumpach, Ajantha Rhodes, Youry Kim, Jesslyn Ong, Haoming Liu, Steven A Yukl

Viruses· July 2023

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Current HIV/SIV Reservoir Assays for Preclinical and Clinical Applications: Recommendations from the Experts 2022 NIAID Workshop Summary.
Brigitte E Sanders-Beer, Nancie M Archin, Zabrina L Brumme, Michael P Busch, Claire Deleage, Steven A Yukl

AIDS Res Hum Retroviruses· June 2023

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Transcriptomic Signatures of Human Immunodeficiency Virus Post-Treatment Control.
Adam Wedrychowski, Holly Anne Martin, Yijia Li, Sushama Telwatte, Gayatri Nikhila Kadiyala, Steven A Yukl

J Virol· January 2023

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New Assay Reveals Vast Excess of Defective over Intact HIV-1 Transcripts in Antiretroviral Therapy-Suppressed Individuals.
Holly Anne Martin, Gayatri Nikhila Kadiyala, Sushama Telwatte, Adam Wedrychowski, Tsui-Hua Chen, Steven A Yukl

J Virol· December 2022

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ABX464 Decreases the Total Human Immunodeficiency Virus (HIV) Reservoir and HIV Transcription Initiation in CD4+ T Cells From Antiretroviral Therapy-Suppressed Individuals Living With HIV.
Sara Moron-Lopez, Silvia Bernal, Joseph K Wong, Javier Martinez-Picado, Steven A Yukl

Clin Infect Dis· June 2022

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Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts.
Sushama Telwatte, Holly Anne Martin, Ryan Marczak, Parinaz Fozouni, Albert Vallejo-Gracia, Steven A Yukl

Methods· May 2022

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Common and Divergent Features of T Cells from Blood, Gut, and Genital Tract of Antiretroviral Therapy-Treated HIV Women.
Guorui Xie, Sara Moron-Lopez, David A Siegel, Kailin Yin, Anastasia Polos, Steven A Yukl

J Immunol· April 2022

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Novel assays to investigate the mechanisms of latent infection with HIV-2.
Michael D Lu, Sushama Telwatte, Nitasha Kumar, Fernanda Ferreira, Holly Anne Martin, Steven A Yukl

PLoS One· April 2022

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Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses.
Kevin B Einkauf, Matthew R Osborn, Ce Gao, Weiwei Sun, Xiaoming Sun, Steven A Yukl

Cell· January 2022

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Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response.
Guoxin Wu, Paul Zuck, Shih Lin Goh, Jeffrey M Milush, Poonam Vohra, Steven A Yukl

J Infect Dis· November 2021

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Tissue-specific differences in HIV DNA levels and mechanisms that govern HIV transcription in blood, gut, genital tract and liver in ART-treated women.
Sara Moron-Lopez, Guorui Xie, Peggy Kim, David A Siegel, Sulggi Lee, Steven A Yukl

J Int AIDS Soc· July 2021

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Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA.
Sushama Telwatte, Nitasha Kumar, Albert Vallejo-Gracia, G Renuka Kumar, Chuanyi M Lu, Steven A Yukl

J Virol Methods· June 2021

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Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART.
Charline Bacchus-Souffan, Mark Fitch, Jori Symons, Mohamed Abdel-Mohsen, Daniel B Reeves, Steven A Yukl

PLoS Pathog· January 2021

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Novel RT-ddPCR Assays for determining the transcriptional profile of SARS-CoV-2.
Sushama Telwatte, Nitasha Kumar, Albert Vallejo-Gracia, G Renuka Kumar, Chuanyi M Lu, Steven A Yukl

bioRxiv· January 2021

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Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103 and Gut CD4 T Cells.
Steven A Yukl, Shahzada Khan, Tsui-Hua Chen, Martin Trapecar, Frank Wu

J Virol· December 2020

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Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents.
Sushama Telwatte, Peggy Kim, Tsui-Hua Chen, Jeffrey M Milush, Ma Somsouk, Steven A Yukl

AIDS· November 2020

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Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals.
Sara Moron-Lopez, Sushama Telwatte, Indra Sarabia, Emilie Battivelli, Mauricio Montano, Steven A Yukl

PLoS Pathog· November 2020

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Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir.
Jason Neidleman, Xiaoyu Luo, Julie Frouard, Guorui Xie, Feng Hsiao, Steven A Yukl

Elife· September 2020

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HSF1 inhibition attenuates HIV-1 latency reversal mediated by several candidate LRAs In Vitro and Ex Vivo.
Andrew Timmons, Emily Fray, Mithra Kumar, Fengting Wu, Weiwei Dai, Steven A Yukl

Proc Natl Acad Sci U S A· July 2020

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Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.
Feng Hsiao, Julie Frouard, Andrea Gramatica, Guorui Xie, Sushama Telwatte, Steven A Yukl

PLoS Pathog· April 2020

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Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency.
Sushama Telwatte, Sara Morón-López, Dvir Aran, Peggy Kim, Christine Hsieh, Steven A Yukl

Retrovirology· November 2019

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