Publications by authors named "Steven Ackerley"

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Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria.
Gábor M Mórotz, Kurt J De Vos, Alessio Vagnoni, Steven Ackerley, Christopher E Shaw

Hum Mol Genet· May 2012

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VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis.
Kurt J De Vos, Gábor M Mórotz, Radu Stoica, Elizabeth L Tudor, Kwok-Fai Lau, Steven Ackerley

Hum Mol Genet· March 2012

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Dismutase-competent SOD1 mutant accumulation in myelinating Schwann cells is not detrimental to normal or transgenic ALS model mice.
Bradley J Turner, Steven Ackerley, Kay E Davies, Kevin Talbot

Hum Mol Genet· March 2010

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Role of axonal transport in neurodegenerative diseases.
Kurt J De Vos, Andrew J Grierson, Steven Ackerley, Christopher C J Miller

Annu Rev Neurosci· September 2008

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Steven Ackerley

Science· March 2008

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Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking.
Fiona M Laird, Mohamed H Farah, Steven Ackerley, Ahmet Hoke, Nicholas Maragakis

J Neurosci· February 2008

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Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.
Kurt J De Vos, Anna L Chapman, Maria E Tennant, Catherine Manser, Elizabeth L Tudor, Steven Ackerley

Hum Mol Genet· November 2007

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A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes.
Steven Ackerley, Paul A James, Arran Kalli, Sarah French, Kay E Davies

Hum Mol Genet· January 2006

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ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth.
Elizabeth L Tudor, Michael S Perkinton, Anja Schmidt, Steven Ackerley, Janet Brownlees

J Biol Chem· October 2005

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p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis.
Steven Ackerley, Andrew J Grierson, Steven Banner, Michael S Perkinton, Janet Brownlees

Mol Cell Neurosci· June 2004

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Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons.
Anirban R Saha, Josephine Hill, Michelle A Utton, Ayodeji A Asuni, Steven Ackerley

J Cell Sci· March 2004

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Identification of a novel, membrane-associated neuronal kinase, cyclin-dependent kinase 5/p35-regulated kinase.
Sashi Kesavapany, Kwok-Fai Lau, Steven Ackerley, Steven J Banner, Stephen J A Shemilt

J Neurosci· June 2003

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Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments.
Steven Ackerley, Paul Thornhill, Andrew J Grierson, Janet Brownlees, Brian H Anderton

J Cell Biol· May 2003

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Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport.
Janet Brownlees, Steven Ackerley, Andrew J Grierson, Nick J O Jacobsen, Kerry Shea

Hum Mol Genet· November 2002

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