Publications by authors named "Steven Almo"

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Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective.
Mona Seifert, Subhas C Bera, Pauline van Nies, Robert N Kirchdoerfer, Ashleigh Shannon, Thi-Tuyet-Nhung Le, Xiangzhi Meng, Hongjie Xia, James M Wood, Lawrence D Harris

October 2021

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Glypican-1 upregulation elicited in response to a cell-impermeable kinase inhibitor and its overexpression enhance HIV-1 infection.
Kelsey Vinzant, Natalia Cheshenko, Heng Pan, Ronald Cutler, Joshua N Buckler, Steven C Almo

bioRxiv· October 2025

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T-cell receptor/CD28-targeted immunotherapeutics selectively drive naive T-cell expansion to generate functional HIV-specific responses.
April L Mueller, Sara Lamcaj, Scott Garforth, Christopher Hiner, Darien Woodley, Steven C Almo

J Virol· September 2025

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Structural basis for sensitivity and acquired resistance of fungal cap guanine-N7 methyltransferases to the antifungal antibiotic sinefungin.
Daniel J Nilson, Beate Schwer, Steven C Almo, Stewart Shuman, Agnidipta Ghosh

Nucleic Acids Res· July 2025

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Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies.
Natalia E Ketaren, Peter C Fridy, Vladimir Malashkevich, Tanmoy Sanyal, Marc Brillantes, Steven C Almo

Structure· April 2025

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Transition State Analogs of Human DNPH1 Reveal Two Electrophile Migration Mechanisms.
Andrew G Wagner, Thomas B D Lang, Edward T Ledingham, Agnidipta Ghosh, Donovan Brooks, Steven C Almo

J Med Chem· February 2025

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Design of high-affinity binders to immune modulating receptors for cancer immunotherapy.
Wei Yang, Derrick R Hicks, Agnidipta Ghosh, Tristin A Schwartze, Brian Conventry, Steven C Almo

Nat Commun· February 2025

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Insights into the Interaction Landscape of the EVH1 Domain of Mena.
Lanette LaComb, Agnidipta Ghosh, Jeffrey B Bonanno, Daniel J Nilson, Alex J Poppel, Steven C Almo

Biochemistry· September 2024

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Structural and biochemical analysis of highly similar HLA-B allotypes differentially associated with type 1 diabetes.
Ruby Sharma, Nitin P Amdare, Agnidipta Ghosh, Jennifer Schloss, John Sidney, Steven C Almo

J Biol Chem· September 2024

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A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria.
Nicolas Grosjean, Estella F Yee, Desigan Kumaran, Kriti Chopra, Macon Abernathy, Steven C Almo

Nat Commun· April 2024

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Integrative Molecular Structure Elucidation and Construction of an Extended Metabolic Pathway Associated with an Ancient Innate Immune Response in COVID-19 Patients.
Samuele Sala, Philipp Nitschke, Reika Masuda, Nicola Gray, Nathan G Lawler, Steven C Almo

J Proteome Res· March 2024

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Computational simulations of bispecific T cell engagers by a multiscale model.
Zhaoqian Su, Steven C Almo, Yinghao Wu

Biophys J· January 2024

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Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion.
Jake C Lachowicz, David Lennox-Hvenekilde, Nils Myling-Petersen, Bo Salomonsen, Gijs Verkleij, Steven C Almo

J Am Chem Soc· January 2024

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Immune activation of the p75 neurotrophin receptor: implications in neuroinflammation.
Victor Danelon, Sarah C Garret-Thomson, Steven C Almo, Francis S Lee, Barbara L Hempstead

Front Mol Neurosci· December 2023

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Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity.
Yacoba V T Minnow, Vern L Schramm, Steven C Almo, Agnidipta Ghosh

Biochemistry· November 2023

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Author Correction: Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection.
Megan M Slough, Rong Li, Andrew S Herbert, Gorka Lasso, Ana I Kuehne, Steven C Almo

Nat Commun· September 2023

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Author Correction: Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.
Natalia Cheshenko, Jeffrey B Bonanno, Hans-Heinrich Hoffmann, Rohit K Jangra, Kartik Chandran, Steven C Almo

Commun Biol· August 2023

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Chemoenzymatic Synthesis of 3'-Deoxy-3',4'-didehydro-cytidine triphosphate (ddhCTP).
James H Lee, James M Wood, Steven C Almo, Gary B Evans, Lawrence D Harris

ACS Bio Med Chem Au· August 2023

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Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection.
Megan M Slough, Rong Li, Andrew S Herbert, Gorka Lasso, Ana I Kuehne, Steven C Almo

Nat Commun· July 2023

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Understanding the General Principles of T Cell Engagement by Multiscale Computational Simulations.
Zhaoqian Su, Steven C Almo, Yinghao Wu

bioRxiv· June 2023

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A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice.
Masayuki Kuraoka, Clare Burn Aschner, Ian W Windsor, Aakash Mahant Mahant, Scott J Garforth, Steven C Almo

J Clin Invest· February 2023

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SARS-CoV-2 multi-antigen protein microarray for detailed characterization of antibody responses in COVID-19 patients.
Alev Celikgil, Aldo B Massimi, Antonio Nakouzi, Natalia G Herrera, Nicholas C Morano, Steven C Almo

PLoS One· February 2023

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A glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm.
Richard T Piszczatowski, Emily Schwenger, Sriram Sundaravel, Catarina M Stein, Yang Liu, Steven C Almo

J Exp Med· November 2022

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Human immunomodulatory ligand B7-1 mediates synaptic remodeling via the p75 neurotrophin receptor.
Nicholas C Morano, Roshelle S Smith, Victor Danelon, Ryan Schreiner, Uttsav Patel, Steven C Almo

J Clin Invest· November 2022

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Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2.
Natalia Cheshenko, Jeffrey B Bonanno, Hans-Heinrich Hoffmann, Rohit K Jangra, Kartik Chandran, Steven C Almo

Commun Biol· October 2022

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HSMotifDiscover: identification of motifs in sequences composed of non-single-letter elements.
Vinod Kumar Singh, Rohan Misra, Steven C Almo, Ulrich G Steidl, Hannes E Bülow

Bioinformatics· August 2022

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