Publications by authors named "Steven Alvarez"

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Bimodality in Ras signaling originates from processivity of the Ras activator SOS without deterministic bistability.
Albert A Lee, Neil H Kim, Steven Alvarez, He Ren, Joseph B DeGrandchamp

Sci Adv· June 2024

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Bimodality in Ras signaling originates from processivity of the Ras activator SOS without classic kinetic bistability.
Albert A Lee, Neil H Kim, Steven Alvarez, He Ren, Joseph B DeGrandchamp

bioRxiv· July 2023

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A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane.
Chun-Wei Lin, Laura M Nocka, Brittany L Stinger, Joseph B DeGrandchamp, L J Nugent Lew, Steven Alvarez

Proc Natl Acad Sci U S A· May 2022

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Relating cellular signaling timescales to single-molecule kinetics: A first-passage time analysis of Ras activation by SOS.
William Y C Huang, Steven Alvarez, Yasushi Kondo, John Kuriyan, Jay T Groves

Proc Natl Acad Sci U S A· November 2021

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Stochasticity and positive feedback enable enzyme kinetics at the membrane to sense reaction size.
Albert A Lee, William Y C Huang, Scott D Hansen, Neil H Kim, Steven Alvarez

Proc Natl Acad Sci U S A· November 2021

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Raf promotes dimerization of the Ras G-domain with increased allosteric connections.
Morgan R Packer, Jillian A Parker, Jean K Chung, Zhenlu Li, Young Kwang Lee, Steven Alvarez

Proc Natl Acad Sci U S A· March 2021

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Nanopore-mediated protein delivery enabling three-color single-molecule tracking in living cells.
Zhongwen Chen, Yuhong Cao, Chun-Wei Lin, Steven Alvarez, Dongmyung Oh

Proc Natl Acad Sci U S A· February 2021

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A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS.
William Y C Huang, Steven Alvarez, Yasushi Kondo, Young Kwang Lee, Jean K Chung

Science· March 2019

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K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions.
Jean K Chung, Young Kwang Lee, John-Paul Denson, William K Gillette, Steven Alvarez

Biophys J· January 2018

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Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.
Young Kwang Lee, Shalini T Low-Nam, Jean K Chung, Scott D Hansen, Hiu Yue Monatrice Lam, Steven Alvarez

Nat Commun· April 2017

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One-way membrane trafficking of SOS in receptor-triggered Ras activation.
Sune M Christensen, Hsiung-Lin Tu, Jesse E Jun, Steven Alvarez, Meredith G Triplet

Nat Struct Mol Biol· September 2016

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Enhancing the performance of solution-processed n-type organic field-effect transistors by blending with molecular "aligners".
Yue Zhang, David Hanifi, Eunhee Lim, Slim Chourou, Steven Alvarez

Adv Mater· February 2014

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Spin-cast bulk heterojunction solar cells: a dynamical investigation.
Kang Wei Chou, Buyi Yan, Ruipeng Li, Er Qiang Li, Kui Zhao, Steven Alvarez

Adv Mater· April 2013

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Charge transport anisotropy in n-type disk-shaped triphenylene-tris(aroyleneimidazole)s.
Yue Zhang, David Hanifi, Steven Alvarez, Francisco Antonio, Andrew Pun

Org Lett· December 2011

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