Publications by authors named "Steven C Ley"

Claim this Profile
C
CARD14 signaling in intestinal epithelial cells induces intestinal inflammation and intestinal transit delay.
Aigerim Aidarova, Marieke Carels, Mira Haegman, Yasmine Driege, Steven Timmermans, Steven C Ley

EMBO Mol Med· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bioinformatic analysis of molecular characteristics and oncogenic features of CARD14 in human cancer.
Daniil Bespalov, Dayana Pino, Sònia Vidal-Guirao, Júlia Franquesa, Daniel Lopez-Ramajo, Steven C Ley

Sci Rep· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation.
Paul A O'Sullivan, Aigerim Aidarova, Inna S Afonina, Joan Manils, Teresa L M Thurston, Steven C Ley

Biochem J· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
p38γ and p38δ modulate innate immune response by regulating MEF2D activation.
Alejandra Escós, Ester Diaz-Mora, Michael Pattison, Pilar Fajardo, Diego González-Romero, Steven C Ley

Elife· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages.
Simon Rousseau, Matoula Papoutsopoulou, Antony Symons, Dorthe Cook, John M Lucocq, Steven C Ley

J Cell Sci· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages.
Louise Blair, Michael J Pattison, Probir Chakravarty, Stamatia Papoutsopoulou, Latifa Bakiri, Steven C Ley

J Immunol· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TPL-2 kinase induces phagosome acidification to promote macrophage killing of bacteria.
Felix Breyer, Anetta Härtlova, Teresa Thurston, Helen R Flynn, Probir Chakravarty, Steven C Ley

EMBO J· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CARD14 signalling in keratinocytes induces TNF-dependent skin and systemic inflammation.
Joan Manils, Louise V Webb, Ashleigh Howes, Julia Janzen, Stefan Boeing, Steven C Ley

Elife· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
ABIN-2, of the TPL-2 Signaling Complex, Modulates Mammalian Inflammation.
Louise V Webb, Sonia Ventura, Steven C Ley

Trends Immunol· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism.
Sambit K Nanda, Tsunehisa Nagamori, Mark Windheim, Sylvia Amu, Gabriella Aviello, Steven C Ley

J Immunol· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation.
Sonia Ventura, Florencia Cano, Yashaswini Kannan, Felix Breyer, Michael J Pattison, Steven C Ley

J Exp Med· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate.
Sandra Kümper, Thorsten Gantke, Chao-Sheng Chen, Yasmina Soneji, Michael J Pattison, Steven C Ley

Biochem J· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Protein CoAlation: a redox-linked post-translational modification.
Steven C Ley, Luiz Pedro S de Carvalho

Biochem J· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus.
Yashaswini Kannan, Lewis J Entwistle, Victoria S Pelly, Jimena Perez-Lloret, Alan W Walker, Steven C Ley

PLoS Pathog· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells.
Yashaswini Kannan, Yanda Li, Stephanie M Coomes, Isobel S Okoye, Victoria S Pelly, Steven C Ley

J Allergy Clin Immunol· February 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.
Michael J Pattison, Olivia Mitchell, Helen R Flynn, Chao-Sheng Chen, Huei-Ting Yang, Steven C Ley

Biochem J· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TPL-2 Regulates Macrophage Lipid Metabolism and M2 Differentiation to Control TH2-Mediated Immunopathology.
Yashaswini Kannan, Jimena Perez-Lloret, Yanda Li, Lewis J Entwistle, Hania Khoury, Stanley Ching-Cheng Huang, Steven C Ley

PLoS Pathog· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TNF activation of NF-κB is essential for development of single-positive thymocytes.
Louise V Webb, Steven C Ley, Benedict Seddon

J Exp Med· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.
Ashleigh Howes, Paul A O'Sullivan, Felix Breyer, Ashavari Ghose, Li Cao, Steven C Ley

Biochem J· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
Emilie Jacque, Edina Schweighoffer, Victor L J Tybulewicz, Steven C Ley

J Exp Med· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Priming IKKβ kinase for action.
Steven C Ley, Rudi Beyaert

Biochem J· October 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IKK-induced NF-κB1 p105 proteolysis is critical for B cell antibody responses to T cell-dependent antigen.
Emilie Jacque, Edina Schweighoffer, Alexander Visekruna, Stamatia Papoutsopoulou, Julia Janzen, Steven C Ley

J Exp Med· September 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases.
Abduelhakem Ben-Addi, Agnes Mambole-Dema, Christine Brender, Stephen R Martin, Julia Janzen, Steven C Ley

Proc Natl Acad Sci U S A· June 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
Srividya Sriskantharajah, Eva Gückel, Niki Tsakiri, Katrin Kierdorf, Christine Brender, Steven C Ley

J Immunol· April 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
NF-κB signaling mediates homeostatic maturation of new T cells.
Ana Silva, Georgina Cornish, Steven C Ley, Benedict Seddon

Proc Natl Acad Sci U S A· March 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis