Publications by authors named "Steven C Rothman"

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Engineering two species of yeast as cell factories for 2'-fucosyllactose.
Kerry Hollands, Christopher M Baron, Katharine J Gibson, Kristen J Kelly, Elizabeth A Krasley, Steven C Rothman

Metab Eng· March 2019

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Development of dietary soluble fibres by enzymatic synthesis and assessment of their digestibility in in vitro, animal and randomised clinical trial models.
Oliver Hasselwander, Robert DiCosimo, Zheng You, Qiong Cheng, Steven C Rothman

Int J Food Sci Nutr· November 2017

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Determination of kinetics and the crystal structure of a novel type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase from Streptococcus pneumoniae.
Jerome de Ruyck, Matthew W Janczak, Syam Sundar Neti, Steven C Rothman, Heidi L Schubert

Chembiochem· July 2014

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Crystal structure of type 2 isopentenyl diphosphate isomerase from Thermus thermophilus in complex with inorganic pyrophosphate.
Jérôme de Ruyck, Jenny Pouyez, Steven C Rothman, Dale Poulter, Johan Wouters

Biochemistry· September 2008

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Type II isopentenyl diphosphate isomerase: irreversible inactivation by covalent modification of flavin.
Steven C Rothman, Jonathan B Johnston, Sungwon Lee, Joel R Walker, C Dale Poulter

J Am Chem Soc· April 2008

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Synthesis and evaluation of substrate analogues as mechanism-based inhibitors of type II isopentenyl diphosphate isomerase.
Joel R Walker, Steven C Rothman, C Dale Poulter

J Org Chem· January 2008

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Type-2 isopentenyl diphosphate isomerase. Mechanistic studies with cyclopropyl and epoxy analogues.
Jonathan B Johnston, Joel R Walker, Steven C Rothman, C Dale Poulter

J Am Chem Soc· June 2007

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Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species.
Steven C Rothman, Travis R Helm, C Dale Poulter

Biochemistry· May 2007

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Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics.
Jérôme de Ruyck, Steven C Rothman, C Dale Poulter, Johan Wouters

Biochem Biophys Res Commun· December 2005

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Directed evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase.
Steven C Rothman, Mark Voorhies, Jack F Kirsch

Protein Sci· March 2004

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The Saccharomyces cerevisiae COQ6 gene encodes a mitochondrial flavin-dependent monooxygenase required for coenzyme Q biosynthesis.
Peter Gin, Adam Y Hsu, Steven C Rothman, Tanya Jonassen, Peter T Lee

J Biol Chem· July 2003

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How does an enzyme evolved in vitro compare to naturally occurring homologs possessing the targeted function? Tyrosine aminotransferase from aspartate aminotransferase.
Steven C Rothman, Jack F Kirsch

J Mol Biol· March 2003

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Quantitative chimeric analysis of six specificity determinants that differentiate Escherichia coli aspartate from tyrosine aminotransferase.
Wendy A Shaffer, Tinh N Luong, Steven C Rothman, Jack F Kirsch

Protein Sci· December 2002

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