Publications by authors named "Steven D Rhodes"

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A haploinsufficiency restoration strategy corrects neurobehavioral deficits in Nf1+/- mice.
Su Jung Park, Jodi L Lukkes, Ka-Kui Chan, Hayley P Drozd, Callie B Burgin, Steven D Rhodes

J Clin Invest· July 2025

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TGFβ-dependent signaling drives tumor growth and aberrant extracellular matrix dynamics in NF1-associated plexiform neurofibroma.
Mohannad Abu-Sultanah, Zhuan Zhou, Chunhui Jiang, Dana K Mitchell, Waylan K Bessler, Steven D Rhodes

Sci Adv· June 2025

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An induced pluripotent stem cell model of Schwann cell differentiation reveals NF2- related gene regulatory networks.
Olivia Lazaro, Sihong Li, William Carter, Jake Smiley, Oluwamayowa Awosika, Steven D Rhodes

Res Sq· June 2025

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PLK1 Inhibition Induces Synthetic Lethality in Fanconi Anemia Pathway-Deficient Acute Myeloid Leukemia.
Aditya S Sheth, Ka-Kui Chan, Sheng Liu, Jun Wan, Steve P Angus, Steven D Rhodes

Cancer Res Commun· April 2025

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Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial.
Andrea M Gross, Geraldine O'Sullivan Coyne, Eva Dombi, Cecilia Tibery, William G Herrick, Steven D Rhodes

Nat Med· January 2025

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Efficacy of the Allosteric MEK Inhibitor Trametinib in Relapsed and Refractory Juvenile Myelomonocytic Leukemia: a Report from the Children's Oncology Group.
Elliot Stieglitz, Alex G Lee, Steven P Angus, Christopher Davis, Donald A Barkauskas, Steven D Rhodes

Cancer Discov· September 2024

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A novel induced pluripotent stem cell model of Schwann cell differentiation reveals - related gene regulatory networks of the extracellular matrix.
Olivia Lazaro, Sihong Li, William Carter, Oluwamayowa Awosika, Sylvia Robertson, Steven D Rhodes

bioRxiv· July 2024

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Correction: Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler, Steven D Rhodes

Clin Cancer Res· May 2024

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Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of -null, melanoma to BRAF/MEK inhibition.
Evan DuBose, Samantha M Bevill, Dana K Mitchell, Noah Sciaky, Brian T Golitz, Steven D Rhodes

Front Oncol· May 2024

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Spatial Gene-Expression Profiling Unveils Immuno-oncogenic Programs of NF1-Associated Peripheral Nerve Sheath Tumor Progression.
Dana K Mitchell, Breanne Burgess, Emily E White, Abbi E Smith, Elizabeth A Sierra Potchanant, Steven D Rhodes

Clin Cancer Res· March 2024

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Recommendations for the collection and annotation of biosamples for analysis of biomarkers in neurofibromatosis and schwannomatosis clinical trials.
R Taylor Sundby, Steven D Rhodes, Edina Komlodi-Pasztor, Herb Sarnoff, Vito Grasso

Clin Trials· February 2024

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The +/- Immune Microenvironment: Dueling Roles in Neurofibroma Development and Malignant Transformation.
Emily E White, Steven D Rhodes

Cancers (Basel)· February 2024

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Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Alyssa C Flint, Dana K Mitchell, Steven P Angus, Abbi E Smith, Waylan Bessler, Steven D Rhodes

Clin Cancer Res· September 2023

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RAS Signaling Gone Awry in the Skin: The Complex Role of RAS in Cutaneous Neurofibroma Pathogenesis, Emerging Biological Insights.
Steven D Rhodes, Frank McCormick, Ross L Cagan, Annette Bakker, Verena Staedtke

J Invest Dermatol· August 2023

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Target Product Profile for Cutaneous Neurofibromas: Clinical Trials to Prevent, Arrest, or Regress Cutaneous Neurofibromas.
Ina Ly, Carlos G Romo, Sally Gottesman, Kristen M Kelly, Deanna Kornacki, Steven D Rhodes

J Invest Dermatol· August 2023

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Existing and Developing Preclinical Models for Neurofibromatosis Type 1-Related Cutaneous Neurofibromas.
Verena Staedtke, Piotr Topilko, Lu Q Le, Kevin Grimes, David A Largaespada, Steven D Rhodes

J Invest Dermatol· August 2023

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A Call for Discovery and Therapeutic Development for Cutaneous Neurofibromas.
Jaishri O Blakeley, Lu Q Le, Sang Y Lee, Ina Ly, Steven D Rhodes

J Invest Dermatol· August 2023

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Advances in Targeted Therapy for Neurofibromatosis Type 2 (NF2)-Associated Vestibular Schwannomas.
Evan C Cumpston, Steven D Rhodes, Charles W Yates

Curr Oncol Rep· May 2023

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Correction: Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Silpa Gampala, Fenil Shah, Chi Zhang, Steven D Rhodes, Olivia Babb

Br J Cancer· October 2022

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SIK2 kinase synthetic lethality is driven by spindle assembly defects in FANCA-deficient cells.
Ka-Kui Chan, Zahi Abdul-Sater, Aditya Sheth, Dana K Mitchell, Richa Sharma, Steven D Rhodes

Mol Oncol· February 2022

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Exploring transcriptional regulators Ref-1 and STAT3 as therapeutic targets in malignant peripheral nerve sheath tumours.
Silpa Gampala, Fenil Shah, Chi Zhang, Steven D Rhodes, Olivia Babb

Br J Cancer· April 2021

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Cabozantinib for neurofibromatosis type 1-related plexiform neurofibromas: a phase 2 trial.
Michael J Fisher, Chie-Schin Shih, Steven D Rhodes, Amy E Armstrong, Pamela L Wolters

Nat Med· January 2021

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A molecular basis for neurofibroma-associated skeletal manifestations in NF1.
Yun Ma, Andrea M Gross, Eva Dombi, Alexander Pemov, Kwangmin Choi, Steven D Rhodes

Genet Med· November 2020

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Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17.
Julie A Mund, SuJung Park, Abbi E Smith, Yongzheng He, Li Jiang, Steven D Rhodes

J Biol Chem· November 2020

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Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1.
Julie A Mund, SuJung Park, Abbi E Smith, Yongzheng He, Li Jiang, Steven D Rhodes

J Biol Chem· July 2020

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