Publications by authors named "Steven DeMarco"

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Discovery of Zilucoplan: A Complement C5 Inhibitor for Treatment of Anti-Acetylcholine Receptor (AChR) Antibody-Positive Generalized Myasthenia Gravis (gMG).
Ping Ye, Robert P Hammer, Zhaolin Wang, Ketki Dhamnaskar, Michelle Hoarty, Steven J DeMarco

J Med Chem· December 2025

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Preclinical studies of gene replacement therapy for CDKL5 deficiency disorder.
Gregory Voronin, Jana Narasimhan, Jamila Gittens, Josephine Sheedy, Philip Lipari, Steven DeMarco

Mol Ther· October 2024

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AAV2-hAADC (Eladocagene Exuparvovec) Biodistribution and Expression: Superiority of Intraputaminal versus Intracerebroventricular and Intrathecal (Lumbar) Routes of Administration.
David R Compton, Steven J DeMarco, Padmaja Yalamanchili

Int J Toxicol· February 2023

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Development of peptide therapeutics: A nonclinical safety assessment perspective.
Mayur S Mitra, Steven DeMarco, Brad Holub, Lakshmanan Thiruneelakantapillai, Evan A Thackaberry

Regul Toxicol Pharmacol· November 2020

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Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of sepsis.
Ravi Shankar Keshari, Robert Silasi, Narcis Ioan Popescu, Maulin Mukeshchandra Patel, Hala Chaaban, Steven J DeMarco

Proc Natl Acad Sci U S A· August 2017

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Peptidomimetic antibiotics target outer-membrane biogenesis in Pseudomonas aeruginosa.
Nityakalyani Srinivas, Peter Jetter, Bernhard J Ueberbacher, Martina Werneburg, Katja Zerbe, Steven J DeMarco

Science· February 2010

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Discovery of novel, highly potent and selective beta-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles.
Steven J DeMarco, Heiko Henze, Alexander Lederer, Kerstin Moehle, Reshmi Mukherjee

Bioorg Med Chem· December 2006

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Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.
Geoffrey M Goellner, Steven J DeMarco, Emanuel E Strehler

Ann N Y Acad Sci· April 2003

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Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.
David Krizaj, Steven J Demarco, Juliette Johnson, Emanuel E Strehler, David R Copenhagen

J Comp Neurol· September 2002

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Plasma membrane Ca2+ ATPase isoform 2b interacts preferentially with Na+/H+ exchanger regulatory factor 2 in apical plasma membranes.
Steven J DeMarco, Michael C Chicka, Emanuel E Strehler

J Biol Chem· March 2002

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Bradykinin and ATP accelerate Ca(2+) efflux from rat sensory neurons via protein kinase C and the plasma membrane Ca(2+) pump isoform 4.
Yuriy M Usachev, Steven J DeMarco, Colin Campbell, Emanuel E Strehler, Stanley A Thayer

Neuron· January 2002

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