Publications by authors named "Steven Eck"

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I
IPH5201, an Anti-CD39 mAb, as Monotherapy or in Combination with Durvalumab in Advanced Solid Tumors.
John Powderly, Martina Imbimbo, Antoine Italiano, Patricia Martin-Romano, Meredith McKean, Steven Eck

Cancer Res Commun· September 2025

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Flow cytometry assay modifications: Recommendations for method validation based on CLSI H62 guidelines.
Sara A Monaghan, Steven Eck, Silvia Bunting, Xiangyang X Dong, Robert J Durso

Cytometry B Clin Cytom· May 2025

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2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bioanalysis by Multiple Platforms; Super Sensitive ADA/NAb LBA ( - Recommendations on Advanced Strategies for Biomarkers, IVD/CDx Assays (BAV), Cell Based Assays (CBA), and Ligand-Binding Assays (LBA) - Regulatory Agencies' Input on Biomarkers, IVD/CDx, and Biomarker Assay Validation).
Nicoletta Bivi, Danielle Graham, Laura Joglekar, Kristina McGuire, Jeroen Stoop, Steven Eck

Bioanalysis· February 2025

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2023 White Paper on Recent Issues in Bioanalysis: EU IVDR 2017/746 Implementation/Impact, IVD/CDx/CLIA Approved Assays, High Dimensional Cytometry, Multiplexing Technologies, LBA Tissue Analysis, Vaccine Study Endpoints, Cell-Based Assays for Biomarkers, Cell Therapy and Vaccines ( - Recommendations on Development & Validation of Biomarkers, IVD, CDx, Cell-Based, Flow Cytometry, Ligand-Binding and Enzyme Assays; Advanced Critical Reagents Strategies).
Olga Kholmanskikh, Yow-Ming Wang, Sarah Hersey, Meenu Wadhwa, Katherine Block, Steven Eck

Bioanalysis· June 2024

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A comparative study of blood cell count in four automated hematology analyzers: An evaluation of the impact of preanalytical factors.
Annika Åstrand, Cecilia Wingren, Claire Walton, Johan Mattsson, Komal Agrawal, Steven Eck

PLoS One· May 2024

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Correction: Flow Cytometry Method Validation Protocols.
Nithianandan Selliah, Veronica Nash, Steven Eck, Cherie Green, Teri Oldaker

Curr Protoc· January 2024

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2022 White Paper on Recent Issues in Bioanalysis: Enzyme Assay Validation, BAV for Primary End Points, Vaccine Functional Assays, Cytometry in Tissue, LBA in Rare Matrices, Complex NAb Assays, Spectral Cytometry, Endogenous Analytes, Extracellular Vesicles - Recommendations on Biomarkers/CDx, Flow Cytometry, Ligand-Binding Assays Development & Validation; Emerging Technologies; Critical Reagents Deep Characterization.
Giane Sumner, Steve Keller, James Huleatt, Roland F Staack, Leslie Wagner, Steven Eck

Bioanalysis· August 2023

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Flow Cytometry Method Validation Protocols.
Nithianandan Selliah, Veronica Nash, Steven Eck, Cherie Green, Teri Oldaker

Curr Protoc· August 2023

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First-in-human study of oleclumab, a potent, selective anti-CD73 monoclonal antibody, alone or in combination with durvalumab in patients with advanced solid tumors.
Johanna Bendell, Patricia LoRusso, Michael Overman, Anne M Noonan, Dong-Wan Kim, Steven Eck

Cancer Immunol Immunother· July 2023

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2021 White Paper on Recent Issues in Bioanalysis: ISR for Biomarkers, Liquid Biopsies, Spectral Cytometry, Inhalation/Oral & Multispecific Biotherapeutics, Accuracy/LLOQ for Flow Cytometry ( - Recommendations on Biomarkers/CDx Assays Development & Validation, Cytometry Validation & Innovation, Biotherapeutics PK LBA Regulated Bioanalysis, Critical Reagents & Positive Controls Generation).
Sarah Hersey, Steve Keller, Joel Mathews, Lindsay King, Abbas Bandukwala, Steven Eck

Bioanalysis· May 2022

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2020 White Paper on Recent Issues in Bioanalysis: BAV Guidance, CLSI H62, Biotherapeutics Stability, Parallelism Testing, CyTOF and Regulatory Feedback ( - Recommendations on Biotherapeutics Stability, PK LBA Regulated Bioanalysis, Biomarkers Assays, Cytometry Validation & Innovation - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine).
Susan Spitz, Yan Zhang, Sally Fischer, Kristina McGuire, Ulrike Sommer, Steven Eck

Bioanalysis· March 2021

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High-sensitivity flow cytometric assays: Considerations for design control and analytical validation for identification of Rare events.
Ulrike Sommer, Steven Eck, Laura Marszalek, Jennifer J Stewart, Jolene Bradford

Cytometry B Clin Cytom· January 2021

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Best practices for the development, analytical validation and clinical implementation of flow cytometric methods for chimeric antigen receptor T cell analyses.
Ghanashyam Sarikonda, Mélissa Mathieu, Mahwish Natalia, Anil Pahuja, Qiong Xue, Steven Eck

Cytometry B Clin Cytom· January 2021

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Safety and Clinical Activity of MEDI0562, a Humanized OX40 Agonist Monoclonal Antibody, in Adult Patients with Advanced Solid Tumors.
Bonnie S Glisson, Rom S Leidner, Robert L Ferris, John Powderly, Naiyer A Rizvi, Steven Eck

Clin Cancer Res· October 2020

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Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops.
Kamila Czechowska, Joanne Lannigan, Lili Wang, Judith Arcidiacono, Thomas M Ashhurst, Steven Eck

Cytometry A· June 2019

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A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity.
Jodi L Karnell, Marius Albulescu, Stacey Drabic, Liangwei Wang, Rachel Moate, Steven C Eck

Sci Transl Med· April 2019

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Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.
Bo Chen, Katherine A Vousden, Brian Naiman, Sean Turman, Hong Sun, Steven Eck, Holly Koelkebeck, Roland Kolbeck

Ann Rheum Dis· February 2019

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Flow Cytometry Method Validation Protocols.
Nithianandan Selliah, Steven Eck, Cherie Green, Teri Oldaker, Jennifer Stewart

Curr Protoc Cytom· January 2019

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Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion Protein.
Michael D Oberst, Catherine Augé, Chad Morris, Stacy Kentner, Kathy Mulgrew, Steven Eck

Mol Cancer Ther· May 2018

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Ex vivo expanded human CD4+CD25+Foxp3+ regulatory T cells prevent lethal xenogenic graft versus host disease (GVHD).
Tinghua Cao, Allis Soto, Wei Zhou, Weihong Wang, Steven Eck

Cell Immunol· June 2009

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Developmental alterations in thymocyte sensitivity are actively regulated by MHC class II expression in the thymic medulla.
Steven C Eck, Peimin Zhu, Marion Pepper, Steven J Bensinger, Bruce D Freedman

J Immunol· February 2006

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