Publications by authors named "Steven F Lee"

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Stress-Induced Reorganization of Proteasomes Through Diffusion and Cytoskeleton-Dependent Mechanisms.
Michael J Morten, Yu Zhang, Bing Li, Jonathan X Meng, Kun Jiang, Ji-Eun Lee, Steven F Lee

Small· November 2025

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Large-scale visualization of α-synuclein oligomers in Parkinson's disease brain tissue.
Rebecca Andrews, Bin Fu, Christina E Toomey, Jonathan C Breiter, Joanne Lachica, Steven F Lee

Nat Biomed Eng· October 2025

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Neurodegeneration emerges at a cellular tipping point between aggregate accumulation and removal.
Matthew W Cotton, Shriram Venkatesan, Joseph S Beckwith, Dorothea Böken, Catherine K Xu, Steven F Lee

bioRxiv· October 2025

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DHPSFU: a Fiji plugin for fast and accurate double helix-PSF 3D single-molecule localisation microscopy.
Ziwei Zhang, Aleksandra Ochirova, Siqi Liu, Alex D Herbert, Yunzhao Wu, Steven F Lee

Sci Rep· August 2025

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3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain.
Sam Daly, Edita Bulovaite, Anoushka Handa, Katie Morris, Leila Muresan, Steven F Lee

ACS Chem Neurosci· January 2025

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POLCAM: instant molecular orientation microscopy for the life sciences.
Ezra Bruggeman, Oumeng Zhang, Lisa-Maria Needham, Markus Körbel, Sam Daly, Steven F Lee

Nat Methods· October 2024

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Single-molecule digital sizing of proteins in solution.
Georg Krainer, Raphael P B Jacquat, Matthias M Schneider, Timothy J Welsh, Jieyuan Fan, Steven F Lee

Nat Commun· September 2024

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Single-Molecule Stoichiometry of Supramolecular Complexes.
Alan McLean, Renata L Sala, Brooke W Longbottom, Alexander R Carr, Jade A McCune, Steven F Lee

J Am Chem Soc· May 2024

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RASP: Optimal Single Puncta Detection in Complex Cellular Backgrounds.
Bin Fu, Emma E Brock, Rebecca Andrews, Jonathan C Breiter, Ru Tian, Steven F Lee

J Phys Chem B· April 2024

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High-density volumetric super-resolution microscopy.
Sam Daly, João Ferreira Fernandes, Ezra Bruggeman, Anoushka Handa, Ruby Peters, Steven F Lee

Nat Commun· March 2024

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Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Anna H Lippert, Christopher Paluch, Meike Gaglioni, Mai T Vuong, James McColl, Steven F Lee

Immunity· February 2024

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Antigen discrimination by T cells relies on size-constrained microvillar contact.
Edward Jenkins, Markus Körbel, Caitlin O'Brien-Ball, James McColl, Kevin Y Chen, Steven F Lee

Nat Commun· March 2023

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resPAINT: Accelerating Volumetric Super-Resolution Localisation Microscopy by Active Control of Probe Emission.
Edward W Sanders, Alexander R Carr, Ezra Bruggeman, Markus Körbel, Sarah I Benaissa, Steven F Lee

Angew Chem Int Ed Engl· October 2022

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resPAINT: Accelerating Volumetric Super-Resolution Localisation Microscopy by Active Control of Probe Emission.
Edward W Sanders, Alexander R Carr, Ezra Bruggeman, Markus Körbel, Sarah I Benaissa, Steven F Lee

Angew Chem Weinheim Bergstr Ger· October 2022

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Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses.
Jonathan X Meng, Yu Zhang, Dominik Saman, Arshad M Haider, Suman De, Steven F Lee

Nat Commun· May 2022

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A Comparative Study of High-Contrast Fluorescence Lifetime Probes for Imaging Amyloid in Tissue.
Felix Gorka, Sam Daly, Colin M Pearson, Edita Bulovaite, Yu P Zhang, Steven F Lee

J Phys Chem B· December 2021

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Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.
Anna Vilalta, Ye Zhou, Jean Sevalle, Jennifer K Griffin, Kanayo Satoh, Steven F Lee

J Biol Chem· August 2021

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Quantum Emitter Localization in Layer-Engineered Hexagonal Boron Nitride.
James Callum Stewart, Ye Fan, John S H Danial, Alexander Goetz, Adarsh S Prasad, Steven F Lee

ACS Nano· August 2021

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Single-molecule fluorescence detection of a tricyclic nucleoside analogue.
George N Samaan, Mckenzie K Wyllie, Julian M Cizmic, Lisa-Maria Needham, David Nobis, Steven F Lee

Chem Sci· December 2020

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vLUME: 3D virtual reality for single-molecule localization microscopy.
Alexander Spark, Alexandre Kitching, Daniel Esteban-Ferrer, Anoushka Handa, Alexander R Carr, Steven F Lee

Nat Methods· November 2020

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A Comparative Photophysical Study of Structural Modifications of Thioflavin T-Inspired Fluorophores.
Lisa-Maria Needham, Judith Weber, Colin M Pearson, Dung T Do, Felix Gorka, Steven F Lee

J Phys Chem Lett· October 2020

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Single-molecule visualization of DNA G-quadruplex formation in live cells.
Marco Di Antonio, Aleks Ponjavic, Antanas Radzevičius, Rohan T Ranasinghe, Marco Catalano, Steven F Lee

Nat Chem· September 2020

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Rational design of a conformation-specific antibody for the quantification of Aβ oligomers.
Francesco A Aprile, Pietro Sormanni, Marina Podpolny, Shianne Chhangur, Lisa-Maria Needham, Steven F Lee

Proc Natl Acad Sci U S A· June 2020

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The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale.
Klara Kulenkampff, Anna H Lippert, James McColl, Ana Mafalda Santos, Aleks Ponjavic, Steven F Lee

Biophys J· March 2020

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ThX - a next-generation probe for the early detection of amyloid aggregates.
Lisa-Maria Needham, Judith Weber, Juan A Varela, James W B Fyfe, Dung T Do, Steven F Lee

Chem Sci· February 2020

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