Publications by authors named "Steven Grossman"

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Combined inhibition of NAD synthesis and C-terminal binding protein cooperatively induces cell death and inhibits growth of high grade serous ovarian carcinoma.
Kranthi Kumar Chougoni, Jacqueline West, Nicholette St Martin, Diana Dcona, Istem Kose, Steven R Grossman

Sci Rep· December 2025

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Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells.
Esha Madan, António M Palma, Vignesh Vudatha, Amit Kumar, Praveen Bhoopathi, Steven R Grossman

Nat Biotechnol· November 2025

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Oncogenic p53 induces mitotic errors in lung cancer cells by recopying DNA replication forks conferring targetable proliferation advantage.
Swati Palit Deb, Shilpa Singh, Lilia Gheghiani, Rebecca Frum, Steven Grossman

Res Sq· August 2025

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The Causal Effect of Intrapancreatic Fat Deposition on Acute and Chronic Pancreatitis: A Mendelian Randomization Study.
Hajime Yamazaki, Martin Heni, Róbert Wagner, Shunichi Fukuhara, Steven R Grossman

Am J Gastroenterol· December 2024

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Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study.
Hajime Yamazaki, Samantha A Streicher, Lang Wu, Shunichi Fukuhara, Róbert Wagner, Steven R Grossman

Cell Rep Med· December 2024

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Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis.
Tiantian Zhang, Sha Li, Yingcai Adrian Tan, Xiang Chen, Cheryl Zhang, Steven R Grossman

Cancer Lett· November 2024

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Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis.
Kranthi Kumar Chougoni, Victoria Neely, Boxiao Ding, Eziafa Oduah, Vianna T Lam, Steven R Grossman

Cancer Res Commun· October 2024

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Genetic Evidence for a Causal Link between Intra-Pancreatic Fat Deposition and Pancreatitis: a Mendelian Randomization Study.
Hajime Yamazaki, Martin Heni, Róbert Wagner, Shunichi Fukuhara, Steven R Grossman

medRxiv· June 2024

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Proteasome inhibition paradoxically degrades gain-of-function mutant p53 R273H in NSCLC and could have therapeutic implications.
Eziafa I Oduah, Susan T Sharfstein, Nagashree Seetharamu, Steven R Grossman, Larisa Litovchick

Front Oncol· April 2024

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Evidence for a causal link between intra-pancreatic fat deposition and pancreatic cancer: A prospective cohort and Mendelian randomization study.
Hajime Yamazaki, Samantha A Streicher, Lang Wu, Shunichi Fukuhara, Róbert Wagner, Steven R Grossman

Cell Rep Med· February 2024

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Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma.
Kranthi Kumar Chougoni, Haemin Park, Priyadarshan K Damle, Travis Mason, Bo Cheng, Steven R Grossman

Oncogenesis· November 2023

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Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer.
M Michael Dcona, Kranthi Kumar Chougoni, Diana T Dcona, Jacqueline L West, Sahib J Singh, Steven R Grossman

Cancer Res Commun· October 2023

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ADCC's Improving Goal Concordant Care Initiative: Implementing Primary Palliative Care Principles.
Elizabeth T Loggers, Amy A Case, Marcin Chwistek, William Dale, Marvin O Delgado Guay, Steven R Grossman

J Pain Symptom Manage· August 2023

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Genetic Evidence Causally Linking Pancreas Fat to Pancreatic Cancer: A Mendelian Randomization Study.
Hajime Yamazaki, Samantha A Streicher, Lang Wu, Shunichi Fukuhara, Róbert Wagner, Steven R Grossman

medRxiv· April 2023

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Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis.
Tiantian Zhang, Sha Li, Yingcai Adrian Tan, Joseph HyungJoon Na, Zhengming Chen, Steven R Grossman

bioRxiv· April 2023

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Rising Incidence and Racial Disparities of Early-Onset Pancreatic Cancer in the United States, 1995-2018.
Brian Z Huang, Lihua Liu, Juanjuan Zhang, , Stephen J Pandol, Steven R Grossman

Gastroenterology· July 2022

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Flower lose, a cell fitness marker, predicts COVID-19 prognosis.
Michail Yekelchyk, Esha Madan, Jochen Wilhelm, Kirsty R Short, António M Palma, Steven R Grossman

EMBO Mol Med· November 2021

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Cell competition in intratumoral and tumor microenvironment interactions.
Taylor M Parker, Kartik Gupta, António M Palma, Michail Yekelchyk, Paul B Fisher, Steven R Grossman

EMBO J· September 2021

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Clinical Activity and Safety of Cediranib and Olaparib Combination in Patients with Metastatic Pancreatic Ductal Adenocarcinoma without BRCA Mutation.
Joseph W Kim, Dana B Cardin, Ulka N Vaishampayan, Shumei Kato, Steven R Grossman

Oncologist· July 2021

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Cryo-EM structure of CtBP2 confirms tetrameric architecture.
Anne M Jecrois, M Michael Dcona, Xiaoyan Deng, Dipankar Bandyopadhyay, Steven R Grossman

Structure· April 2021

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The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3.
Catherine A Vaughan, Shilpa Singh, Mark A Subler, Jolene J Windle, Kazushi Inoue, Steven R Grossman

Nat Commun· January 2021

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Extraction of high-quality RNA from mouse pancreatic tumors.
Kranthi Kumar Chougoni, Steven R Grossman

MethodsX· November 2020

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Harnessing the vulnerabilities of p53 mutants in lung cancer - Focusing on the proteasome: a new trick for an old foe?
Eziafa I Oduah, Steven R Grossman

Cancer Biol Ther· April 2020

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CtBP determines ovarian cancer cell fate through repression of death receptors.
Boxiao Ding, Fang Yuan, Priyadarshan K Damle, Larisa Litovchick, Ronny Drapkin, Steven R Grossman

Cell Death Dis· April 2020

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p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis.
Boxiao Ding, Alexander Haidurov, Ayesha Chawla, Anita Parmigiani, Gerarda van de Kamp, Steven R Grossman

Oncotarget· December 2019

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