Publications by authors named "Steven J Howe"

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Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle.
Carys S Johnson, Matthew Williams, Kendig Sham, Serena Belluschi, Wenjuan Ma, Steven J Howe

Blood· August 2024

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Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA Construct.
Yu Hua Chen, Celeste Pallant, Christopher J Sampson, Alessia Boiti, Sabine Johnson, Steven J Howe

Mol Ther Methods Clin Dev· December 2020

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The Landscape of Early Clinical Gene Therapies outside of Oncology.
Laure Rittié, Takis Athanasopoulos, Miguel Calero-Garcia, Marie L Davies, David J Dow, Steven J Howe

Mol Ther· October 2019

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Inhibition of Mitochondrial Complex I Impairs Release of α-Galactosidase by Jurkat Cells.
Jonathan R A Lambert, Steven J Howe, Ahad A Rahim, Derek G Burke, Simon J R Heales

Int J Mol Sci· September 2019

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Foamy Virus Vectors Transduce Visceral Organs and Hippocampal Structures following In Vivo Delivery to Neonatal Mice.
John R Counsell, Rajvinder Karda, Juan Antinao Diaz, Louise Carey, Tatiana Wiktorowicz, Steven J Howe

Mol Ther Nucleic Acids· September 2018

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Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors.
Maria E Alonso-Ferrero, Niek P van Til, Kerol Bartolovic, Márcia F Mata, Gerard Wagemaker, Steven J Howe

Exp Hematol· January 2018

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Targeted genome editing restores T cell differentiation in a humanized X-SCID pluripotent stem cell disease model.
Jamal Alzubi, Celeste Pallant, Claudio Mussolino, Steven J Howe, Adrian J Thrasher

Sci Rep· September 2017

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Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.
Conrad A Vink, John R Counsell, Dany P Perocheau, Rajvinder Karda, Suzanne M K Buckley, Steven J Howe

Mol Ther· August 2017

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Erratum: Lentiviral vectors can be used for full-length dystrophin gene therapy.
John R Counsell, Zeinab Asgarian, Jinhong Meng, Veronica Ferrer, Conrad A Vink, Steven J Howe

Sci Rep· August 2017

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Lentiviral vectors can be used for full-length dystrophin gene therapy.
John R Counsell, Zeinab Asgarian, Jinhong Meng, Veronica Ferrer, Conrad A Vink, Steven J Howe

Sci Rep· March 2017

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Lentiviral vectors can be used for full-length dystrophin gene therapy.
John R Counsell, Zeinab Asgarian, Jinhong Meng, Veronica Ferrer, Conrad A Vink, Steven J Howe

Sci Rep· March 2017

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BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity.
Mustafa M Munye, Amelia Shoemark, Robert A Hirst, Juliette M Delhove, Tyson V Sharp, Steven J Howe

Am J Physiol Lung Cell Mol Physiol· February 2017

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Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer.
Mustafa M Munye, Aristides D Tagalakis, Josephine L Barnes, Rachel E Brown, Robin J McAnulty, Steven J Howe

Sci Rep· March 2016

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Evidence for contribution of CD4+ CD25+ regulatory T cells in maintaining immune tolerance to human factor IX following perinatal adenovirus vector delivery.
Megha S Nivsarkar, Suzanne M K Buckley, Alan L Parker, Dany Perocheau, Tristan R McKay, Steven J Howe

J Immunol Res· December 2015

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Systemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates.
Citra N Mattar, Andrew M S Wong, Klemens Hoefer, Maria E Alonso-Ferrero, Suzanne M K Buckley, Steven J Howe

FASEB J· September 2015

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In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters.
Suzanne M K Buckley, Juliette M K M Delhove, Dany P Perocheau, Rajvinder Karda, Ahad A Rahim, Steven J Howe

Sci Rep· July 2015

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Site- and allele-specific polycomb dysregulation in T-cell leukaemia.
Jean-Marc Navarro, Aurore Touzart, Lydie C Pradel, Marie Loosveld, Myriam Koubi, Steven J Howe

Nat Commun· January 2015

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Vector systems for prenatal gene therapy: principles of retrovirus vector design and production.
Steven J Howe, Anil Chandrashekran

Methods Mol Biol· September 2012

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Hematopoietic stem cell and gene therapy corrects primary neuropathology and behavior in mucopolysaccharidosis IIIA mice.
Alexander Langford-Smith, Fiona L Wilkinson, Kia J Langford-Smith, Rebecca J Holley, Ana Sergijenko, Steven J Howe

Mol Ther· August 2012

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Retrovirus and lentivirus vector design and methods of cell conditioning.
Samantha Cooray, Steven J Howe, Adrian J Thrasher

Methods Enzymol· June 2012

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A small molecule modulator of prion protein increases human mesenchymal stem cell lifespan, ex vivo expansion, and engraftment to bone marrow in NOD/SCID mice.
Sindhu T Mohanty, Claire J Cairney, Andrew D Chantry, Sanjeev Madan, James A Fernandes, Steven J Howe

Stem Cells· June 2012

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Perinatal gene transfer to the liver.
Tristan R McKay, Ahad A Rahim, Suzanne M K Buckley, Natalie J Ward, Jerry K Y Chan, Steven J Howe

Curr Pharm Des· February 2012

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Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy.
Annette Deichmann, Martijn H Brugman, Cynthia C Bartholomae, Kerstin Schwarzwaelder, Monique M A Verstegen, Steven J Howe

Mol Ther· November 2011

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Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency.
H Bobby Gaspar, Samantha Cooray, Kimberly C Gilmour, Kathryn L Parsley, Stuart Adams, Steven J Howe

Sci Transl Med· August 2011

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Lentiviral vector integration profiles differ in rodent postmitotic tissues.
Cynthia C Bartholomae, Anne Arens, Kamaljit S Balaggan, Rafael J Yáñez-Muñoz, Eugenio Montini, Steven J Howe

Mol Ther· April 2011

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