Publications by authors named "Steven J Projan"

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Francis Tally and the discovery and development of tigecycline: a personal reminiscence.
Steven J Projan

Clin Infect Dis· January 2010

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Establishment of in vitro susceptibility testing methodologies and comparative activities of piperacillin in combination with the penem {beta}-lactamase inhibitor BLI-489.
Peter J Petersen, C Hal Jones, Aranapakam M Venkatesan, Tarek S Mansour, Steven J Projan

Antimicrob Agents Chemother· February 2009

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Whither antibacterial drug discovery?
Steven J Projan

Drug Discov Today· April 2008

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Late stage antibacterial drugs in the clinical pipeline.
Steven J Projan, Patricia A Bradford

Curr Opin Microbiol· October 2007

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(Genome) size matters.
Steven J Projan

Antimicrob Agents Chemother· April 2007

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Staphylococcal vaccines and immunotherapy: to dream the impossible dream?
Steven J Projan, Mirjana Nesin, Paul M Dunman

Curr Opin Pharmacol· October 2006

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Characterization of the Staphylococcus aureus heat shock, cold shock, stringent, and SOS responses and their effects on log-phase mRNA turnover.
Kelsi L Anderson, Corbette Roberts, Terrence Disz, Veronika Vonstein, Kaitlyn Hwang, Steven J Projan

J Bacteriol· October 2006

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Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390.
James Cassat, Paul M Dunman, Ellen Murphy, Steven J Projan, Karen E Beenken

Microbiology (Reading)· October 2006

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Characterizing the effect of the Staphylococcus aureus virulence factor regulator, SarA, on log-phase mRNA half-lives.
Corbette Roberts, Kelsi L Anderson, Ellen Murphy, Steven J Projan, William Mounts

J Bacteriol· April 2006

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Characterization of the Staphylococcus aureus CidR regulon: elucidation of a novel role for acetoin metabolism in cell death and lysis.
Soo-Jin Yang, Paul M Dunman, Steven J Projan, Kenneth W Bayles

Mol Microbiol· April 2006

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Transcription Profiling of the mgrA Regulon in Staphylococcus aureus.
Thanh T Luong, Paul M Dunman, Ellen Murphy, Steven J Projan, Chia Y Lee

J Bacteriol· March 2006

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Characterization of a strain of community-associated methicillin-resistant Staphylococcus aureus widely disseminated in the United States.
Fred C Tenover, Linda K McDougal, Richard V Goering, George Killgore, Steven J Projan

J Clin Microbiol· January 2006

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Use of ribotyping to retrospectively identify methicillin-resistant Staphylococcus aureus isolates from phase 3 clinical trials for tigecycline that are genotypically related to community-associated isolates.
Fionnuala McAleese, Ellen Murphy, Timothy Babinchak, Guy Singh, Battouli Said-Salim, Steven J Projan

Antimicrob Agents Chemother· November 2005

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Differential proteomic analysis of bronchoalveolar lavage fluid in asthmatics following segmental antigen challenge.
Jiang Wu, Michiko Kobayashi, Eric A Sousa, Wei Liu, Jie Cai, Steven J Projan

Mol Cell Proteomics· September 2005

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A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline.
Fionnuala McAleese, Peter Petersen, Alexey Ruzin, Paul M Dunman, Ellen Murphy, Steven J Projan

Antimicrob Agents Chemother· May 2005

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Comparative genomics of Staphylococcus aureus musculoskeletal isolates.
James E Cassat, Paul M Dunman, Fionnuala McAleese, Ellen Murphy, Steven J Projan

J Bacteriol· January 2005

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Effect of mild acid on gene expression in Staphylococcus aureus.
Brian Weinrick, Paul M Dunman, Fionnuala McAleese, Ellen Murphy, Steven J Projan

J Bacteriol· December 2004

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Small molecules for small minds? The case for biologic pharmaceuticals.
Steven J Projan, Davinder Gill, Zhijian Lu, Steven H Herrmann

Expert Opin Biol Ther· August 2004

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Hydrophobic acetal and ketal derivatives of mannopeptimycin-alpha and desmethylhexahydromannopeptimycin-alpha: semisynthetic glycopeptides with potent activity against Gram-positive bacteria.
Russell G Dushin, Ting-Zhong Wang, Phaik-Eng Sum, Haiyin He, Alan G Sutherland, Steven J Projan

J Med Chem· July 2004

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Global gene expression in Staphylococcus aureus biofilms.
Karen E Beenken, Paul M Dunman, Fionnuala McAleese, Daphne Macapagal, Ellen Murphy, Steven J Projan

J Bacteriol· July 2004

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Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA.
Gesine Bauer, Christian Berens, Steven J Projan, Wolfgang Hillen

J Antimicrob Chemother· April 2004

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Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infection.
William J Weiss, Eileen Lenoy, Timothy Murphy, LuAnna Tardio, Pamela Burgio, Steven J Projan

J Antimicrob Chemother· March 2004

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Recurrent episodes of shock-like syndrome caused by the same strain of vancomycin-resistant Enterococcus faecium in a pediatric patient.
Laszlo Papp, David F McNeeley, Steven J Projan, Patricia A Bradford, Adam Frost

Microb Drug Resist· October 2003

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Why is big Pharma getting out of antibacterial drug discovery?
Steven J Projan

Curr Opin Microbiol· October 2003

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Inactivation of mprF affects vancomycin susceptibility in Staphylococcus aureus.
Alexey Ruzin, Anatoly Severin, Soraya L Moghazeh, Jerome Etienne, Patricia A Bradford, Steven J Projan

Biochim Biophys Acta· May 2003

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