Publications by authors named "Steven K Laughlin"

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Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3).
Michael P Clark, Kelly M George, Roger G Bookland, Jack Chen, Steven K Laughlin

Bioorg Med Chem Lett· March 2007

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Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3.
Jack J Chen, Kumar D Thakur, Michael P Clark, Steven K Laughlin, Kelly M George

Bioorg Med Chem Lett· November 2006

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The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production.
Mark Sabat, John C Vanrens, Michael P Clark, Todd A Brugel, Jennifer Maier, Steven K Laughlin

Bioorg Med Chem Lett· August 2006

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Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2.
Jennifer A Maier, Todd A Brugel, Michael P Clark, Mark Sabat, Adam Golebiowski, Steven K Laughlin

Bioorg Med Chem Lett· July 2006

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Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1.
Todd A Brugel, Jennifer A Maier, Michael P Clark, Mark Sabat, Adam Golebiowski, Steven K Laughlin

Bioorg Med Chem Lett· July 2006

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The development of monocyclic pyrazolone based cytokine synthesis inhibitors.
Adam Golebiowski, Jennifer A Townes, Matthew J Laufersweiler, Todd A Brugel, Michael P Clark, Steven K Laughlin

Bioorg Med Chem Lett· May 2005

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The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production.
Steven K Laughlin, Michael P Clark, Jane F Djung, Adam Golebiowski, Todd A Brugel

Bioorg Med Chem Lett· May 2005

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The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones.
Matthew J Laufersweiler, Todd A Brugel, Michael P Clark, Adam Golebiowski, Roger G Bookland, Steven K Laughlin

Bioorg Med Chem Lett· August 2004

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Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production.
Michael P Clark, Steven K Laughlin, Matthew J Laufersweiler, Roger G Bookland, Todd A Brugel

J Med Chem· May 2004

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