Publications by authors named "Steven L Kelly"

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Acquired amphotericin B resistance attributed to a mutated in .
Lauryn Massic, Laura A Doorley, Sarah J Jones, Irene Richardson, Danielle Denise Siao, Steven L Kelly

Antimicrob Agents Chemother· November 2025

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New Generation Modified Azole Antifungals against Multidrug-Resistant .
Yiyuan Chen, Yunxiao Li, Kazi S Nahar, Md Mahbub Hasan, Caleb Marsh, Steven L Kelly

J Med Chem· July 2025

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Design and Synthesis of Ketoconazole Derivatives as Innovative Anti-Infective Agents.
Gioele Renzi, Andrea Angeli, Silvia Selleri, Costanza Spadini, Nicolo' Mezzasalma, Steven L Kelly

Arch Pharm (Weinheim)· July 2025

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Unique Structural Features Relate to Evolutionary Adaptation of Cytochrome P450 in the Abyssal Zone.
Tatiana Y Hargrove, David C Lamb, Zdzislaw Wawrzak, George Minasov, Jared V Goldstone, Steven L Kelly

Int J Mol Sci· June 2025

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Exploring medium and long arm extensions of 1,2,4-triazole derivatives as 14α-demethylase (CYP51) inhibitors.
Marwa Alsulaimany, Faizah A Binjubair, Esra Tatar, Diane E Kelly, Steven L Kelly

RSC Med Chem· May 2025

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Acquired Amphotericin B Resistance Attributed to a Mutated in .
Lauryn Massic, Laura A Doorley, Sarah J Jones, Irene Richardson, Danielle Denise Siao, Steven L Kelly

bioRxiv· April 2025

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Artificial ER-Mitochondrion Tethering Restores Erg6 Localization and Lipid Droplet Formation in and Cells.
Haiqiong Chen, Rinse de Boer, David C Lamb, Steven L Kelly, Ida J van der Klei

Contact (Thousand Oaks)· April 2025

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Crystal structure of cytochrome P450 NysL and the structural basis for stereo- and regio-selective oxidation of antifungal macrolides.
Vidhi C Murarka, Jenny S Kim, David C Lamb, Steven L Kelly, Thomas L Poulos

J Biol Chem· March 2025

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Genetic interaction analysis of transcription factors and in the regulation of respiration and fluconazole susceptibility.
Tomye L Ollinger, Robert Zarnowski, Josie E Parker, Steven L Kelly, David R Andes

Antimicrob Agents Chemother· February 2025

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Cytochrome b5 occurrence in giant and other viruses belonging to the phylum Nucleocytoviricota.
David C Lamb, Jared V Goldstone, Djamal Brahim Belhaouari, Julien Andréani, Ayesha Farooqi, Steven L Kelly

Npj Viruses· February 2025

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Unique structural features in a deep-sea CYP51 relate to high pressure adaptation.
Tatiana Y Hargrove, David C Lamb, Zdzislaw Wawrzak, George Minasov, Jared V Goldstone, Steven L Kelly

Res Sq· December 2024

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Vertebrate endocrine disruptors induce sex-reversal in blue mussels.
K Garrett Evensen, Emily Rusin, William E Robinson, Claire L Price, Steven L Kelly

Sci Rep· October 2024

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Cytochromes b5 Occurrence in Viruses Belonging to the Order Megavirales.
David C Lamb, Jared V Goldstone, Djamal Brahim Belhaouari, Julien Andréani, Ayesha Farooqi, Steven L Kelly

Res Sq· October 2024

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Deletion of the Candida albicans TLO gene family results in alterations in membrane sterol composition and fluconazole tolerance.
James O'Connor-Moneley, Jessica Fletcher, Cody Bean, Josie Parker, Steven L Kelly

PLoS One· August 2024

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Identification of Potent and Selective Inhibitors of : Structural Insights into Sterol 14α-Demethylase as a Key Drug Target.
Tatiana Y Hargrove, David C Lamb, Zdzislaw Wawrzak, Marcus Hull, Steven L Kelly

J Med Chem· May 2024

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The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species.
Jinhong Xie, Jeffrey M Rybak, Adela Martin-Vicente, Xabier Guruceaga, Harrison I Thorn, Steven L Kelly

Nat Commun· May 2024

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Biosynthesis of a new skyllamycin in : a cytochrome P450 forms an epoxide in the cinnamoyl chain.
Yuhao Song, Jose A Amaya, Vidhi C Murarka, Hugo Mendez, Mark Hogan, Steven L Kelly

Org Biomol Chem· April 2024

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A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1.
Jeffrey M Rybak, Jinhong Xie, Adela Martin-Vicente, Xabier Guruceaga, Harrison I Thorn, Steven L Kelly

Nat Commun· April 2024

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Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s.
Jared V Goldstone, David C Lamb, Steven L Kelly, Galina I Lepesheva, John J Stegeman

J Inorg Biochem· August 2023

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Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in as a Major Mechanism Conferring Reduced Susceptibility to Amphotericin B in Candida kefyr.
Mohammad Asadzadeh, Wadha Alfouzan, Josie E Parker, Jacques F Meis, Steven L Kelly

Microbiol Spectr· August 2023

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The sterol C-24 methyltransferase encoding gene, , is essential for viability of species.
Jinhong Xie, Jeffrey M Rybak, Adela Martin-Vicente, Xabier Guruceaga, Harrison I Thorn, Steven L Kelly

bioRxiv· August 2023

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Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics.
Tatiana Y Hargrove, David C Lamb, Jarrod A Smith, Zdzislaw Wawrzak, Steven L Kelly

Sci Rep· September 2022

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Glow flow ionization mass spectrometry of small molecules. A comparison of a glow flow ionization source ('GlowFlow') with electrospray ionization and atmospheric pressure chemical ionization.
Rhodri N Owen, Stevan Bajic, Steven L Kelly, Michael R Morris, A Gareth Brenton

Rapid Commun Mass Spectrom· August 2022

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Characterization of a Virally Encoded Flavodoxin That Can Drive Bacterial Cytochrome P450 Monooxygenase Activity.
David C Lamb, Jared V Goldstone, Bin Zhao, Li Lei, Jonathan G L Mullins, Steven L Kelly

Biomolecules· August 2022

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Metabolic arsenal of giant viruses: Host hijack or self-use?
Djamal Brahim Belhaouari, Gabriel Augusto Pires De Souza, David C Lamb, Steven L Kelly, Jared V Goldstone

Elife· July 2022

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