Publications by authors named "Steven Opal"

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Validation of SeptiCyte RAPID to Discriminate Sepsis from Non-Infectious Systemic Inflammation.
Robert Balk, Annette M Esper, Greg S Martin, Russell R Miller, Bert K Lopansri, Steven Opal

J Clin Med· February 2024

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Antimicrobial Efficacy of Continuous Low-Irradiance Phototherapy Against Multidrug-Resistant Organisms.
Patrick McMullan, Alexander B White, Oluwadara Coker, Steven Opal, Shayan A McGee

Photobiomodul Photomed Laser Surg· September 2022

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A pilot study of an anti-endotoxin Ig-enriched bovine colostrum to prevent experimental sepsis.
Alan S Cross, Steven M Opal, John E Palardy, Surekha Shridhar, Scott M Baliban

Innate Immun· April 2021

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Therapeutic Rationale for Endotoxin Removal with Polymyxin B Immobilized Fiber Column (PMX) for Septic Shock.
Hisataka Shoji, Steven M Opal

Int J Mol Sci· February 2021

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Steroids for sepsis and ARDS: this eternal controversy remains with COVID-19.
Jean Carlet, Didier Payen, Steven M Opal

Lancet· October 2020

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Safety and Pharmacokinetics of Recombinant Human Plasma Gelsolin in Patients Hospitalized for Nonsevere Community-Acquired Pneumonia.
Abla Tannous, Susan L Levinson, James Bolognese, Steven M Opal, Mark J DiNubile

Antimicrob Agents Chemother· September 2020

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Reply to Siniorakis et al., "COVID-19 Interference with Renin-Angiotensin System in the Context of Heart Failure".
David S Fedson, Steven M Opal, Ole Martin Rordam

mBio· May 2020

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Hiding in Plain Sight: an Approach to Treating Patients with Severe COVID-19 Infection.
David S Fedson, Steven M Opal, Ole Martin Rordam

mBio· March 2020

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Activating Immunity to Fight a Foe - A New Path.
Richard S Hotchkiss, Steven M Opal

N Engl J Med· March 2020

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Biomarkers of Infection and Sepsis.
Steven M Opal, Xavier Wittebole

Crit Care Clin· January 2020

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Coinfection With Influenza A Virus and : An Underrecognized Impact on Host Resistance and Tolerance to Pulmonary Infections.
Kayla M Lee, Jenna Morris-Love, Damien J Cabral, Peter Belenky, Steven M Opal

Front Immunol· October 2019

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Effect of Selepressin vs Placebo on Ventilator- and Vasopressor-Free Days in Patients With Septic Shock: The SEPSIS-ACT Randomized Clinical Trial.
Pierre-Francois Laterre, Scott M Berry, Allan Blemings, Jan E Carlsen, Bruno François, Steven M Opal

JAMA· October 2019

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Should we continue to test soluble thrombomodulin, or other systemic anticoagulants, as a life-saving therapy for sepsis-induced coagulopathy?
Pierre-Francois Laterre, Mitchell M Levy, Xavier Wittebole, Thierry Dugernier, Bruno Francois, Steven M Opal

Anaesth Crit Care Pain Med· October 2019

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An Integrated Safety Summary of Omadacycline, a Novel Aminomethylcycline Antibiotic.
Steven Opal, Thomas M File, Tom van der Poll, Evan Tzanis, Surya Chitra

Clin Infect Dis· August 2019

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Inter-α-inhibitor Ameliorates Endothelial Inflammation in Sepsis.
Vandy P Stober, Yow-Pin Lim, Steven Opal, Lisheng Zhuo, Koji Kimata

Lung· June 2019

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Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial.
Jean-Louis Vincent, Bruno Francois, Igor Zabolotskikh, Mradul Kumar Daga, Jean-Baptiste Lascarrou, Steven M Opal

JAMA· May 2019

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Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis.
Christopher W Seymour, Jason N Kennedy, Shu Wang, Chung-Chou H Chang, Corrine F Elliott, Steven M Opal

JAMA· May 2019

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Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis.
Pragnya Das, Santosh K Panda, Beamon Agarwal, Sumita Behera, Syed M Ali, Steven M Opal

Sci Rep· February 2019

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Physician agreement on the diagnosis of sepsis in the intensive care unit: estimation of concordance and analysis of underlying factors in a multicenter cohort.
Bert K Lopansri, Russell R Miller Iii, John P Burke, Mitchell Levy, Steven Opal

J Intensive Care· February 2019

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Whatever happened to the Shwartzman phenomenon?
Abdullah B Chahin, Jason M Opal, Steven M Opal

Innate Immun· November 2018

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Validation of a Host Response Assay, SeptiCyte LAB, for Discriminating Sepsis from Systemic Inflammatory Response Syndrome in the ICU.
Russell R Miller, Bert K Lopansri, John P Burke, Mitchell Levy, Steven Opal

Am J Respir Crit Care Med· October 2018

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Antibiotic Stewardship: Strategies to Minimize Antibiotic Resistance While Maximizing Antibiotic Effectiveness.
Cheston B Cunha, Steven M Opal

Med Clin North Am· September 2018

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Soluble programmed cell death protein-1 and programmed cell death ligand-1 in sepsis.
Debasree Banerjee, Sean Monaghan, Runping Zhao, Thomas Walsh, Amy Palmisciano, Steven Opal

Crit Care· June 2018

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Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study).
Tobias Welte, R Phillip Dellinger, Henning Ebelt, Miguel Ferrer, Steven M Opal

Intensive Care Med· April 2018

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Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial.
Roger J Lewis, Derek C Angus, Pierre-François Laterre, Anne Louise Kjølbye, Egbert van der Meulen, Steven M Opal

Ann Am Thorac Soc· February 2018

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