Publications by authors named "Steven T Olson"

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On 'The polymerization of proteins: the action of thrombin on fibrinogen' by Koloman Laki.
Steven T Olson

Arch Biochem Biophys· September 2022

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Heparin activation of protein Z-dependent protease inhibitor (ZPI) allosterically blocks protein Z activation through an extended heparin-binding site.
Xin Huang, Richard Swanson, Steven T Olson

J Biol Chem· June 2022

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Paramount Importance of Core Conformational Changes for Heparin Allosteric Activation of Antithrombin.
Gonzalo Izaguirre, Richard Swanson, Ryan Roth, Peter G W Gettins, Steven T Olson

Biochemistry· April 2021

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An in vitro Model System for Evaluating Remote Magnetic Nanoparticle Movement and Fibrinolysis.
Sebastian P Pernal, Alexander J Willis, Michael E Sabo, Laura M Moore, Steven T Olson

Int J Nanomedicine· July 2020

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Cooperative Interactions of Three Hotspot Heparin Binding Residues Are Critical for Allosteric Activation of Antithrombin by Heparin.
Benjamin Richard, Richard Swanson, Gonzalo Izaguirre, Steven T Olson

Biochemistry· April 2018

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Disease-causing mutations in the serpin antithrombin reveal a key domain critical for inhibiting protease activities.
Sonia Águila, Gonzalo Izaguirre, Irene Martínez-Martínez, Vicente Vicente, Steven T Olson

J Biol Chem· October 2017

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Lipid oxidation inactivates the anticoagulant function of protein Z-dependent protease inhibitor (ZPI).
Xin Huang, Baoxin Liu, Yidong Wei, Ryan Beyea, Han Yan, Steven T Olson

J Biol Chem· September 2017

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Inhibitory serpins. New insights into their folding, polymerization, regulation and clearance.
Peter G W Gettins, Steven T Olson

Biochem J· August 2016

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The protease cathepsin L regulates Th17 cell differentiation.
Lifei Hou, Jessica Cooley, Richard Swanson, Poh Chee Ong, Robert N Pike, Steven T Olson

J Autoimmun· December 2015

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Saturation Mutagenesis of the Antithrombin Reactive Center Loop P14 Residue Supports a Three-step Mechanism of Heparin Allosteric Activation Involving Intermediate and Fully Activated States.
Ryan Roth, Richard Swanson, Gonzalo Izaguirre, Susan C Bock, Peter G W Gettins, Steven T Olson

J Biol Chem· November 2015

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Thermodynamic and kinetic characterization of the protein Z-dependent protease inhibitor (ZPI)-protein Z interaction reveals an unexpected role for ZPI Lys-239.
Xin Huang, Jian Zhou, Aiwu Zhou, Steven T Olson

J Biol Chem· April 2015

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Conformational activation of antithrombin by heparin involves an altered exosite interaction with protease.
Gonzalo Izaguirre, Sonia Aguila, Lixin Qi, Richard Swanson, Ryan Roth, Steven T Olson

J Biol Chem· December 2014

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Targeted mutagenesis of zebrafish antithrombin III triggers disseminated intravascular coagulation and thrombosis, revealing insight into function.
Yang Liu, Colin A Kretz, Morgan L Maeder, Catherine E Richter, Philip Tsao, Steven T Olson

Blood· July 2014

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Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules.
Julian Nomme, Jennifer M Murphy, Ying Su, Natasha D Sansone, Amanda L Armijo, Steven T Olson

Acta Crystallogr D Biol Crystallogr· January 2014

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Kinetic intermediates en route to the final serpin-protease complex: studies of complexes of α1-protease inhibitor with trypsin.
Ashoka A Maddur, Richard Swanson, Gonzalo Izaguirre, Peter G W Gettins, Steven T Olson

J Biol Chem· November 2013

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The allosteric mechanism of activation of antithrombin as an inhibitor of factor IXa and factor Xa: heparin-independent full activation through mutations adjacent to helix D.
Alexey Dementiev, Richard Swanson, Ryan Roth, Giulia Isetti, Gonzalo Izaguirre, Steven T Olson

J Biol Chem· November 2013

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Identification of serpin determinants of specificity and selectivity for furin inhibition through studies of α1PDX (α1-protease inhibitor Portland)-serpin B8 and furin active-site loop chimeras.
Gonzalo Izaguirre, Lixin Qi, Mary Lima, Steven T Olson

J Biol Chem· July 2013

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Cathepsin B controls the persistence of memory CD8+ T lymphocytes.
Susan M Byrne, Anne Aucher, Syarifah Alyahya, Matthew Elder, Steven T Olson

J Immunol· August 2012

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Structural basis for catalytic activation of protein Z-dependent protease inhibitor (ZPI) by protein Z.
Xin Huang, Yahui Yan, Yizheng Tu, Jeffrey Gatti, George J Broze, Steven T Olson

Blood· August 2012

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Characterization of the heparin-binding site of the protein z-dependent protease inhibitor.
Likui Yang, Qiulan Ding, Xin Huang, Steven T Olson, Alireza R Rezaie

Biochemistry· May 2012

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Specificity and selectivity profile of EP217609: a new neutralizable dual-action anticoagulant that targets thrombin and factor Xa.
Steven T Olson, Richard Swanson, Maurice Petitou

Blood· March 2012

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Matriptase is inhibited by extravascular antithrombin in epithelial cells but not in most carcinoma cells.
Feng-Pai Chou, Han Xu, Ming-Shyue Lee, Ya-Wen Chen, O X Durand Richards, Steven T Olson

Am J Physiol Cell Physiol· November 2011

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Regulation of proteases by protein inhibitors of the serpin superfamily.
Steven T Olson, Peter G W Gettins

Prog Mol Biol Transl Sci· July 2011

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Heparin is a major activator of the anticoagulant serpin, protein Z-dependent protease inhibitor.
Xin Huang, Alireza R Rezaie, George J Broze, Steven T Olson

J Biol Chem· March 2011

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Kinetic evidence that allosteric activation of antithrombin by heparin is mediated by two sequential conformational changes.
Sophia Schedin-Weiss, Benjamin Richard, Steven T Olson

Arch Biochem Biophys· December 2010

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